DE69837221D1 - Methode zur bewertung von verbindungen in bezug auf ihres effektes auf die haut - Google Patents

Methode zur bewertung von verbindungen in bezug auf ihres effektes auf die haut

Info

Publication number
DE69837221D1
DE69837221D1 DE69837221T DE69837221T DE69837221D1 DE 69837221 D1 DE69837221 D1 DE 69837221D1 DE 69837221 T DE69837221 T DE 69837221T DE 69837221 T DE69837221 T DE 69837221T DE 69837221 D1 DE69837221 D1 DE 69837221D1
Authority
DE
Germany
Prior art keywords
skin
effect
compounds related
evaluating compounds
evaluating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69837221T
Other languages
English (en)
Other versions
DE69837221T2 (de
Inventor
Robert E Burgeson
Satoshi Amano
Jiro Kishimoto
Toshio Nishiyama
Ritsuko Ehama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shiseido Co Ltd
General Hospital Corp
Original Assignee
Shiseido Co Ltd
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shiseido Co Ltd, General Hospital Corp filed Critical Shiseido Co Ltd
Publication of DE69837221D1 publication Critical patent/DE69837221D1/de
Application granted granted Critical
Publication of DE69837221T2 publication Critical patent/DE69837221T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0006—Skin tests, e.g. intradermal testing, test strips, delayed hypersensitivity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0393—Animal model comprising a reporter system for screening tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69837221T 1997-12-17 1998-04-30 Methode zur bewertung von verbindungen in bezug auf ihres effektes auf die haut Expired - Lifetime DE69837221T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6994597P 1997-12-17 1997-12-17
US69945P 1997-12-17
PCT/US1998/008794 WO1999030743A1 (en) 1997-12-17 1998-04-30 Methods for evaluating a compound for its effect on skin

Publications (2)

Publication Number Publication Date
DE69837221D1 true DE69837221D1 (de) 2007-04-12
DE69837221T2 DE69837221T2 (de) 2007-12-20

Family

ID=22092172

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69837221T Expired - Lifetime DE69837221T2 (de) 1997-12-17 1998-04-30 Methode zur bewertung von verbindungen in bezug auf ihres effektes auf die haut

Country Status (5)

Country Link
EP (1) EP1067968B1 (de)
JP (1) JP4125486B2 (de)
AU (1) AU7172498A (de)
DE (1) DE69837221T2 (de)
WO (1) WO1999030743A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7163679B1 (en) 1999-05-06 2007-01-16 The General Hospital Corporation Versican and epithelial-mesenchymal interaction
EP1181352A4 (de) * 1999-05-06 2002-08-07 Gen Hospital Corp Versican und epithel-mesenchym wechselwirkung
WO2001017343A1 (en) * 1999-09-10 2001-03-15 The General Hospital Corporation Methods for evaluating a compound for its effect on skin
WO2002061116A1 (en) 2001-01-31 2002-08-08 The General Hospital Corporation In vivo screening array
GB201700138D0 (en) 2017-01-05 2017-02-22 Senzagen Ab Analytical methods and arrays for use in the same
JP7316745B2 (ja) 2016-05-20 2023-07-28 株式会社リコー 三次元組織体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2152753B1 (es) * 1993-03-29 2001-09-01 Ct Investig Energeticas Ciemat Animales transgenicos para la determinacion de agentes que estimulan o reprimen la hiperproliferacion epidermica y el crecimiento del pelo
EP0831931A4 (de) * 1995-05-24 2001-09-26 Bernstein Eric F Ein in vivo und in vitro modell für die lichtalterung der haut

Also Published As

Publication number Publication date
EP1067968B1 (de) 2007-02-28
JP4125486B2 (ja) 2008-07-30
AU7172498A (en) 1999-07-05
EP1067968A4 (de) 2001-06-13
JP2002508339A (ja) 2002-03-19
WO1999030743A1 (en) 1999-06-24
DE69837221T2 (de) 2007-12-20
EP1067968A1 (de) 2001-01-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition