DE69827998D1 - kurze PNA Oligonukleotide in Triplexkomplexen - Google Patents

kurze PNA Oligonukleotide in Triplexkomplexen

Info

Publication number
DE69827998D1
DE69827998D1 DE1998627998 DE69827998T DE69827998D1 DE 69827998 D1 DE69827998 D1 DE 69827998D1 DE 1998627998 DE1998627998 DE 1998627998 DE 69827998 T DE69827998 T DE 69827998T DE 69827998 D1 DE69827998 D1 DE 69827998D1
Authority
DE
Germany
Prior art keywords
pna oligonucleotides
short pna
triplex complexes
triplex
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1998627998
Other languages
English (en)
Other versions
DE69827998T2 (de
Inventor
Michael Naesby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PNA Diagnostics ApS Denmark
Original Assignee
PNA Diagnostics ApS Denmark
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PNA Diagnostics ApS Denmark filed Critical PNA Diagnostics ApS Denmark
Application granted granted Critical
Publication of DE69827998D1 publication Critical patent/DE69827998D1/de
Publication of DE69827998T2 publication Critical patent/DE69827998T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
DE69827998T 1997-08-22 1998-08-19 kurze PNA Oligonukleotide in Triplexkomplexen Expired - Lifetime DE69827998T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97114512 1997-08-22
EP97114512 1997-08-22

Publications (2)

Publication Number Publication Date
DE69827998D1 true DE69827998D1 (de) 2005-01-13
DE69827998T2 DE69827998T2 (de) 2005-10-06

Family

ID=8227256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69827998T Expired - Lifetime DE69827998T2 (de) 1997-08-22 1998-08-19 kurze PNA Oligonukleotide in Triplexkomplexen

Country Status (5)

Country Link
US (1) US6979536B1 (de)
EP (1) EP0897991B1 (de)
JP (1) JP4235283B2 (de)
DE (1) DE69827998T2 (de)
DK (1) DK0897991T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1412517T3 (da) 2001-03-09 2007-03-05 Boston Probes Inc Fremgangsmåder, kits og sammensætninger af kombinationsoligomerer
US7782569B2 (en) 2007-01-18 2010-08-24 Sae Magnetics (Hk) Ltd. Magnetic recording head and media comprising aluminum oxynitride underlayer and a diamond-like carbon overcoat
US8014104B2 (en) * 2007-03-21 2011-09-06 Sae Magnetics (Hk) Ltd. Magnetic head/disk with transition metal oxynitride adhesion/corrosion barrier and diamond-like carbon overcoat bilayer
DK3350343T3 (da) 2015-09-16 2020-07-20 Petaomics Inc Fremgangsmåder og sammensætninger til genommålberigelse og selektiv dna-sekventering

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834185A (en) * 1986-10-28 1998-11-10 Johns Hopkins University Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs, triple helix complexes formed thereby and oligomers used in their formation
US5422251A (en) * 1986-11-26 1995-06-06 Princeton University Triple-stranded nucleic acids
US5176996A (en) * 1988-12-20 1993-01-05 Baylor College Of Medicine Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
WO1992011390A1 (en) * 1990-12-17 1992-07-09 Idexx Laboratories, Inc. Nucleic acid sequence detection by triple helix formation
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US6403302B1 (en) * 1992-09-17 2002-06-11 California Institute Of Technology Methods and compositions for triple helix formation
US6020126A (en) * 1996-03-21 2000-02-01 Hsc, Reasearch And Development Limited Partnership Rapid genetic screening method
US5906976A (en) * 1996-10-22 1999-05-25 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Method and composition for treating neuronal degeneration
CA2218439A1 (en) * 1996-12-21 1998-06-21 Henrik Orum Method of identifying a nucleic acid using triple helix formation of adjacently annealed probes

Also Published As

Publication number Publication date
DK0897991T3 (da) 2005-07-25
JPH11127876A (ja) 1999-05-18
DE69827998T2 (de) 2005-10-06
US6979536B1 (en) 2005-12-27
JP4235283B2 (ja) 2009-03-11
EP0897991A2 (de) 1999-02-24
EP0897991A3 (de) 2002-07-24
EP0897991B1 (de) 2004-12-08

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Legal Events

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