DE69925757D1 - Dextran-maleinsäuremonoester und hydrogele daraus - Google Patents

Dextran-maleinsäuremonoester und hydrogele daraus

Info

Publication number
DE69925757D1
DE69925757D1 DE69925757T DE69925757T DE69925757D1 DE 69925757 D1 DE69925757 D1 DE 69925757D1 DE 69925757 T DE69925757 T DE 69925757T DE 69925757 T DE69925757 T DE 69925757T DE 69925757 D1 DE69925757 D1 DE 69925757D1
Authority
DE
Germany
Prior art keywords
hydrogels
dextran
maleic acid
hydrogeles
acid monoester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69925757T
Other languages
English (en)
Other versions
DE69925757T2 (de
Inventor
Sin-Hee Kim
Chee-Youb Won
Chih-Chang Chu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cornell Research Foundation Inc
Original Assignee
Cornell Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Research Foundation Inc filed Critical Cornell Research Foundation Inc
Application granted granted Critical
Publication of DE69925757D1 publication Critical patent/DE69925757D1/de
Publication of DE69925757T2 publication Critical patent/DE69925757T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69925757T 1998-08-31 1999-08-25 Dextran-maleinsäuremonoester und hydrogele daraus Expired - Lifetime DE69925757T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9857198P 1998-08-31 1998-08-31
US98571P 1998-08-31
PCT/US1999/018818 WO2000012619A1 (en) 1998-08-31 1999-08-25 Dextran-maleic acid monoesters and hydrogels based thereon

Publications (2)

Publication Number Publication Date
DE69925757D1 true DE69925757D1 (de) 2005-07-14
DE69925757T2 DE69925757T2 (de) 2006-03-23

Family

ID=22269907

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925757T Expired - Lifetime DE69925757T2 (de) 1998-08-31 1999-08-25 Dextran-maleinsäuremonoester und hydrogele daraus

Country Status (8)

Country Link
US (1) US6476204B1 (de)
EP (1) EP1147148B1 (de)
AT (1) ATE297440T1 (de)
AU (1) AU5571399A (de)
CA (1) CA2339166C (de)
DE (1) DE69925757T2 (de)
ES (1) ES2241314T3 (de)
WO (1) WO2000012619A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000060956A1 (en) 1999-04-12 2000-10-19 Cornell Research Foundation, Inc. Hydrogel-forming system with hydrophobic and hydrophilic components
US6716445B2 (en) 1999-04-12 2004-04-06 Cornell Research Foundation, Inc. Hydrogel entrapping therapeutic agent and stent with coating comprising this
US20060177416A1 (en) 2003-10-14 2006-08-10 Medivas, Llc Polymer particle delivery compositions and methods of use
US20040018228A1 (en) * 2000-11-06 2004-01-29 Afmedica, Inc. Compositions and methods for reducing scar tissue formation
AU2002316340B2 (en) 2001-08-02 2006-09-07 Cornell Research Foundation, Inc. Biodegradable polyhydric alcohol esters
CN100341484C (zh) * 2003-01-16 2007-10-10 康乃尔研究基金会有限公司 部分可生物降解的温度和pH敏感的水凝胶
EP1926780B1 (de) 2005-09-22 2013-08-14 Medivas, LLC Bis-( -amino)-diol-diester-haltige poly(esteramid) und poly(esterurethan)-zusammensetzungen und verwendungsverfahren
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
JP2009530484A (ja) * 2006-03-24 2009-08-27 メディバス エルエルシー アルキレン−ジカルボキシラート含有の生分解性ポリ（エステル−アミド）および使用法
JP2012506478A (ja) * 2008-10-22 2012-03-15 サーモディクス，インコーポレイティド 膨潤性および生分解性を有するポリマーマトリクス並びにその製造方法
AU2009333168C1 (en) * 2008-12-17 2017-04-20 The Johns Hopkins University Biocompatible polysaccharide-based hydrogels
US8900868B2 (en) 2009-11-10 2014-12-02 The Johns Hopkins University Hydrogel-based vascular lineage cell growth media and uses thereof
EP2575498A1 (de) 2010-05-04 2013-04-10 Cargill, Incorporated Fettersatzstoffe und füllmaterialien
CA2803983C (en) 2010-06-30 2019-12-03 Sharon Gerecht Functional vascularization with biocompatible polysaccharide-based hydrogels
EP3159368A1 (de) 2011-06-23 2017-04-26 DSM IP Assets B.V. Neue biologisch abbaubare polyesteramid-copolymere zur arzneimittelabgabe
US9873765B2 (en) 2011-06-23 2018-01-23 Dsm Ip Assets, B.V. Biodegradable polyesteramide copolymers for drug delivery
EP2836233A1 (de) 2012-04-13 2015-02-18 Nanoscape AG Formulierung mit verzögerter freisetzung
US10538864B2 (en) 2012-10-24 2020-01-21 Dsm Ip Assets, B.V. Fibers comprising polyesteramide copolymers for drug delivery
CN107106509B (zh) 2014-12-18 2021-11-30 帝斯曼知识产权资产管理有限公司 用于递送酸敏感药物的药物递送系统
JP7313149B2 (ja) * 2016-01-17 2023-07-24 スン，グオミン 生体適合性多糖ヒドロゲル及び使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002173A (en) * 1974-07-23 1977-01-11 International Paper Company Diester crosslinked polyglucan hydrogels and reticulated sponges thereof
US4032488A (en) * 1975-10-03 1977-06-28 Meito Sangyo Kabushiki Kaisha Dextran ester-olefin compound copolymer and process for preparing same
GB8602115D0 (en) * 1986-01-29 1986-03-05 Courtaulds Plc Absorbent fibres
US4920158A (en) 1989-10-11 1990-04-24 Medipro Sciences Limited Hydrogel-forming wound dressing or skin coating material
US5013769A (en) * 1988-08-22 1991-05-07 Medipro Sciences Limited Method of making a hydrogel-forming wound dressing or skin coating material
US5527856A (en) 1988-11-21 1996-06-18 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
CA2121129A1 (en) * 1991-10-29 1993-05-13 Patrick Soon-Shiong Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
US5393798A (en) 1992-06-05 1995-02-28 Spenco Medical Corporation Hydrogel material and method of preparation
US5541304A (en) 1994-05-02 1996-07-30 Hercules Incorporated Crosslinked hydrogel compositions with improved mechanical performance
US5658592A (en) 1994-05-13 1997-08-19 Kuraray Co., Ltd. Medical crosslinked polymer gel of carboxylic polysaccharide and diaminoalkane
DE4426008A1 (de) 1994-07-22 1996-01-25 Cassella Ag Hydrophile, hochquellfähige Hydrogele
DE19529409A1 (de) 1995-08-10 1997-02-13 Wolff Walsrode Ag Maleinsäureadditionsproduktgruppen enthaltende, thermoplastische und biologisch abbaubare Polysaccharidester/-etherester

Also Published As

Publication number Publication date
EP1147148A1 (de) 2001-10-24
DE69925757T2 (de) 2006-03-23
CA2339166C (en) 2008-01-15
ATE297440T1 (de) 2005-06-15
CA2339166A1 (en) 2000-03-09
EP1147148A4 (de) 2004-04-07
WO2000012619A1 (en) 2000-03-09
ES2241314T3 (es) 2005-10-16
US6476204B1 (en) 2002-11-05
AU5571399A (en) 2000-03-21
EP1147148B1 (de) 2005-06-08

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