DE69935539D1 - Untersuchungsverfahren für Protein-Protein-Interaktion - Google Patents

Untersuchungsverfahren für Protein-Protein-Interaktion

Info

Publication number
DE69935539D1
DE69935539D1 DE69935539T DE69935539T DE69935539D1 DE 69935539 D1 DE69935539 D1 DE 69935539D1 DE 69935539 T DE69935539 T DE 69935539T DE 69935539 T DE69935539 T DE 69935539T DE 69935539 D1 DE69935539 D1 DE 69935539D1
Authority
DE
Germany
Prior art keywords
protein
interaction
investigation procedure
investigation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69935539T
Other languages
English (en)
Other versions
DE69935539T2 (de
Inventor
Michael Phillip Weiner
Richard Gordon Buckholz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/049,325 external-priority patent/US6332897B1/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE69935539D1 publication Critical patent/DE69935539D1/de
Publication of DE69935539T2 publication Critical patent/DE69935539T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00306—Reactor vessels in a multiple arrangement
    • B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315—Microtiter plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69935539T 1998-03-26 1999-03-26 Untersuchungsverfahren für Protein-Protein-Interaktion Expired - Lifetime DE69935539T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7948098P 1998-03-26 1998-03-26
US79480P 1998-03-26
US09/049,325 US6332897B1 (en) 1998-03-27 1998-03-27 Assay methods
US49325 1998-03-27
PCT/US1999/006671 WO1999049294A2 (en) 1998-03-26 1999-03-26 Assay methods

Publications (2)

Publication Number Publication Date
DE69935539D1 true DE69935539D1 (de) 2007-04-26
DE69935539T2 DE69935539T2 (de) 2007-12-06

Family

ID=26727069

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69935539T Expired - Lifetime DE69935539T2 (de) 1998-03-26 1999-03-26 Untersuchungsverfahren für Protein-Protein-Interaktion

Country Status (10)

Country Link
EP (1) EP1315958B1 (de)
JP (1) JP4440464B2 (de)
AT (1) ATE356865T1 (de)
AU (1) AU775227B2 (de)
CA (1) CA2325447C (de)
DE (1) DE69935539T2 (de)
ES (1) ES2284245T3 (de)
IL (2) IL138353A0 (de)
IS (1) IS2530B (de)
WO (1) WO1999049294A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794127B1 (en) 1997-06-16 2004-09-21 Diversa Corporation Capillary array-based sample screening
US6972183B1 (en) 1997-06-16 2005-12-06 Diversa Corporation Capillary array-based enzyme screening
IL144251A0 (en) * 1999-11-22 2002-05-23 Diversa Corp Capillary array-based sample screening
WO2002055657A2 (en) * 2000-12-21 2002-07-18 Myriad Genetics Inc Protein-protein interactions
ATE489480T1 (de) * 2003-10-09 2010-12-15 Ecole Polytech Verfahren zur identifizierung geeigneter fragmentierungsstellen in einem reporterprotein
JP4554269B2 (ja) * 2004-05-13 2010-09-29 財団法人かずさディー・エヌ・エー研究所 液体培養による大腸菌ツーハイブリッドシステム
WO2010026601A2 (en) * 2008-09-02 2010-03-11 Lupin Limited Vector for identification, selection and expression of recombinants
WO2017205852A2 (en) 2016-05-27 2017-11-30 Synthex, Inc. Protein interfaces
GB2584210B (en) 2017-11-22 2022-03-16 Synthex Inc Peptides for inhibiting RAD51

Also Published As

Publication number Publication date
EP1315958A4 (de) 2005-01-05
AU3365899A (en) 1999-10-18
JP4440464B2 (ja) 2010-03-24
EP1315958A2 (de) 2003-06-04
EP1315958B1 (de) 2007-03-14
IS5620A (is) 2000-09-08
IS2530B (is) 2009-07-15
JP2003524371A (ja) 2003-08-19
ES2284245T3 (es) 2007-11-01
CA2325447A1 (en) 1999-09-30
IL138353A (en) 2007-05-15
DE69935539T2 (de) 2007-12-06
CA2325447C (en) 2007-08-21
WO1999049294A3 (en) 2003-03-20
WO1999049294A2 (en) 1999-09-30
AU775227B2 (en) 2004-07-22
ATE356865T1 (de) 2007-04-15
IL138353A0 (en) 2001-10-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition