DE69821242D1 - Optisches assay-verfahren mit nahezu senkrechtem lichteinfall und wellenlängen- und winkelempfindlichkeit - Google Patents

Optisches assay-verfahren mit nahezu senkrechtem lichteinfall und wellenlängen- und winkelempfindlichkeit

Info

Publication number
DE69821242D1
DE69821242D1 DE69821242T DE69821242T DE69821242D1 DE 69821242 D1 DE69821242 D1 DE 69821242D1 DE 69821242 T DE69821242 T DE 69821242T DE 69821242 T DE69821242 T DE 69821242T DE 69821242 D1 DE69821242 D1 DE 69821242D1
Authority
DE
Germany
Prior art keywords
wavelength
assay procedure
vertical incidence
near vertical
optical assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69821242T
Other languages
English (en)
Other versions
DE69821242T2 (de
Inventor
A Challener
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlassBridge Enterprises Inc
Original Assignee
Imation Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imation Corp filed Critical Imation Corp
Application granted granted Critical
Publication of DE69821242D1 publication Critical patent/DE69821242D1/de
Publication of DE69821242T2 publication Critical patent/DE69821242T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • G01N21/553Attenuated total reflection and using surface plasmons
    • G01N21/554Attenuated total reflection and using surface plasmons detecting the surface plasmon resonance of nanostructured metals, e.g. localised surface plasmon resonance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/806Electrical property or magnetic property
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE69821242T 1997-08-20 1998-08-18 Optisches assay-verfahren mit nahezu senkrechtem lichteinfall und wellenlängen- und winkelempfindlichkeit Expired - Fee Related DE69821242T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/915,057 US5955378A (en) 1997-08-20 1997-08-20 Near normal incidence optical assaying method and system having wavelength and angle sensitivity
PCT/US1998/017084 WO1999009392A2 (en) 1997-08-20 1998-08-18 Near normal incidence optical assaying method and system having wavelength and angle sensitivity
US915057 2001-07-25

Publications (2)

Publication Number Publication Date
DE69821242D1 true DE69821242D1 (de) 2004-02-26
DE69821242T2 DE69821242T2 (de) 2004-11-04

Family

ID=25435145

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69821242T Expired - Fee Related DE69821242T2 (de) 1997-08-20 1998-08-18 Optisches assay-verfahren mit nahezu senkrechtem lichteinfall und wellenlängen- und winkelempfindlichkeit

Country Status (5)

Country Link
US (2) US5955378A (de)
EP (1) EP1005634B1 (de)
JP (1) JP2001516017A (de)
DE (1) DE69821242T2 (de)
WO (1) WO1999009392A2 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994150A (en) 1997-11-19 1999-11-30 Imation Corp. Optical assaying method and system having rotatable sensor disk with multiple sensing regions
US6235534B1 (en) * 1998-04-27 2001-05-22 Ronald Frederich Brookes Incremental absorbance scanning of liquid in dispensing tips
US6320991B1 (en) 1998-10-16 2001-11-20 Imation Corp. Optical sensor having dielectric film stack
US8111401B2 (en) 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US6466323B1 (en) 1999-11-23 2002-10-15 Westinghouse Savannah River Company, L.L.C. Surface plasmon resonance spectroscopy sensor and methods for using same
US7118710B2 (en) * 2000-10-30 2006-10-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US20030113766A1 (en) * 2000-10-30 2003-06-19 Sru Biosystems, Llc Amine activated colorimetric resonant biosensor
US7217574B2 (en) * 2000-10-30 2007-05-15 Sru Biosystems, Inc. Method and apparatus for biosensor spectral shift detection
US7306827B2 (en) * 2000-10-30 2007-12-11 Sru Biosystems, Inc. Method and machine for replicating holographic gratings on a substrate
US7875434B2 (en) 2000-10-30 2011-01-25 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US7202076B2 (en) 2000-10-30 2007-04-10 Sru Biosystems, Inc. Label-free high-throughput optical technique for detecting biomolecular interactions
US7175980B2 (en) * 2000-10-30 2007-02-13 Sru Biosystems, Inc. Method of making a plastic colorimetric resonant biosensor device with liquid handling capabilities
US7575939B2 (en) * 2000-10-30 2009-08-18 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7615339B2 (en) 2000-10-30 2009-11-10 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7101660B2 (en) 2000-10-30 2006-09-05 Sru Biosystems, Inc. Method for producing a colorimetric resonant reflection biosensor on rigid surfaces
US7371562B2 (en) 2000-10-30 2008-05-13 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7264973B2 (en) * 2000-10-30 2007-09-04 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant optical biosensor
US7023544B2 (en) * 2000-10-30 2006-04-04 Sru Biosystems, Inc. Method and instrument for detecting biomolecular interactions
US7142296B2 (en) 2000-10-30 2006-11-28 Sru Biosystems, Inc. Method and apparatus for detecting biomolecular interactions
US6951715B2 (en) * 2000-10-30 2005-10-04 Sru Biosystems, Inc. Optical detection of label-free biomolecular interactions using microreplicated plastic sensor elements
US7153702B2 (en) 2000-10-30 2006-12-26 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US20030092075A1 (en) * 2000-10-30 2003-05-15 Sru Biosystems, Llc Aldehyde chemical surface activation processes and test methods for colorimetric resonant sensors
US7070987B2 (en) 2000-10-30 2006-07-04 Sru Biosystems, Inc. Guided mode resonant filter biosensor using a linear grating surface structure
US7300803B2 (en) * 2000-10-30 2007-11-27 Sru Biosystems, Inc. Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
US6576430B1 (en) * 2000-11-20 2003-06-10 Becton, Dickinson And Company Detection of ligands by refractive surface methods
US20020135771A1 (en) * 2001-01-19 2002-09-26 Quantech Ltd System and method of reducing particulate interference in fluid analyte detection
JP3793430B2 (ja) * 2001-07-18 2006-07-05 株式会社日立製作所 近接場光を用いた光学装置
TW593999B (en) * 2001-12-21 2004-06-21 Univ Nat Taiwan Surface plasma seed resonance sensing system and method
US7927822B2 (en) 2002-09-09 2011-04-19 Sru Biosystems, Inc. Methods for screening cells and antibodies
US7429492B2 (en) 2002-09-09 2008-09-30 Sru Biosystems, Inc. Multiwell plates with integrated biosensors and membranes
US7309614B1 (en) 2002-12-04 2007-12-18 Sru Biosystems, Inc. Self-referencing biodetection method and patterned bioassays
CA2423512A1 (en) * 2003-03-26 2004-09-26 Institut National D'optique Optical sensor for volatile organic compounds
US7497992B2 (en) * 2003-05-08 2009-03-03 Sru Biosystems, Inc. Detection of biochemical interactions on a biosensor using tunable filters and tunable lasers
US7057720B2 (en) 2003-06-24 2006-06-06 Corning Incorporated Optical interrogation system and method for using same
US7292333B2 (en) * 2003-06-24 2007-11-06 Corning Incorporated Optical interrogation system and method for 2-D sensor arrays
GB0318808D0 (en) * 2003-08-11 2003-09-10 Toshiba Res Europ Ltd An encoded carrier
US8298780B2 (en) 2003-09-22 2012-10-30 X-Body, Inc. Methods of detection of changes in cells
EP1680679A2 (de) * 2003-11-06 2006-07-19 SRU Biosystems Inc. Mit aminen in hoher dichte funktionalisierte oberfläche
JP2005189198A (ja) * 2003-12-26 2005-07-14 Fuji Photo Film Co Ltd 光学デバイス
SE0500484L (sv) 2004-10-28 2006-04-29 All Set Marine Lashing Ab Lastsäkringsanordning
EP1904858A1 (de) 2005-07-20 2008-04-02 Corning Incorporated Markierungsfreies biomolekulares screening-system und -verfahren mit hohem durchsatz
US7483127B1 (en) 2005-08-08 2009-01-27 Sru Biosystems, Inc. Method and apparatus for generating an image of biomolecular sensor target area
EP2208985A1 (de) * 2005-08-11 2010-07-21 SRU Biosystems Inc. Markerfreie Bindungsdetektion und Fluoreszenz-Verstärkung kombinierende Analysemethode
US7790406B2 (en) * 2005-08-11 2010-09-07 Sru Biosystems, Inc Grating-based sensor combining label-free binding detection and fluorescence amplification and readout system for sensor
US20070279634A1 (en) * 2006-05-31 2007-12-06 Gruhlke Russell W Label-free grating-based surface plasmon resonance sensor
EP2041583A1 (de) * 2006-06-30 2009-04-01 Corning Incorporated Flüssigkeitshandhabungssystem für durchflusstest
US7976217B2 (en) 2006-09-15 2011-07-12 Corning Incorporated Screening system and method for analyzing a plurality of biosensors
US7737392B2 (en) * 2006-11-09 2010-06-15 The Board Of Trustees Of The University Of Illinois Photonic crystal sensors with integrated fluid containment structure, sample handling devices incorporating same, and uses thereof for biomolecular interaction analysis
PT103601B (pt) * 2006-11-09 2008-10-14 Biosurfit Sa Dispositivo de detecção baseado no efeito de ressonância de plasmão de superfície
AU2008242664B2 (en) * 2007-04-19 2011-10-20 Sru Biosystems, Inc. Method for employing a biosensor to detect small molecules that bind directly to immobilized targets
CN100582745C (zh) * 2007-05-23 2010-01-20 中国科学院光电技术研究所 单面刻槽表面等离子体生化传感器
KR100865755B1 (ko) * 2007-06-29 2008-10-28 삼성전기주식회사 표면 플라즈몬 공명을 이용한 다채널 바이오 센서
US9134307B2 (en) 2007-07-11 2015-09-15 X-Body, Inc. Method for determining ion channel modulating properties of a test reagent
JP2010532998A (ja) 2007-07-11 2010-10-21 エス アール ユー バイオシステムズ,インコーポレイテッド イオンチャネルのモジュレータを識別する方法
EP2060904A1 (de) * 2007-11-13 2009-05-20 Koninklijke Philips Electronics N.V. Biosensor zur Plasmonenrasterung
WO2009091902A1 (en) * 2008-01-17 2009-07-23 The Salk Institute For Biological Studies 3d scanning acousto-optic microscope
US8257936B2 (en) 2008-04-09 2012-09-04 X-Body Inc. High resolution label free analysis of cellular properties
US8094316B1 (en) * 2008-05-12 2012-01-10 Institute Of Photonics And Electronics As Cr, V.V.I. Surface plasmon resonance coupler and disperser sensor
EP2304500A1 (de) * 2008-06-04 2011-04-06 SRU Biosystems, Inc. Detektion von promiskuitiven kleinen submikrometeraggregaten
GB2464721C (en) 2008-10-23 2013-08-14 Biosurfit Sa Jet deflection device
GB2466644B (en) 2008-12-30 2011-05-11 Biosurfit Sa Liquid handling
WO2011059999A1 (en) * 2009-11-16 2011-05-19 Corning Incorporated Non-spectroscopic label-independent optical reader system and methods
GB2476474B (en) 2009-12-22 2012-03-28 Biosurfit Sa Surface plasmon resonance detection system
GB2479139A (en) 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
JP6257521B2 (ja) 2011-12-08 2018-01-10 バイオサーフィット、 ソシエダッド アノニマ 逐次分注および沈降速度の指標の決定
GB201216645D0 (en) * 2012-09-18 2012-10-31 Univ Nottingham Surface plasmon microscopy
US10481089B2 (en) * 2013-03-12 2019-11-19 Integrated Plasmonics Corporation Optical detection system with tilted sensor

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0112721B1 (de) * 1982-12-21 1988-05-18 Ares-Serono N.V. Testverfahren
GB8423204D0 (en) * 1984-09-14 1984-10-17 Comtech Res Unit Assay technique and equipment
US5118605A (en) * 1984-10-16 1992-06-02 Chiron Corporation Polynucleotide determination with selectable cleavage sites
GB8509492D0 (en) * 1985-04-12 1985-05-15 Plessey Co Plc Optical assay
AU5815886A (en) * 1985-05-29 1986-12-24 Kurt Tiefenthaler Optical sensor for selectively determining the presence of substances and the variation of the refraction index in the measured substances
GB8618133D0 (en) * 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
GB8618159D0 (en) * 1986-07-25 1986-09-03 Pa Consulting Services Spectrometer based instruments
GB8705649D0 (en) * 1987-03-10 1987-04-15 Pa Consulting Services Assay sensor
GB8714503D0 (en) * 1987-06-20 1987-07-22 Pa Consulting Services Detector
CA1321488C (en) * 1987-08-22 1993-08-24 Martin Francis Finlan Biological sensors
EP0341928A1 (de) * 1988-05-10 1989-11-15 AMERSHAM INTERNATIONAL plc Oberflächen-Resonanzplasmawellen-Sensoren
US5478755A (en) * 1988-07-25 1995-12-26 Ares Serono Research & Development Ltd. Long range surface plasma resonance immunoassay
SE8804074D0 (sv) * 1988-11-10 1988-11-10 Pharmacia Ab Sensorenhet och dess anvaendning i biosensorsystem
GB8916764D0 (en) * 1989-07-21 1989-09-06 Sambles John R Surface plasmon optical sensor
FI85768C (fi) * 1990-07-04 1992-05-25 Valtion Teknillinen Foerfarande foer utfoerning av ytplasmonresonansmaetning samt i foerfarandet anvaendbar givare.
US5583643A (en) * 1991-04-12 1996-12-10 British Technology Group Ltd. Methods of and apparatus for measurement using acousto-optic devices
GB2256477B (en) * 1991-06-07 1995-03-08 Marconi Gec Ltd An optical sensor
EP0517930B1 (de) * 1991-06-08 1995-05-24 Hewlett-Packard GmbH Verfahren und Gerät zur Feststellung und/oder Konzentrationsbestimmung von Biomolekülen
GB9120000D0 (en) * 1991-09-19 1991-11-06 British Gas Plc Optical sensing
GB9200564D0 (en) * 1992-01-11 1992-03-11 Fisons Plc Analytical device with variable angle of incidence
US5351127A (en) * 1992-06-17 1994-09-27 Hewlett-Packard Company Surface plasmon resonance measuring instruments
GB9314991D0 (en) * 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
US5636633A (en) * 1995-08-09 1997-06-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
US5751482A (en) * 1996-04-22 1998-05-12 Imation Corp. Achromatic polarization-rotating right-angle prism system
EP1650547B1 (de) * 1996-04-30 2011-10-19 FUJIFILM Corporation Oberflächenplasmonensensor
US5776785A (en) * 1996-12-30 1998-07-07 Diagnostic Products Corporation Method and apparatus for immunoassay using fluorescent induced surface plasma emission

Also Published As

Publication number Publication date
US6100991A (en) 2000-08-08
DE69821242T2 (de) 2004-11-04
WO1999009392A3 (en) 1999-06-03
EP1005634B1 (de) 2004-01-21
US5955378A (en) 1999-09-21
JP2001516017A (ja) 2001-09-25
EP1005634A2 (de) 2000-06-07
WO1999009392A2 (en) 1999-02-25

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