DE69911252D1 - Verfahren zur herstellung von tricyclischen verbindungen mit antihistaminischer wirkung - Google Patents
Verfahren zur herstellung von tricyclischen verbindungen mit antihistaminischer wirkungInfo
- Publication number
- DE69911252D1 DE69911252D1 DE69911252T DE69911252T DE69911252D1 DE 69911252 D1 DE69911252 D1 DE 69911252D1 DE 69911252 T DE69911252 T DE 69911252T DE 69911252 T DE69911252 T DE 69911252T DE 69911252 D1 DE69911252 D1 DE 69911252D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- tricyclic compounds
- antihistaminic effect
- antihistaminic
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001387 anti-histamine Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US216170 | 1980-12-15 | ||
| US21617098A | 1998-12-18 | 1998-12-18 | |
| PCT/US1999/027936 WO2000037457A1 (en) | 1998-12-18 | 1999-12-16 | Process for preparing tricyclic compounds having antihistaminic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69911252D1 true DE69911252D1 (de) | 2003-10-16 |
| DE69911252T2 DE69911252T2 (de) | 2004-07-01 |
Family
ID=22805995
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69911252T Expired - Lifetime DE69911252T2 (de) | 1998-12-18 | 1999-12-16 | Verfahren zur herstellung von tricyclischen verbindungen mit antihistaminischer wirkung |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1140899B1 (de) |
| JP (1) | JP4558942B2 (de) |
| CN (1) | CN1257166C (de) |
| AR (1) | AR021715A1 (de) |
| AT (1) | ATE249453T1 (de) |
| AU (1) | AU2157100A (de) |
| CA (1) | CA2355050C (de) |
| CO (1) | CO5251403A1 (de) |
| DE (1) | DE69911252T2 (de) |
| ES (1) | ES2207329T3 (de) |
| HK (1) | HK1039334B (de) |
| MY (1) | MY119697A (de) |
| PE (1) | PE20001334A1 (de) |
| TW (1) | TWI225056B (de) |
| WO (1) | WO2000037457A1 (de) |
| ZA (1) | ZA200104631B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20012308A1 (it) * | 2001-11-05 | 2003-05-05 | Zambon Spa | Processo per la preparazione dell'estere etilico dell'acido 4-(8-cloro-5,6-diidro-11h-benzo-5,67-cicloepta-1,2-b-piridin-11-ilidene)-1-piper |
| CN106478595B (zh) * | 2016-09-18 | 2019-05-21 | 西安交通大学 | 氯雷他定晶型及其制备方法和用途 |
| CN113135899B (zh) * | 2021-06-21 | 2021-11-23 | 北京鑫开元医药科技有限公司 | 苯并环庚烷并吡啶化合物、其制备方法及其用途 |
| CN113135893B (zh) * | 2021-06-21 | 2022-02-11 | 北京鑫开元医药科技有限公司 | 苯并环庚烷并吡啶化合物、其制备方法及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| US4355036A (en) * | 1980-06-19 | 1982-10-19 | Schering Corporation | Tricyclic-substituted piperidine antihistamines |
| DE3677842D1 (de) * | 1985-05-13 | 1991-04-11 | Schering Corp | Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln. |
-
1999
- 1999-12-16 AT AT99965895T patent/ATE249453T1/de not_active IP Right Cessation
- 1999-12-16 WO PCT/US1999/027936 patent/WO2000037457A1/en active IP Right Grant
- 1999-12-16 TW TW088122098A patent/TWI225056B/zh not_active IP Right Cessation
- 1999-12-16 PE PE1999001278A patent/PE20001334A1/es not_active Application Discontinuation
- 1999-12-16 ES ES99965895T patent/ES2207329T3/es not_active Expired - Lifetime
- 1999-12-16 DE DE69911252T patent/DE69911252T2/de not_active Expired - Lifetime
- 1999-12-16 CO CO99078840A patent/CO5251403A1/es not_active Application Discontinuation
- 1999-12-16 AR ARP990106458A patent/AR021715A1/es not_active Application Discontinuation
- 1999-12-16 JP JP2000589529A patent/JP4558942B2/ja not_active Expired - Fee Related
- 1999-12-16 CN CNB998159670A patent/CN1257166C/zh not_active Expired - Lifetime
- 1999-12-16 EP EP99965895A patent/EP1140899B1/de not_active Expired - Lifetime
- 1999-12-16 AU AU21571/00A patent/AU2157100A/en not_active Abandoned
- 1999-12-16 CA CA002355050A patent/CA2355050C/en not_active Expired - Lifetime
- 1999-12-17 MY MYPI99005547A patent/MY119697A/en unknown
-
2001
- 2001-06-06 ZA ZA200104631A patent/ZA200104631B/en unknown
-
2002
- 2002-02-05 HK HK02100883.8A patent/HK1039334B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HK1039334A1 (en) | 2002-04-19 |
| CA2355050C (en) | 2007-04-17 |
| CN1334810A (zh) | 2002-02-06 |
| HK1039334B (zh) | 2003-12-05 |
| WO2000037457A1 (en) | 2000-06-29 |
| ZA200104631B (en) | 2002-09-06 |
| EP1140899A1 (de) | 2001-10-10 |
| CO5251403A1 (es) | 2003-02-28 |
| TWI225056B (en) | 2004-12-11 |
| MY119697A (en) | 2005-06-30 |
| DE69911252T2 (de) | 2004-07-01 |
| EP1140899B1 (de) | 2003-09-10 |
| PE20001334A1 (es) | 2000-12-01 |
| AR021715A1 (es) | 2002-07-31 |
| CN1257166C (zh) | 2006-05-24 |
| ES2207329T3 (es) | 2004-05-16 |
| AU2157100A (en) | 2000-07-12 |
| CA2355050A1 (en) | 2000-06-29 |
| ATE249453T1 (de) | 2003-09-15 |
| JP4558942B2 (ja) | 2010-10-06 |
| JP2002533334A (ja) | 2002-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |