DE69918260D1 - Methoden zur Identifizierung und Validierung von funktionellen Zielen mittels Intrameren oder in vivo Selektion - Google Patents
Methoden zur Identifizierung und Validierung von funktionellen Zielen mittels Intrameren oder in vivo SelektionInfo
- Publication number
- DE69918260D1 DE69918260D1 DE69918260T DE69918260T DE69918260D1 DE 69918260 D1 DE69918260 D1 DE 69918260D1 DE 69918260 T DE69918260 T DE 69918260T DE 69918260 T DE69918260 T DE 69918260T DE 69918260 D1 DE69918260 D1 DE 69918260D1
- Authority
- DE
- Germany
- Prior art keywords
- intramers
- validation
- identification
- methods
- vivo selection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000010200 validation analysis Methods 0.000 title abstract 2
- 238000001727 in vivo Methods 0.000 title 1
- 230000003834 intracellular effect Effects 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99106453A EP1041144B1 (de) | 1999-03-29 | 1999-03-29 | Methoden zur Identifizierung und Validierung von funktionellen Zielen mittels Intrameren oder in vivo Selektion |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69918260D1 true DE69918260D1 (de) | 2004-07-29 |
| DE69918260T2 DE69918260T2 (de) | 2005-07-14 |
Family
ID=8237883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69918260T Expired - Fee Related DE69918260T2 (de) | 1999-03-29 | 1999-03-29 | Methoden zur Identifizierung und Validierung von funktionellen Zielen mittels Intrameren oder in vivo Selektion |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070287153A1 (de) |
| EP (2) | EP1041144B1 (de) |
| JP (1) | JP2002539825A (de) |
| AT (1) | ATE269897T1 (de) |
| AU (1) | AU3558000A (de) |
| CA (1) | CA2365297A1 (de) |
| DE (1) | DE69918260T2 (de) |
| WO (1) | WO2000058455A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1223216A1 (de) * | 2000-12-30 | 2002-07-17 | NascaCell GmbH | Intrazelluläre Nukleinsäureinhibitoren kleiner Guaninnukleotid-Austauschfaktoren |
| WO2011125852A1 (ja) * | 2010-04-01 | 2011-10-13 | Ｎｅｃソフト株式会社 | 核酸構築物、それを用いた複合体の製造方法およびスクリーニング方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5707796A (en) * | 1990-06-11 | 1998-01-13 | Nexstar Pharmaceuticals, Inc. | Method for selecting nucleic acids on the basis of structure |
| DE69610310T2 (de) * | 1995-06-02 | 2001-03-15 | M&E Biotech A/S, Horsholm | Verfahren zur identifikation von biologisch aktiven peptiden und nukleinsäuren |
| US6187757B1 (en) * | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
| US6153380A (en) * | 1996-01-23 | 2000-11-28 | Rigel Pharmaceuticals, Inc. | Methods for screening for transdominant intracellular effector peptides and RNA molecules |
| WO1997039722A2 (en) * | 1996-04-25 | 1997-10-30 | T Cell Sciences, Inc. | Method of isolating regulators of t cell activation |
| US6605429B1 (en) * | 1997-01-23 | 2003-08-12 | Immusol, Incorporated | Gene functional analysis and discovery using randomized or target-specific ribozyme gene vector libraries |
-
1999
- 1999-03-29 EP EP99106453A patent/EP1041144B1/de not_active Expired - Lifetime
- 1999-03-29 DE DE69918260T patent/DE69918260T2/de not_active Expired - Fee Related
- 1999-03-29 AT AT99106453T patent/ATE269897T1/de not_active IP Right Cessation
-
2000
- 2000-03-28 AU AU35580/00A patent/AU3558000A/en not_active Abandoned
- 2000-03-28 EP EP00914168A patent/EP1165770A2/de not_active Withdrawn
- 2000-03-28 CA CA002365297A patent/CA2365297A1/en not_active Abandoned
- 2000-03-28 WO PCT/EP2000/002727 patent/WO2000058455A2/en not_active Ceased
- 2000-03-28 JP JP2000608736A patent/JP2002539825A/ja active Pending
-
2006
- 2006-05-25 US US11/440,907 patent/US20070287153A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE269897T1 (de) | 2004-07-15 |
| EP1041144B1 (de) | 2004-06-23 |
| US20070287153A1 (en) | 2007-12-13 |
| AU3558000A (en) | 2000-10-16 |
| DE69918260T2 (de) | 2005-07-14 |
| EP1165770A2 (de) | 2002-01-02 |
| JP2002539825A (ja) | 2002-11-26 |
| WO2000058455A2 (en) | 2000-10-05 |
| CA2365297A1 (en) | 2000-10-05 |
| WO2000058455A3 (en) | 2001-01-04 |
| EP1041144A1 (de) | 2000-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |