DE69840526D1 - Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens - Google Patents

Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens

Info

Publication number
DE69840526D1
DE69840526D1 DE69840526T DE69840526T DE69840526D1 DE 69840526 D1 DE69840526 D1 DE 69840526D1 DE 69840526 T DE69840526 T DE 69840526T DE 69840526 T DE69840526 T DE 69840526T DE 69840526 D1 DE69840526 D1 DE 69840526D1
Authority
DE
Germany
Prior art keywords
inflammatory agent
nitrogen monoxide
inhaled nitrogen
inhaled
monoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840526T
Other languages
English (en)
Inventor
Warren M Zapol
Kenneth D Bloch
Anthony Rosenzweig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26742873&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69840526(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by General Hospital Corp filed Critical General Hospital Corp
Application granted granted Critical
Publication of DE69840526D1 publication Critical patent/DE69840526D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
DE69840526T 1997-10-21 1998-10-19 Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens Expired - Lifetime DE69840526D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6292697P 1997-10-21 1997-10-21
US08/971,003 US6656452B1 (en) 1997-10-21 1997-11-14 Use of inhaled NO as anti-inflammatory agent
PCT/US1998/022044 WO1999020251A1 (en) 1997-10-21 1998-10-19 Use of inhaled no as anti-inflammatory agent

Publications (1)

Publication Number Publication Date
DE69840526D1 true DE69840526D1 (de) 2009-03-19

Family

ID=26742873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840526T Expired - Lifetime DE69840526D1 (de) 1997-10-21 1998-10-19 Verwendung von inhaliertem stickstoffmonoxid als entzündungshemmendes agens

Country Status (13)

Country Link
US (2) US6656452B1 (de)
EP (1) EP1073416B1 (de)
JP (1) JP2003532615A (de)
AR (1) AR015973A1 (de)
AT (1) ATE421874T1 (de)
AU (1) AU751853B2 (de)
CA (1) CA2309038C (de)
CY (1) CY1110228T1 (de)
DE (1) DE69840526D1 (de)
DK (1) DK1073416T3 (de)
ES (1) ES2319240T3 (de)
PT (1) PT1073416E (de)
WO (1) WO1999020251A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
US20030070674A1 (en) * 2001-10-12 2003-04-17 Bryan Perry Use of aerosolized compounds in the treatment of exercise induced pulmonary hemorrhage in an equine
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US7086397B2 (en) * 2002-02-16 2006-08-08 Graham Lindley Spruiell Patient usable emergency medical kit
US7091207B2 (en) * 2002-05-22 2006-08-15 Virginia Commonwealth University Method of treating myocardial infarction with PDE-5 inhibitors
CN1668316A (zh) * 2002-06-12 2005-09-14 梅瑟·格里斯海姆有限公司 含氙的解痉药
EP1515753A4 (de) * 2002-06-21 2009-07-15 Univ Pittsburgh Pharmazeutische verwendung von stickoxid, heme oxygenase-1 und produkte des heme-abbaus
SE0300971D0 (sv) * 2003-04-03 2003-04-03 Aga Ab Nitric oxide in treatment of inflammation
CA2536827C (en) * 2003-07-09 2014-09-16 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of nitrite salts for the treatment of cardiovascular conditions
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
US7829097B2 (en) * 2006-02-06 2010-11-09 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Use of HMGB1 for protection against ischemia reperfusion injury
WO2008063868A2 (en) * 2006-11-07 2008-05-29 The General Hospital Corporation Attenuation of vasoactive oxygen carrier-induced vasoconstriction
WO2008132239A1 (en) 2007-04-30 2008-11-06 Nnoxe Pharmaceutiques Inc Pharmaceutical composition comprising at least one thrombolytic agent (a) and at least one gas (b) selected from the group consisting of nitrous oxide, argon, xenon, helium, neon
WO2010049423A1 (en) * 2008-10-27 2010-05-06 Life Sciences Research Partners Vzw Effects of nitric oxide inhalation on long-term myocardial reperfusion injury
NO2440239T3 (de) 2009-06-09 2018-02-10
JP5581500B2 (ja) * 2010-03-10 2014-09-03 学校法人北里研究所 虚血再灌流障害軽減用治療剤および治療装置
EP3360557A3 (de) * 2010-12-03 2018-11-07 Geno LLC Stickoxidbehandlungen
WO2013052548A2 (en) 2011-10-03 2013-04-11 Nitric Generation Technologies Llc Apparatus and method for generating nitric oxide in controlled and accurate amounts
EP2776047A4 (de) 2011-11-07 2015-07-22 Gen Hospital Corp Behandlung von erythrozyten
JP2014141536A (ja) * 2014-05-16 2014-08-07 Kitasato Institute 虚血再灌流障害軽減用治療剤および治療装置
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
WO2023190532A1 (ja) * 2022-03-29 2023-10-05 康太郎 木田 横紋筋融解症を治療するための医薬組成物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5396882A (en) 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
US5536241A (en) * 1990-12-05 1996-07-16 The General Hospital Corporation Methods and devices for relaxing smooth muscle contractions
DE69133575T2 (de) * 1990-12-05 2008-04-17 The General Hospital Corp., Boston Verwendung von NO zur Behandlung der persistenten pulmonaren Hypertonie des Neugeborenen
US5570683A (en) * 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5427797A (en) 1993-04-06 1995-06-27 Brigham And Women's Hospital Systemic effects of nitric oxide inhalation
GB9320978D0 (en) 1993-10-12 1993-12-01 Higenbottam Timohy W Nitric oxide treatment
ES2149338T3 (es) 1993-11-02 2000-11-01 Us Health Utilizacion de compuestos que liberan oxido nitrico para la fabricacion de un medicamento destinado al tratamiento de lesiones por reperfusion isquemica.
US5521191A (en) 1994-10-17 1996-05-28 Washington University Method for treatment of arterial stenosis
US6063407A (en) 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5823180A (en) 1995-04-03 1998-10-20 The General Hospital Corporation Methods for treating pulmonary vasoconstriction and asthma
US5703073A (en) * 1995-04-19 1997-12-30 Nitromed, Inc. Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US5725492A (en) * 1996-03-04 1998-03-10 Cormedics Corp Extracorporeal circulation apparatus and method
ES2267141T3 (es) 1996-04-05 2007-03-01 The General Hospital Corporation Tratamiento de una hemoglobinopatia.
US6601580B1 (en) 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation

Also Published As

Publication number Publication date
WO1999020251A1 (en) 1999-04-29
EP1073416A4 (de) 2004-07-07
US6811768B2 (en) 2004-11-02
AR015973A1 (es) 2001-05-30
ES2319240T3 (es) 2009-05-05
US20040096523A1 (en) 2004-05-20
US6656452B1 (en) 2003-12-02
EP1073416B1 (de) 2009-01-28
PT1073416E (pt) 2009-03-17
CY1110228T1 (el) 2015-01-14
JP2003532615A (ja) 2003-11-05
AU751853B2 (en) 2002-08-29
EP1073416A1 (de) 2001-02-07
CA2309038A1 (en) 1999-04-29
ATE421874T1 (de) 2009-02-15
AU1101299A (en) 1999-05-10
DK1073416T3 (da) 2009-03-09
CA2309038C (en) 2009-04-21

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Legal Events

Date Code Title Description
8363 Opposition against the patent