DE69806902T2 - Neue 1,4-dihydropyridinderivate und deren therapeutische anwendung - Google Patents

Neue 1,4-dihydropyridinderivate und deren therapeutische anwendung

Info

Publication number
DE69806902T2
DE69806902T2 DE69806902T DE69806902T DE69806902T2 DE 69806902 T2 DE69806902 T2 DE 69806902T2 DE 69806902 T DE69806902 T DE 69806902T DE 69806902 T DE69806902 T DE 69806902T DE 69806902 T2 DE69806902 T2 DE 69806902T2
Authority
DE
Germany
Prior art keywords
new
pct
therapeutic applications
dihydropyridine derivatives
date jul
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69806902T
Other languages
English (en)
Other versions
DE69806902D1 (de
Inventor
Gerard Duret
Gerard Glauert
Marguerite Henry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cephalon France SAS
Original Assignee
Laboratoire L Lafon SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire L Lafon SA filed Critical Laboratoire L Lafon SA
Application granted granted Critical
Publication of DE69806902D1 publication Critical patent/DE69806902D1/de
Publication of DE69806902T2 publication Critical patent/DE69806902T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/42Oxygen atoms attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
DE69806902T 1997-01-21 1998-01-12 Neue 1,4-dihydropyridinderivate und deren therapeutische anwendung Expired - Lifetime DE69806902T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9700577A FR2758558B1 (fr) 1997-01-21 1997-01-21 Nouveaux derives de la 1,4-dihydropyridine et leur utilisation en therapeutique
PCT/FR1998/000042 WO1998031680A1 (fr) 1997-01-21 1998-01-12 Derives de la 1,4-dihydropyridine et leur utilisation en therapeutique

Publications (2)

Publication Number Publication Date
DE69806902D1 DE69806902D1 (de) 2002-09-05
DE69806902T2 true DE69806902T2 (de) 2002-12-12

Family

ID=9502803

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69806902T Expired - Lifetime DE69806902T2 (de) 1997-01-21 1998-01-12 Neue 1,4-dihydropyridinderivate und deren therapeutische anwendung

Country Status (14)

Country Link
US (1) US6166035A (de)
EP (1) EP0958290B1 (de)
JP (1) JP4163260B2 (de)
AT (1) ATE221528T1 (de)
AU (1) AU727876B2 (de)
CA (1) CA2278223C (de)
DE (1) DE69806902T2 (de)
DK (1) DK0958290T3 (de)
ES (1) ES2181160T3 (de)
FR (1) FR2758558B1 (de)
NO (1) NO315853B1 (de)
NZ (1) NZ336585A (de)
PT (1) PT958290E (de)
WO (1) WO1998031680A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391881B2 (en) * 2000-05-19 2002-05-21 Bristol-Myers Squibb Company Thiourea derivatives of dihydropyridine NPY antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2671349B1 (fr) * 1991-01-09 1993-04-23 Lafon Labor Nouveaux derives de 1,4-dihydropyridine, leur procede de preparation et composition therapeutique les contenant.

Also Published As

Publication number Publication date
PT958290E (pt) 2002-11-29
JP2001508788A (ja) 2001-07-03
ATE221528T1 (de) 2002-08-15
US6166035A (en) 2000-12-26
AU5870298A (en) 1998-08-07
FR2758558A1 (fr) 1998-07-24
ES2181160T3 (es) 2003-02-16
CA2278223A1 (fr) 1998-07-23
FR2758558B1 (fr) 1999-04-16
NZ336585A (en) 2000-09-29
NO993546L (no) 1999-09-21
EP0958290B1 (de) 2002-07-31
WO1998031680A1 (fr) 1998-07-23
NO993546D0 (no) 1999-07-19
JP4163260B2 (ja) 2008-10-08
AU727876B2 (en) 2001-01-04
DE69806902D1 (de) 2002-09-05
DK0958290T3 (da) 2002-12-02
CA2278223C (fr) 2008-07-22
EP0958290A1 (de) 1999-11-24
NO315853B1 (no) 2003-11-03

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