DE69916131D1 - Nicht-thrombogene, silylmodifizierte heparinbeschichtungszusammensetzung und verwendungen - Google Patents

Nicht-thrombogene, silylmodifizierte heparinbeschichtungszusammensetzung und verwendungen

Info

Publication number
DE69916131D1
DE69916131D1 DE69916131T DE69916131T DE69916131D1 DE 69916131 D1 DE69916131 D1 DE 69916131D1 DE 69916131 T DE69916131 T DE 69916131T DE 69916131 T DE69916131 T DE 69916131T DE 69916131 D1 DE69916131 D1 DE 69916131D1
Authority
DE
Germany
Prior art keywords
silylmodified
thrombogen
heparine
coating composition
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69916131T
Other languages
English (en)
Other versions
DE69916131T2 (de
Inventor
Ray Tsang
Shigemasa Osaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covidien LP
Original Assignee
Innerdyne Inc
Innerdyne Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innerdyne Inc, Innerdyne Medical Inc filed Critical Innerdyne Inc
Application granted granted Critical
Publication of DE69916131D1 publication Critical patent/DE69916131D1/de
Publication of DE69916131T2 publication Critical patent/DE69916131T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/60—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule in which all the silicon atoms are connected by linkages other than oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials For Medical Uses (AREA)
DE69916131T 1997-12-22 1999-01-08 Nicht-thrombogene, silylmodifizierte heparinbeschichtungszusammensetzung und verwendungen Expired - Lifetime DE69916131T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6837497P 1997-12-22 1997-12-22
US09/159,276 US5955588A (en) 1997-12-22 1998-09-22 Non-thrombogenic coating composition and methods for using same
PCT/US1999/000450 WO2000040619A1 (en) 1997-12-22 1999-01-08 Non-thrombogenic coating composition and methods for using same

Publications (2)

Publication Number Publication Date
DE69916131D1 true DE69916131D1 (de) 2004-05-06
DE69916131T2 DE69916131T2 (de) 2005-02-17

Family

ID=27371324

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69916131T Expired - Lifetime DE69916131T2 (de) 1997-12-22 1999-01-08 Nicht-thrombogene, silylmodifizierte heparinbeschichtungszusammensetzung und verwendungen

Country Status (6)

Country Link
US (1) US5955588A (de)
EP (1) EP1159302B1 (de)
JP (1) JP4395562B2 (de)
DE (1) DE69916131T2 (de)
ES (1) ES2214838T3 (de)
WO (1) WO2000040619A1 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6179817B1 (en) * 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US6558798B2 (en) 1995-02-22 2003-05-06 Scimed Life Systems, Inc. Hydrophilic coating and substrates coated therewith having enhanced durability and lubricity
DE19702402A1 (de) * 1997-01-24 1998-07-30 Beyersdorf Friedhelm Univ Prof Verfahren und Reperfusionsvorrichtung
US6656922B2 (en) * 1998-05-28 2003-12-02 Mediplex Corporation, Korea Oral delivery of macromolecules
US6533766B1 (en) 1998-07-24 2003-03-18 Therox, Inc. Coating medical device surfaces for delivering gas-supersaturated fluids
US6248127B1 (en) * 1998-08-21 2001-06-19 Medtronic Ave, Inc. Thromboresistant coated medical device
US6921811B2 (en) * 1998-09-22 2005-07-26 Biosurface Engineering Technologies, Inc. Bioactive coating composition and methods
US6342591B1 (en) 1998-09-22 2002-01-29 Biosurface Engineering Technologies, Inc. Amphipathic coating for modulating cellular adhesion composition and methods
US6596699B2 (en) 1998-09-22 2003-07-22 Biosurface Engineering Technologies, Inc. Nucleic acid coating compositions and methods
US6733513B2 (en) 1999-11-04 2004-05-11 Advanced Bioprosthetic Surfaces, Ltd. Balloon catheter having metal balloon and method of making same
US10172730B2 (en) 1999-11-19 2019-01-08 Vactronix Scientific, Llc Stents with metallic covers and methods of making same
US8458879B2 (en) 2001-07-03 2013-06-11 Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. Method of fabricating an implantable medical device
US7235092B2 (en) 1999-11-19 2007-06-26 Advanced Bio Prosthetic Surfaces, Ltd. Guidewires and thin film catheter-sheaths and method of making same
US7736687B2 (en) 2006-01-31 2010-06-15 Advance Bio Prosthetic Surfaces, Ltd. Methods of making medical devices
US6849085B2 (en) 1999-11-19 2005-02-01 Advanced Bio Prosthetic Surfaces, Ltd. Self-supporting laminated films, structural materials and medical devices manufactured therefrom and method of making same
US6537310B1 (en) 1999-11-19 2003-03-25 Advanced Bio Prosthetic Surfaces, Ltd. Endoluminal implantable devices and method of making same
US6379383B1 (en) 1999-11-19 2002-04-30 Advanced Bio Prosthetic Surfaces, Ltd. Endoluminal device exhibiting improved endothelialization and method of manufacture thereof
US7195641B2 (en) 1999-11-19 2007-03-27 Advanced Bio Prosthetic Surfaces, Ltd. Valvular prostheses having metal or pseudometallic construction and methods of manufacture
US6936066B2 (en) * 1999-11-19 2005-08-30 Advanced Bio Prosthetic Surfaces, Ltd. Complaint implantable medical devices and methods of making same
US7300457B2 (en) 1999-11-19 2007-11-27 Advanced Bio Prosthetic Surfaces, Ltd. Self-supporting metallic implantable grafts, compliant implantable medical devices and methods of making same
US6613432B2 (en) * 1999-12-22 2003-09-02 Biosurface Engineering Technologies, Inc. Plasma-deposited coatings, devices and methods
US6695865B2 (en) 2000-03-20 2004-02-24 Advanced Bio Prosthetic Surfaces, Ltd. Embolic protection device
GB0009771D0 (en) * 2000-04-19 2000-06-07 Angiomed Ag Method for linking nucleic acids
US9566148B2 (en) 2000-05-12 2017-02-14 Vactronix Scientific, Inc. Self-supporting laminated films, structural materials and medical devices manufactured therefrom and methods of making same
US8632583B2 (en) 2011-05-09 2014-01-21 Palmaz Scientific, Inc. Implantable medical device having enhanced endothelial migration features and methods of making the same
EP1328279B1 (de) * 2000-09-20 2009-08-26 Aquamed Technologies, Inc. Zusammensetzungen aus lignin und verfahren zu ihrer herstellung und verwendung
KR100378109B1 (ko) * 2000-10-24 2003-03-29 주식회사 메디프렉스 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도
US7807210B1 (en) 2000-10-31 2010-10-05 Advanced Cardiovascular Systems, Inc. Hemocompatible polymers on hydrophobic porous polymers
AU2002233936A1 (en) 2000-11-07 2002-05-21 Advanced Bio Prosthetic Surfaces, Ltd. Endoluminal stent, self-fupporting endoluminal graft and methods of making same
US7297343B2 (en) * 2001-07-31 2007-11-20 Biosurface Engineering Technologies, Inc. Bioactive medical films
US20070173460A1 (en) * 2001-09-20 2007-07-26 Oculus Innovative Sciences, Inc. Compositions comprising lignin and methods of making and using the same
US6558409B1 (en) 2001-09-28 2003-05-06 Tyco Healthcare Group Lp Plasma treated surgical needles and methods for their manufacture
US7294357B2 (en) * 2001-09-28 2007-11-13 Tyco Healthcare Group Lp Plasma coated sutures
US20030148017A1 (en) * 2001-12-07 2003-08-07 Olli Tuominen Copolymer coating for a hydrophobic membrane
WO2004002469A1 (de) * 2002-06-29 2004-01-08 Aquanova German Solubilisate Technologies (Agt) Gmbh Isoflavonkonzentrate sowie verfahren zu ihrer herstellung
US7166574B2 (en) 2002-08-20 2007-01-23 Biosurface Engineering Technologies, Inc. Synthetic heparin-binding growth factor analogs
US7598224B2 (en) 2002-08-20 2009-10-06 Biosurface Engineering Technologies, Inc. Dual chain synthetic heparin-binding growth factor analogs
US7981862B2 (en) 2003-08-19 2011-07-19 Biosurface Engineering Technologies, Inc. Composition comprising BMP-2 amplifier/co-activator for enhancement of osteogenesis
US8227411B2 (en) 2002-08-20 2012-07-24 BioSurface Engineering Technologies, Incle FGF growth factor analogs
CA2499961C (en) 2002-09-26 2014-12-30 Advanced Bio Prosthetic Surfaces, Ltd. High strength vacuum deposited nitinol alloy films, medical thin film graft materials and method of making same
US8679517B2 (en) 2002-09-26 2014-03-25 Palmaz Scientific, Inc. Implantable materials having engineered surfaces made by vacuum deposition and method of making same
US8268340B2 (en) 2002-09-26 2012-09-18 Advanced Bio Prosthetic Surfaces, Ltd. Implantable materials having engineered surfaces and method of making same
AU2003272710B2 (en) 2002-09-26 2008-05-15 Vactronix Scientific, Llc Implantable materials having engineered surfaces and method of making same
US6702850B1 (en) * 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
US7468210B1 (en) * 2002-12-10 2008-12-23 Biosurface Engineering Technologies, Inc. Cross-linked heparin coatings and methods
CN101005812A (zh) 2003-05-07 2007-07-25 先进生物假体表面有限公司 可植入性金属移植物及其制造方法
US7414028B1 (en) 2004-02-04 2008-08-19 Biosurface Engineering Technologies, Inc. Growth factor analogs
US7528105B1 (en) 2004-02-10 2009-05-05 Biosurface Engineering Technologies Heterodimeric chain synthetic heparin-binding growth factor analogs
US20060024347A1 (en) * 2004-02-10 2006-02-02 Biosurface Engineering Technologies, Inc. Bioactive peptide coatings
US20080227696A1 (en) * 2005-02-22 2008-09-18 Biosurface Engineering Technologies, Inc. Single branch heparin-binding growth factor analogs
US7671012B2 (en) 2004-02-10 2010-03-02 Biosurface Engineering Technologies, Inc. Formulations and methods for delivery of growth factor analogs
WO2005082005A2 (en) 2004-02-20 2005-09-09 Biosurface Engineering Technologies, Inc., Et Al. Positive modulator of bone morphogenic protein-2
US20060093647A1 (en) * 2004-10-29 2006-05-04 Villafana Manuel A Multiple layer coating composition
US20070129666A1 (en) * 2005-11-22 2007-06-07 Barton David F System and method of modular integration of intravascular gas exchange catheter with respiratory monitor and ventilator
US8021677B2 (en) * 2006-05-12 2011-09-20 Gore Enterprise Holdings, Inc. Immobilized biologically active entities having a high degree of biological activity
US7820172B1 (en) 2006-06-01 2010-10-26 Biosurface Engineering Technologies, Inc. Laminin-derived multi-domain peptides
JP2010517638A (ja) * 2007-02-02 2010-05-27 トアニエ， インコーポレイテッド 腱および靱帯を修復するシステムおよび方法
US20100021538A1 (en) * 2008-02-29 2010-01-28 Youngro Byun Pharmaceutical compositions containing heparin derivatives
EP2310035B1 (de) 2008-06-16 2015-08-26 University Of Rochester Fibroblasten-wachstumsfaktor (fgf) analoga und ihre verwendungen
US20100316787A1 (en) * 2009-06-12 2010-12-16 Greatbatch Ltd. Biomimetic Coating Method
JP5688791B2 (ja) * 2010-05-11 2015-03-25 グレイトバッチ リミテッドＧｒｅａｔｂａｔｃｈ Ｌｔｄ． コーティングのための表面修飾
AU2011292012B2 (en) 2010-08-17 2014-05-08 Palmaz Scientific, Inc. Transluminal cardiac ball valve and method for deployment thereof
EP2624776B1 (de) 2010-10-05 2021-04-28 Emory University Vorrichtungen und systeme zur verbesserung des zugangs zu herz- und gefässkammern
US8728563B2 (en) 2011-05-03 2014-05-20 Palmaz Scientific, Inc. Endoluminal implantable surfaces, stents, and grafts and method of making same
US20130046375A1 (en) 2011-08-17 2013-02-21 Meng Chen Plasma modified medical devices and methods
EP2941249A4 (de) * 2013-01-07 2016-09-28 Univ Maryland Biokompatible beschichtungszusammensetzungen
US9339770B2 (en) 2013-11-19 2016-05-17 Applied Membrane Technologies, Inc. Organosiloxane films for gas separations
JP6939706B2 (ja) * 2018-05-30 2021-09-22 信越化学工業株式会社 カーボネート基含有シラン化合物およびその製造方法
CN114191621B (zh) * 2020-09-18 2022-08-19 西华师范大学 一种多层表面结构的抗菌防粘连医用聚丙烯补片及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5338770A (en) * 1988-06-08 1994-08-16 Cardiopulmonics, Inc. Gas permeable thrombo-resistant coatings and methods of manufacture
DE69201193T2 (de) * 1991-05-31 1995-09-07 Baxter International Inc., Deerfield, Ill. Schaumdrückende gerinnungsbeständige beschichtung.
US5463010A (en) * 1993-11-12 1995-10-31 Surface Engineering Technologies, Division Of Innerdyne, Inc. Hydrocyclosiloxane membrane prepared by plasma polymerization process

Also Published As

Publication number Publication date
EP1159302A4 (de) 2003-07-16
ES2214838T3 (es) 2004-09-16
DE69916131T2 (de) 2005-02-17
JP4395562B2 (ja) 2010-01-13
EP1159302A1 (de) 2001-12-05
EP1159302B1 (de) 2004-03-31
US5955588A (en) 1999-09-21
JP2002534177A (ja) 2002-10-15
WO2000040619A1 (en) 2000-07-13

Similar Documents

Publication Publication Date Title
DE69916131D1 (de) Nicht-thrombogene, silylmodifizierte heparinbeschichtungszusammensetzung und verwendungen
NL300295I1 (nl) 3,3-Diarylpropylaminen, de toepassing en bereiding hiervan
ID24703A (id) Kuinolon antimikroba, komposisi dan penggunaannya
DE59813068D1 (de) Beschichtungsmaterial
DE69812389D1 (de) Beschichtetes wälzlager
DE69724224D1 (de) Anti-fouling Trennschicht-Zusammensetzung und beschichtete Gegenstände
DE69911065D1 (de) Alkoxyacrylamide photochrome beschichtungszusammensetzung und photochrome gegenstände
DE69705979D1 (de) Wässrige Besichtungszusammentsetzung
ID19824A (id) Turunan-turunan ditiolan, pembuatannya dan pengaruh terapinya
DE69926237D1 (de) Beschichtungszusammensetzung
DE69703153D1 (de) Formanpassungsfähiges, prägbares retroreflektierendes bahnenmaterial
DE69705347D1 (de) Überzugsmittel
DE69711284D1 (de) Bindemittelzusammensetzung und wässrige Überzugsmittelzusammensetzung
NO980985L (no) Teppebeleggsblanding
DE69817865D1 (de) Pulverbeschichtungsanlage
BR9500473A (pt) Composição sólida,composição de revestimento em pó e revestimento reticulado
DE69805984D1 (de) Beschichtungs-, klebe- und dichtmittel zusammensetzungen
ID24196A (id) Komposisi dan penggunaan
DE69725265D1 (de) Pulverlack
DE69807911D1 (de) Vernetzbare zusammensetzung
GB9712317D0 (en) Composition, compound and use
DE69919480D1 (de) Beschichtungszusammensetzung
ID29052A (id) Turunan-turunan 3,3-biarilpiperidina dan 2,2-biarilmorfolina
DE59810590D1 (de) Polymere metallbeschichtung
GB9718876D0 (en) Compound,composition and use

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TYCO HEALTHCARE GROUP LP, MANSFIELD, MASS., US