DE69837348D1 - Verfahren zur inaktivierung von bakterien mit einbegriff von bakteriensporen - Google Patents

Verfahren zur inaktivierung von bakterien mit einbegriff von bakteriensporen

Info

Publication number
DE69837348D1
DE69837348D1 DE69837348T DE69837348T DE69837348D1 DE 69837348 D1 DE69837348 D1 DE 69837348D1 DE 69837348 T DE69837348 T DE 69837348T DE 69837348 T DE69837348 T DE 69837348T DE 69837348 D1 DE69837348 D1 DE 69837348D1
Authority
DE
Germany
Prior art keywords
bacteria
inactivating
spores
oil
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837348T
Other languages
English (en)
Other versions
DE69837348T2 (de
Inventor
James R Baker
D Craig Wright
Michael M Hayes
Tarek Hamouda
Joan Brisker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Publication of DE69837348D1 publication Critical patent/DE69837348D1/de
Application granted granted Critical
Publication of DE69837348T2 publication Critical patent/DE69837348T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/12Iodine, e.g. iodophors; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69837348T 1997-12-31 1998-12-28 Verfahren zur inaktivierung von bakterien mit einbegriff von bakteriensporen Expired - Lifetime DE69837348T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/002,228 US6015832A (en) 1997-12-31 1997-12-31 Methods of inactivating bacteria including bacterial spores
US2228 1997-12-31
PCT/US1998/027755 WO1999033459A1 (en) 1997-12-31 1998-12-28 Methods of inactivating bacteria including bacterial spores

Publications (2)

Publication Number Publication Date
DE69837348D1 true DE69837348D1 (de) 2007-04-26
DE69837348T2 DE69837348T2 (de) 2007-11-29

Family

ID=21699801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837348T Expired - Lifetime DE69837348T2 (de) 1997-12-31 1998-12-28 Verfahren zur inaktivierung von bakterien mit einbegriff von bakteriensporen

Country Status (10)

Country Link
US (1) US6015832A (de)
EP (1) EP1041978B1 (de)
JP (1) JP4683724B2 (de)
AT (1) ATE356549T1 (de)
AU (1) AU749817B2 (de)
CA (1) CA2316888C (de)
DE (1) DE69837348T2 (de)
HK (1) HK1031839A1 (de)
IL (1) IL137093A (de)
WO (1) WO1999033459A1 (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524592B2 (en) * 1997-10-17 2003-02-25 American Home Products Corporation Veterinary vaccines
US7390432B2 (en) * 1998-06-30 2008-06-24 Sandia Corporation Enhanced formulations for neutralization of chemical, biological and industrial toxants
US6723890B2 (en) 1998-06-30 2004-04-20 Sandia Corporation Concentrated formulations and methods for neutralizing chemical and biological toxants
US6506803B1 (en) * 1999-04-28 2003-01-14 Regents Of The University Of Michigan Methods of preventing and treating microbial infections
US6559189B2 (en) 1999-04-28 2003-05-06 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
US6635676B2 (en) * 1999-04-28 2003-10-21 Regents Of The University Of Michigan Non-toxic antimicrobial compositions and methods of use
US7655252B2 (en) * 1999-04-28 2010-02-02 The Regents Of The University Of Michigan Antimicrobial nanoemulsion compositions and methods
US7767216B2 (en) * 1999-04-28 2010-08-03 The Regents Of The University Of Michigan Antimicrobial compositions and methods of use
US20030059839A1 (en) * 2001-05-22 2003-03-27 Obiso Richard J. Method for detecting pathogens using immunoassays
US7314624B2 (en) * 2001-06-05 2008-01-01 The Regents Of The University Of Michigan Nanoemulsion vaccines
JP2010209109A (ja) * 2001-06-25 2010-09-24 Regents Of The Univ Of Michigan 抗微生物ナノエマルジョンの組成物および方法
CA2463710A1 (en) * 2001-10-19 2003-05-15 David S. Soane Anti-pathogenic air filtration media and air handling devices having protective capabilities against infectious airborne microorganisms
EP1446009A2 (de) * 2001-11-08 2004-08-18 Merck & Co., Inc. Verbindungen zur behandlung von anthrax
US20040087564A1 (en) * 2002-10-31 2004-05-06 Wright D. Craig Delivery composition and method
US20050208083A1 (en) * 2003-06-04 2005-09-22 Nanobio Corporation Compositions for inactivating pathogenic microorganisms, methods of making the compositons, and methods of use thereof
ATE378038T1 (de) * 2003-07-07 2007-11-15 Nares Ab Mikroemulsionen und ihre verwendung zur prävention von erkrankungen der atemwege
US8211448B2 (en) * 2003-07-07 2012-07-03 Nares Ab Microemulsions and its use for preventing airway diseases
US20050100601A1 (en) * 2003-11-07 2005-05-12 Viratox, L.L.C. Virucidal activities of cetylpyridinium chloride
WO2006076334A1 (en) * 2005-01-11 2006-07-20 Clean Earth Technologies, Llc Peracid/ peroxide composition and use thereof as an anti-microbial and a photosensitizer
CA2604392A1 (en) * 2005-04-11 2006-10-19 Nanobio Corporation Quaternary ammonium halides for treatment of infectious conditions
CA2618974C (en) * 2005-08-09 2014-01-28 Nanobio Corporation Nanoemulsion compositions having anti-inflammatory activity
US7797337B2 (en) * 2005-09-29 2010-09-14 Scenera Technologies, Llc Methods, systems, and computer program products for automatically associating data with a resource as metadata based on a characteristic of the resource
US9839685B2 (en) * 2006-04-13 2017-12-12 The Regents Of The University Of Michigan Methods of inducing human immunodeficiency virus-specific immune responses in a host comprising nasally administering compositions comprising a naonemulsion and recombinant GP120 immunogen
EP2012771A4 (de) * 2006-04-13 2010-01-27 Univ Michigan Nanoemulsionsimpfstoffe
US10138279B2 (en) 2006-04-13 2018-11-27 Regents Of The University Of Michigan Compositions and methods for Bacillus anthracis vaccination
US20080038295A1 (en) * 2006-04-13 2008-02-14 Regents Of The University Of Michigan Compositions and methods for orthopox virus vaccination
WO2008103416A1 (en) * 2007-02-21 2008-08-28 Capps Charles L Synergistic enhancement of calcium propionate
US8747872B2 (en) * 2007-05-02 2014-06-10 The Regents Of The University Of Michigan Nanoemulsion therapeutic compositions and methods of using the same
EP2280690A2 (de) * 2008-04-18 2011-02-09 Nanobio Corporation Verfahren zur behandlung von infektionen mit dem herpesvirus
US9144606B2 (en) 2008-04-21 2015-09-29 Nanobio Corporation Nanoemulsion influenza vaccine
WO2009132342A1 (en) * 2008-04-25 2009-10-29 Nanobio Corporation Nanoemulsions for treating fungal, yeast and mold infections
US20090269394A1 (en) * 2008-04-25 2009-10-29 Nanobio Corporation Methods and compositions for treating onchomycosis
CA2826508C (en) * 2008-05-23 2016-07-19 The Regents Of The University Of Michigan Nanoemulsion vaccines
US20090291095A1 (en) * 2008-05-23 2009-11-26 The Regents Of The University Of Michigan Nanoemulsion adjuvants
EP2349209A2 (de) * 2008-09-26 2011-08-03 Nanobio Corporation Therapeutische zusammensetzungen in nanoemulsionsform und anwendungsverfahren dafür
CN102202672A (zh) 2008-10-10 2011-09-28 达拉生物科学公司 使用穗霉素衍生物治疗或预防疼痛的方法
US20100160224A1 (en) * 2008-10-14 2010-06-24 David Thomas Shelf-stable consumable compositions containing probiotic-mimicking elements and methods of preparing and using the same
WO2010057197A1 (en) 2008-11-17 2010-05-20 The Regents Of The University Of Michigan Cancer vaccine compositions and methods of using the same
CA2750233A1 (en) 2009-01-28 2010-08-05 Nanobio Corporation Compositions for treatment and prevention of acne, methods of making the compositions, and methods of use thereof
US8668911B2 (en) 2009-05-14 2014-03-11 The Regents Of The University Of Michigan Streptococcus vaccine compositions and methods of using the same
US8617564B2 (en) 2009-05-22 2013-12-31 Genocea Biosciences, Inc. Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response
JP6110140B2 (ja) 2009-06-16 2017-04-05 ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン ナノエマルションワクチン
US20110229512A1 (en) * 2010-03-19 2011-09-22 The Regents Of The University Of Michigan Compositions and methods for diagnosing and treating urinary tract infections
EP2729169A1 (de) 2011-07-06 2014-05-14 Nanobio Corporation Impfstoff gegen humanes respiratorisches synzytialvirus
EP2747779A4 (de) 2011-08-22 2015-04-08 Nanobio Corp Herpes simplex virus impfstoff nanoemulsion
JP6460792B2 (ja) 2011-09-09 2019-01-30 ナノバイオ コーポレーション ナノエマルション呼吸器合胞体ウイルス(rsv)サブユニットワクチン
AU2012340712B2 (en) 2011-11-23 2017-09-14 Genocea Biosciences, Inc. Nucleic acid vaccines against Herpes Simplex Virus type 2: compositions and methods for eliciting an immune response
EP3204039B1 (de) 2014-10-10 2022-06-08 The Regents Of The University Of Michigan Nanoemulsionszusammensetzungen zur prävention, unterdrückung oder eliminierung von allergischen und entzündlichen erkrankungen
DK3289076T3 (da) 2015-05-01 2022-01-17 Prec Biosciences Inc Præcis sletning af kromosomale sekvenser in vivo
US11173197B2 (en) 2015-07-07 2021-11-16 Bluewillow Biologics, Inc. Methods and compositions for nanoemulsion vaccine formulations
EP3347463A1 (de) 2015-09-08 2018-07-18 Precision Biosciences, Inc. Behandlung von retinitis pigmentosa mit manipulierten meganukleasen
WO2017062439A1 (en) 2015-10-05 2017-04-13 Precision Biosciences, Inc. Engineered meganucleases with recognition sequences found in the human t cell receptor alpha constant region gene
EP3756682B8 (de) 2015-10-05 2022-04-27 Precision Biosciences, Inc. Genetisch veränderte zellen mit gen aus konstanter alpha-region modifizierter menschlicher t-zell-rezeptoren
EP3988655A3 (de) 2015-12-23 2022-08-03 Precision Biosciences, Inc. Manipulierte meganukleasen mit erkennungssequenzen im menschlichen beta-2-mikroglobulingen
WO2017189893A1 (en) 2016-04-27 2017-11-02 University Of Puerto Rico 1,5-disubstituted 1,2,3-triazoles are inhibitors of rac/cdc42 gtpases
CA3022801A1 (en) 2016-05-03 2017-11-09 Precision Biosciences, Inc. Engineered nucleases useful for treatment of hemophilia a
WO2017201390A1 (en) 2016-05-19 2017-11-23 The Regents Of The University Of Michigan Novel adjuvant compositions
EP3519427A4 (de) 2016-09-28 2020-03-11 Genocea Biosciences Inc. Verfahren und zusammensetzungen zur behandlung von herpes
ES2925644T3 (es) 2016-10-04 2022-10-19 Prec Biosciences Inc Dominios coestimuladores para su uso en células modificadas genéticamente
EP3526323B1 (de) 2016-10-14 2023-03-29 Precision Biosciences, Inc. Gentechnisch veränderte meganukleasen, die spezifisch für eine erkennungssequenz im hepatitis b virusgenom sind
WO2018073393A2 (en) 2016-10-19 2018-04-26 Cellectis Tal-effector nuclease (talen) -modified allogenic cells suitable for therapy
IL301059A (en) 2017-04-21 2023-05-01 Prec Biosciences Inc Transgenic magnonucleases specific for recognition sequences in the PCSK9 gene
EP3615662A1 (de) 2017-04-28 2020-03-04 Precision Biosciences, Inc. Verfahren zur verringerung der dna-induzierten zytotoxizität und zur verbesserung der genbearbeitung in primärzellen
EP4029943A1 (de) 2017-05-08 2022-07-20 Precision Biosciences, Inc. Nukleinsäuremoleküle, die einen manipulierten antigenrezeptor und ein hemmendes nukleinsäuremolekül codieren, und verfahren zur verwendung davon
AU2018292526A1 (en) 2017-06-30 2020-01-16 Precision Biosciences, Inc. Genetically-modified T cells comprising a modified intron in the T cell receptor alpha gene
US11547654B2 (en) * 2017-08-28 2023-01-10 University Of Louisiana At Lafayette Method of manufacture for hand-sanitizing lotion with prolonged effectiveness and resulting composition of matter
WO2019070856A1 (en) 2017-10-03 2019-04-11 Precision Biosciences, Inc. MODIFIED EPIDERMAL GROWTH FACTOR RECEPTOR PEPTIDES FOR USE IN GENETICALLY MODIFIED CELLS
EP3704238B1 (de) 2017-11-01 2024-01-03 Precision Biosciences, Inc. Gegen humane und canine faktor-viii-gene gerichtete manipulierte nukleasen als behandlung für hämophilie a
TW201945388A (zh) 2018-04-12 2019-12-01 美商精密生物科學公司 對b型肝炎病毒基因體中之識別序列具有特異性之最佳化之經工程化巨核酸酶
EP3774871B1 (de) 2018-04-12 2023-06-28 Precision BioSciences, Inc. Optimierte gentechnisch veränderte nukleasen mit spezifität für das alpha-konstantregion-gen des menschlichen t-zell-rezeptors
US11369578B2 (en) 2018-11-15 2022-06-28 Bluewillow Biologics, Inc. Persistent topical antimicrobial compositions and methods of using the same
US20210393554A1 (en) 2018-11-15 2021-12-23 Bluewillow Biologics, Inc. Nanoemulsion compositions having enhanced permeability
WO2020132659A1 (en) 2018-12-21 2020-06-25 Precision Biosciences, Inc. Genetic modification of the hydroxyacid oxidase 1 gene for treatment of primary hyperoxaluria
CN116200342A (zh) 2019-04-03 2023-06-02 精密生物科学公司 包含microRNA适应的shRNA(shRNAmiR)的遗传修饰的免疫细胞
US20220273715A1 (en) 2019-07-25 2022-09-01 Precision Biosciences, Inc. Compositions and methods for sequential stacking of nucleic acid sequences into a genomic locus
EP4017526A1 (de) 2019-08-20 2022-06-29 Precision BioSciences, Inc. Lymphdepletionsdosierungsschemata für zelluläre immuntherapien
US20220411479A1 (en) 2019-10-30 2022-12-29 Precision Biosciences, Inc. Cd20 chimeric antigen receptors and methods of use for immunotherapy
EP4069729A1 (de) 2019-12-06 2022-10-12 Precision BioSciences, Inc. Optimierte, manipulierte meganukleasen mit spezifität für eine erkennungssequenz im hepatitis-b-virus-genom
EP4069285A1 (de) 2019-12-06 2022-10-12 Precision BioSciences, Inc. Methoden zur krebsimmuntherapie unter verwendung von lymphodepletionsregimen und allogenen cd19-, cd20- oder bcma-car-t-zellen
US20230183664A1 (en) 2020-05-11 2023-06-15 Precision Biosciences, Inc. Self-limiting viral vectors encoding nucleases
CA3172171A1 (en) 2020-05-12 2021-11-18 Victor Bartsevich Treatment of retinitis pigmentosa using improved engineered meganucleases
WO2022035793A1 (en) 2020-08-10 2022-02-17 Precision Biosciences, Inc. Antibodies and fragments specific for b-cell maturation antigen and uses thereof
WO2022035309A1 (en) * 2020-08-14 2022-02-17 Universiti Putra Malaysia Nano emulsion composition having antimicrobial properties
WO2022040582A1 (en) 2020-08-21 2022-02-24 Precision Biosciences, Inc. Engineered meganucleases having specificity for a recognition sequence in the transthyretin gene
JP2023549357A (ja) 2020-11-12 2023-11-24 プレシジョン バイオサイエンシズ,インク. ジストロフィン遺伝子内の認識配列に特異性を有する遺伝子操作されたメガヌクレアーゼ
CA3172161A1 (en) 2021-01-08 2022-07-14 James Jefferson Smith Engineered meganucleases having specificity for a recognition sequence in the hydroxyacid oxidase 1 gene
EP4284823A1 (de) 2021-01-28 2023-12-06 Precision BioSciences, Inc. Modulation der tgf-beta-signalisierung in genetisch modifizierten eukaryotischen zellen
EP4326861A1 (de) 2021-04-22 2024-02-28 Precision Biosciences, Inc. Manipulierte meganukleasen gegen menschliche mitochondriale genome
AU2022262778A1 (en) 2021-04-22 2023-11-30 Precision Biosciences, Inc. Engineered meganucleases that target human mitochondrial genomes
IL312243A (en) 2021-10-19 2024-06-01 Prec Biosciences Inc Gene editing methods to treat alpha-1 antitrypsin (AAT) deficiency
WO2023070003A1 (en) 2021-10-19 2023-04-27 Precision Biosciences, Inc. Gene editing methods for treating alpha-1 antitrypsin (aat) deficiency
WO2023081767A1 (en) 2021-11-05 2023-05-11 Precision Biosciences, Inc. Methods for immunotherapy

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020183A (en) * 1974-12-03 1977-04-26 Ortho Pharmaceutical Corporation Nonionic surface active anti-herpes simplex viral agents
US4412985A (en) * 1980-10-06 1983-11-01 Edward Shanbrom Depyrogenation process
US4540573A (en) * 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4909940A (en) * 1987-12-30 1990-03-20 New York Blood Center, Inc. Extraction of process chemicals from labile biological mixtures with organic alcohols or with halogenated hydrocarbons
EP0382814B1 (de) * 1988-06-22 1994-02-16 Applied Microbiology, Inc. Nisin-zusammensetzungen zur anwendung als erhöhte breit-spektrum-bakterizide
US5156973A (en) * 1988-11-23 1992-10-20 Edward Shanbrom Antiviral blood sampling process and apparatus
JP3628343B2 (ja) * 1993-11-01 2005-03-09 亘起物産有限会社 ウィルス不活化剤
JPH07196408A (ja) * 1993-12-28 1995-08-01 Amano Pharmaceut Co Ltd 抗菌性組成物
US5547677A (en) * 1994-05-20 1996-08-20 Novavax, Inc. Antimicrobial oil-in-water emulsions
JPH10500686A (ja) * 1994-05-20 1998-01-20 ノババックス インコーポレイテッド 抗菌性水中油エマルジョン
US5549901A (en) * 1994-05-20 1996-08-27 Novavax, Inc. Antimicrobial oil-in-water emulsions
US6034073A (en) * 1995-04-24 2000-03-07 Novavax, Inc. Solvent detergent emulsions having antiviral activity
JP2868206B2 (ja) * 1996-04-16 1999-03-10 株式会社オフテクス 消毒および/または防腐のための有害微生物防除用組成物

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ATE356549T1 (de) 2007-04-15
EP1041978A1 (de) 2000-10-11
EP1041978A4 (de) 2004-05-19
HK1031839A1 (en) 2001-06-29
WO1999033459A1 (en) 1999-07-08
US6015832A (en) 2000-01-18
JP2001527041A (ja) 2001-12-25
DE69837348T2 (de) 2007-11-29
IL137093A (en) 2007-03-08
IL137093A0 (en) 2001-06-14
AU2019899A (en) 1999-07-19
EP1041978B1 (de) 2007-03-14
CA2316888C (en) 2007-06-19
CA2316888A1 (en) 1999-07-08
AU749817B2 (en) 2002-07-04
JP4683724B2 (ja) 2011-05-18

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