DE69902821D1 - 4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung - Google Patents

4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung

Info

Publication number
DE69902821D1
DE69902821D1 DE69902821T DE69902821T DE69902821D1 DE 69902821 D1 DE69902821 D1 DE 69902821D1 DE 69902821 T DE69902821 T DE 69902821T DE 69902821 T DE69902821 T DE 69902821T DE 69902821 D1 DE69902821 D1 DE 69902821D1
Authority
DE
Germany
Prior art keywords
substituted
mammal
aromatic ring
nitrogen form
heterocyclic aromatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69902821T
Other languages
English (en)
Other versions
DE69902821T2 (de
Inventor
D Heindel
S Whittemore
Christophe Guillon
D Rapp
D Laskin
E Mcneel
E Heck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Buckman Laboratories International Inc
Original Assignee
Buckman Laboratories International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Buckman Laboratories International Inc filed Critical Buckman Laboratories International Inc
Publication of DE69902821D1 publication Critical patent/DE69902821D1/de
Application granted granted Critical
Publication of DE69902821T2 publication Critical patent/DE69902821T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DE69902821T 1998-11-30 1999-11-30 4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung Expired - Fee Related DE69902821T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11033698P 1998-11-30 1998-11-30
PCT/US1999/028174 WO2000032603A1 (en) 1998-11-30 1999-11-30 4'-substituted-4',5'-dihydropsoralens and therapeutical uses thereof

Publications (2)

Publication Number Publication Date
DE69902821D1 true DE69902821D1 (de) 2002-10-10
DE69902821T2 DE69902821T2 (de) 2003-01-09

Family

ID=22332461

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69902821T Expired - Fee Related DE69902821T2 (de) 1998-11-30 1999-11-30 4'-substituierte-4',5'-dihydropsoralene und deren therapeutische verwendung

Country Status (10)

Country Link
US (1) US6177424B1 (de)
EP (1) EP1144417B1 (de)
AT (1) ATE223418T1 (de)
AU (1) AU1925500A (de)
CA (1) CA2352258A1 (de)
DE (1) DE69902821T2 (de)
ES (1) ES2183636T3 (de)
MX (1) MXPA01005363A (de)
PT (1) PT1144417E (de)
WO (1) WO2000032603A1 (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130568A (en) 1976-09-14 1978-12-19 Hoffmann-La Roche Inc. 8-Methoxypsoralen derivatives
US4124598A (en) 1976-10-20 1978-11-07 Hoffmann-La Roche Inc. Psoralens
US4196281A (en) * 1976-10-20 1980-04-01 Regents Of The University Of California Psoralens
US4294822A (en) 1980-07-29 1981-10-13 Thomas C. Elder, Inc. 5-Aminoalkyl-4,4,8-trialkylpsoralens
US4950770A (en) 1987-06-16 1990-08-21 Elder Pharmaceuticals, Inc. Psoralens aminomethylation
US5356929A (en) 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
US5216176A (en) * 1989-01-23 1993-06-01 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US5399719A (en) * 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US5625079A (en) * 1993-06-28 1997-04-29 Cerus Corporation Synthesizing psoralen compounds useful as intermediates

Also Published As

Publication number Publication date
EP1144417B1 (de) 2002-09-04
ATE223418T1 (de) 2002-09-15
AU1925500A (en) 2000-06-19
MXPA01005363A (es) 2004-04-21
PT1144417E (pt) 2002-12-31
DE69902821T2 (de) 2003-01-09
EP1144417A1 (de) 2001-10-17
WO2000032603A1 (en) 2000-06-08
CA2352258A1 (en) 2000-06-08
ES2183636T3 (es) 2003-03-16
US6177424B1 (en) 2001-01-23

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee