DE69921309D1 - Erhöhung der elektrischen leitfähigkeit und der kontraktionskraft des herzens mittels zweiphasiger reizung des intravasalraumes des herzens - Google Patents
Erhöhung der elektrischen leitfähigkeit und der kontraktionskraft des herzens mittels zweiphasiger reizung des intravasalraumes des herzensInfo
- Publication number
- DE69921309D1 DE69921309D1 DE69921309T DE69921309T DE69921309D1 DE 69921309 D1 DE69921309 D1 DE 69921309D1 DE 69921309 T DE69921309 T DE 69921309T DE 69921309 T DE69921309 T DE 69921309T DE 69921309 D1 DE69921309 D1 DE 69921309D1
- Authority
- DE
- Germany
- Prior art keywords
- heart
- irritation
- increasing
- phase
- electrical conductivity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/3621—Heart stimulators for treating or preventing abnormally high heart rate
- A61N1/3622—Heart stimulators for treating or preventing abnormally high heart rate comprising two or more electrodes co-operating with different heart regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/368—Heart stimulators controlled by a physiological parameter, e.g. heart potential comprising more than one electrode co-operating with different heart regions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/37—Monitoring; Protecting
- A61N1/371—Capture, i.e. successful stimulation
- A61N1/3712—Auto-capture, i.e. automatic adjustment of the stimulation threshold
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/362—Heart stimulators
- A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
- A61N1/36514—Heart stimulators controlled by a physiological parameter, e.g. heart potential controlled by a physiological quantity other than heart potential, e.g. blood pressure
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/008,636 US6136019A (en) | 1996-08-19 | 1998-01-16 | Augmentation of electrical conduction and contractility by biphasic cardiac pacing administered via the cardiac blood pool |
US8636 | 1998-01-16 | ||
PCT/US1999/000879 WO1999036124A1 (en) | 1998-01-16 | 1999-01-13 | Augmentation of electrical conduction and contractibility by biphasic cardiac pacing administered via the cardiac blood pool |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69921309D1 true DE69921309D1 (de) | 2004-11-25 |
DE69921309T2 DE69921309T2 (de) | 2005-10-13 |
Family
ID=21732757
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69921309T Expired - Fee Related DE69921309T2 (de) | 1998-01-16 | 1999-01-13 | Erhöhung der elektrischen leitfähigkeit und der kontraktionskraft des herzens mittels zweiphasiger reizung des intravasalraumes des herzens |
Country Status (19)
Country | Link |
---|---|
US (1) | US6136019A (de) |
EP (1) | EP1064048B1 (de) |
AP (1) | AP2002002486A0 (de) |
AT (1) | ATE279958T1 (de) |
AU (1) | AU2321199A (de) |
CA (1) | CA2318101C (de) |
CZ (1) | CZ299883B6 (de) |
DE (1) | DE69921309T2 (de) |
DK (1) | DK1064048T3 (de) |
EA (1) | EA003163B1 (de) |
ES (1) | ES2229670T3 (de) |
GE (1) | GEP20022789B (de) |
HU (1) | HUP0102503A2 (de) |
ID (1) | ID26205A (de) |
IL (1) | IL137321A (de) |
NO (1) | NO20003732L (de) |
NZ (1) | NZ505749A (de) |
SK (1) | SK286698B6 (de) |
WO (1) | WO1999036124A1 (de) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6343232B1 (en) | 1966-08-19 | 2002-01-29 | Mower Chf Treatment Irrevocable Trust | Augmentation of muscle contractility by biphasic stimulation |
US9289618B1 (en) | 1996-01-08 | 2016-03-22 | Impulse Dynamics Nv | Electrical muscle controller |
WO2001024871A2 (en) * | 1999-10-04 | 2001-04-12 | Impulse Dynamics N.V. | Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue |
US8825152B2 (en) | 1996-01-08 | 2014-09-02 | Impulse Dynamics, N.V. | Modulation of intracellular calcium concentration using non-excitatory electrical signals applied to the tissue |
US7167748B2 (en) | 1996-01-08 | 2007-01-23 | Impulse Dynamics Nv | Electrical muscle controller |
US8321013B2 (en) | 1996-01-08 | 2012-11-27 | Impulse Dynamics, N.V. | Electrical muscle controller and pacing with hemodynamic enhancement |
US9713723B2 (en) | 1996-01-11 | 2017-07-25 | Impulse Dynamics Nv | Signal delivery through the right ventricular septum |
US6415178B1 (en) * | 1996-09-16 | 2002-07-02 | Impulse Dynamics N.V. | Fencing of cardiac muscles |
US7908003B1 (en) | 1996-08-19 | 2011-03-15 | Mr3 Medical Llc | System and method for treating ischemia by improving cardiac efficiency |
US6337995B1 (en) | 1996-08-19 | 2002-01-08 | Mower Chf Treatment Irrevocable Trust | Atrial sensing and multiple site stimulation as intervention for atrial fibrillation |
US6341235B1 (en) | 1996-08-19 | 2002-01-22 | Mower Chf Treatment Irrevocable Trust | Augmentation of electrical conduction and contractility by biphasic cardiac pacing administered via the cardiac blood pool |
US7840264B1 (en) | 1996-08-19 | 2010-11-23 | Mr3 Medical, Llc | System and method for breaking reentry circuits by cooling cardiac tissue |
US6411847B1 (en) | 1996-08-19 | 2002-06-25 | Morton M. Mower | Apparatus for applying cyclic pacing at an average rate just above the intrinsic heart rate |
US8447399B2 (en) | 1996-08-19 | 2013-05-21 | Mr3 Medical, Llc | System and method for managing detrimental cardiac remodeling |
US6295470B1 (en) * | 1996-08-19 | 2001-09-25 | The Mower Family Chf Treatment Irrevocable Trust | Antitachycardial pacing |
JP4523169B2 (ja) | 1999-02-04 | 2010-08-11 | プルリステム リミテッド | 造血幹細胞および/または前駆細胞を維持および増加するための方法および装置 |
US6411845B1 (en) | 1999-03-04 | 2002-06-25 | Mower Chf Treatment Irrevocable Trust | System for multiple site biphasic stimulation to revert ventricular arrhythmias |
US8019421B2 (en) | 1999-03-05 | 2011-09-13 | Metacure Limited | Blood glucose level control |
US8346363B2 (en) | 1999-03-05 | 2013-01-01 | Metacure Limited | Blood glucose level control |
WO2006073671A1 (en) | 2004-12-09 | 2006-07-13 | Impulse Dynamics Nv | Protein activity modification |
US8700161B2 (en) | 1999-03-05 | 2014-04-15 | Metacure Limited | Blood glucose level control |
US9101765B2 (en) | 1999-03-05 | 2015-08-11 | Metacure Limited | Non-immediate effects of therapy |
US8666495B2 (en) | 1999-03-05 | 2014-03-04 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
US6993385B1 (en) | 1999-10-25 | 2006-01-31 | Impulse Dynamics N.V. | Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof |
WO2001030445A1 (en) | 1999-10-25 | 2001-05-03 | Impulse Dynamics N.V. | Cardiac contractility modulation device having anti-arrhythmic capabilities and a method of operating thereof |
WO2002065896A2 (en) * | 2001-02-20 | 2002-08-29 | Case Western Reserve University | Systems and methods for reversibly blocking nerve activity |
USRE45718E1 (en) * | 2001-02-20 | 2015-10-06 | Boston Scientific Corporation | Systems and methods for reversibly blocking nerve activity |
US7860570B2 (en) * | 2002-06-20 | 2010-12-28 | Boston Scientific Neuromodulation Corporation | Implantable microstimulators and methods for unidirectional propagation of action potentials |
CN100538292C (zh) | 2003-02-10 | 2009-09-09 | N-特莱格有限公司 | 数字化器的触摸检测 |
US11439815B2 (en) | 2003-03-10 | 2022-09-13 | Impulse Dynamics Nv | Protein activity modification |
EP1606011B1 (de) | 2003-03-10 | 2015-08-19 | Impulse Dynamics N.V. | Gerät zur abgabe von elektrischen signalen zur modifizierung der genexpression in herzgewebe |
US8027721B2 (en) | 2003-03-24 | 2011-09-27 | Physio-Control, Inc. | Balanced charge waveform for transcutaneous pacing |
US8792985B2 (en) | 2003-07-21 | 2014-07-29 | Metacure Limited | Gastrointestinal methods and apparatus for use in treating disorders and controlling blood sugar |
US20050055057A1 (en) * | 2003-09-05 | 2005-03-10 | Mirowski Famliy Ventures, L.L.C. | Method and apparatus for providing ipselateral therapy |
US11779768B2 (en) | 2004-03-10 | 2023-10-10 | Impulse Dynamics Nv | Protein activity modification |
WO2006119467A2 (en) | 2005-05-04 | 2006-11-09 | Impulse Dynamics Nv | Protein activity modification |
US8352031B2 (en) | 2004-03-10 | 2013-01-08 | Impulse Dynamics Nv | Protein activity modification |
US9821158B2 (en) | 2005-02-17 | 2017-11-21 | Metacure Limited | Non-immediate effects of therapy |
WO2006097934A2 (en) | 2005-03-18 | 2006-09-21 | Metacure Limited | Pancreas lead |
US7877136B1 (en) * | 2007-09-28 | 2011-01-25 | Boston Scientific Neuromodulation Corporation | Enhancement of neural signal transmission through damaged neural tissue via hyperpolarizing electrical stimulation current |
US8934975B2 (en) | 2010-02-01 | 2015-01-13 | Metacure Limited | Gastrointestinal electrical therapy |
US10940318B2 (en) | 2014-06-17 | 2021-03-09 | Morton M. Mower | Method and apparatus for electrical current therapy of biological tissue |
GB2553089B (en) | 2016-08-15 | 2018-11-21 | Ipulse Medical Ltd | Device for providing pain relief |
KR102627205B1 (ko) | 2018-11-20 | 2024-01-18 | 뉴에너치 인크 | 역 관계를 갖는 주파수 및 피크 전압을 적용하는 전기 자극 장치 |
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GB1459397A (en) * | 1973-03-22 | 1976-12-22 | Biopulse Co Ltd | Apparatus for treating organisms by applying an electrical signal thereto |
US3924641A (en) * | 1974-08-19 | 1975-12-09 | Axotronics Inc | Bi-phasic current stimulation system |
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US4019519A (en) * | 1975-07-08 | 1977-04-26 | Neuvex, Inc. | Nerve stimulating device |
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US4222386A (en) * | 1979-03-26 | 1980-09-16 | Smolnikov Leonid E | Method for stimulating cardiac action by means of implanted _electrocardiostimulator and implantable electrocardiostimulator for effecting same |
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FR2763247B1 (fr) * | 1997-05-16 | 2000-02-18 | Ela Medical Sa | Dispositif medical implantable actif, notamment stimulateur cardiaque, defibrillateur et/ou cardioverteur a reduction des episodes d'arythmie, notamment d'arythmie auriculaire |
-
1998
- 1998-01-16 US US09/008,636 patent/US6136019A/en not_active Expired - Lifetime
-
1999
- 1999-01-13 IL IL13732199A patent/IL137321A/xx unknown
- 1999-01-13 EP EP99903109A patent/EP1064048B1/de not_active Expired - Lifetime
- 1999-01-13 AT AT99903109T patent/ATE279958T1/de not_active IP Right Cessation
- 1999-01-13 ID IDW20001374A patent/ID26205A/id unknown
- 1999-01-13 AP APAP/P/2002/002486A patent/AP2002002486A0/en unknown
- 1999-01-13 CA CA002318101A patent/CA2318101C/en not_active Expired - Fee Related
- 1999-01-13 DK DK99903109T patent/DK1064048T3/da active
- 1999-01-13 GE GEAP19995504A patent/GEP20022789B/en unknown
- 1999-01-13 HU HU0102503A patent/HUP0102503A2/hu unknown
- 1999-01-13 WO PCT/US1999/000879 patent/WO1999036124A1/en active IP Right Grant
- 1999-01-13 AU AU23211/99A patent/AU2321199A/en not_active Abandoned
- 1999-01-13 CZ CZ20002634A patent/CZ299883B6/cs not_active IP Right Cessation
- 1999-01-13 SK SK1073-2000A patent/SK286698B6/sk not_active IP Right Cessation
- 1999-01-13 DE DE69921309T patent/DE69921309T2/de not_active Expired - Fee Related
- 1999-01-13 EA EA200000764A patent/EA003163B1/ru not_active IP Right Cessation
- 1999-01-13 NZ NZ505749A patent/NZ505749A/en not_active Application Discontinuation
- 1999-01-13 ES ES99903109T patent/ES2229670T3/es not_active Expired - Lifetime
-
2000
- 2000-07-20 NO NO20003732A patent/NO20003732L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
SK10732000A3 (sk) | 2001-01-18 |
NO20003732D0 (no) | 2000-07-20 |
CZ20002634A3 (cs) | 2001-04-11 |
GEP20022789B (en) | 2002-09-25 |
CA2318101A1 (en) | 1999-07-22 |
HUP0102503A2 (hu) | 2001-10-28 |
CA2318101C (en) | 2003-12-02 |
IL137321A0 (en) | 2001-07-24 |
US6136019A (en) | 2000-10-24 |
SK286698B6 (sk) | 2009-03-05 |
DK1064048T3 (da) | 2005-02-14 |
EA003163B1 (ru) | 2003-02-27 |
NO20003732L (no) | 2000-08-29 |
ATE279958T1 (de) | 2004-11-15 |
CZ299883B6 (cs) | 2008-12-17 |
AP2002002486A0 (en) | 2002-06-30 |
WO1999036124A1 (en) | 1999-07-22 |
EP1064048A1 (de) | 2001-01-03 |
ID26205A (id) | 2000-12-07 |
DE69921309T2 (de) | 2005-10-13 |
EA200000764A1 (ru) | 2001-10-22 |
EP1064048B1 (de) | 2004-10-20 |
NZ505749A (en) | 2003-07-25 |
AU2321199A (en) | 1999-08-02 |
ES2229670T3 (es) | 2005-04-16 |
IL137321A (en) | 2005-09-25 |
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