DE69804918D1 - Sehr niedrigdosiertes orales Kontrazeptiv mit weniger Menstruationsblutungen und verzögerter Wirkung - Google Patents
Sehr niedrigdosiertes orales Kontrazeptiv mit weniger Menstruationsblutungen und verzögerter WirkungInfo
- Publication number
- DE69804918D1 DE69804918D1 DE69804918T DE69804918T DE69804918D1 DE 69804918 D1 DE69804918 D1 DE 69804918D1 DE 69804918 T DE69804918 T DE 69804918T DE 69804918 T DE69804918 T DE 69804918T DE 69804918 D1 DE69804918 D1 DE 69804918D1
- Authority
- DE
- Germany
- Prior art keywords
- menstrual bleeding
- less
- low
- oral contraceptive
- dose oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- 230000000740 bleeding effect Effects 0.000 title abstract 2
- 230000002175 menstrual effect Effects 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 229940127234 oral contraceptive Drugs 0.000 title 1
- 239000003539 oral contraceptive agent Substances 0.000 title 1
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
- 239000000262 estrogen Substances 0.000 abstract 2
- 229940011871 estrogen Drugs 0.000 abstract 2
- 239000000583 progesterone congener Substances 0.000 abstract 2
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 abstract 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 abstract 1
- IMONTRJLAWHYGT-ZCPXKWAGSA-N Norethindrone Acetate Chemical compound C1CC2=CC(=O)CC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CC[C@](C#C)(OC(=O)C)[C@@]1(C)CC2 IMONTRJLAWHYGT-ZCPXKWAGSA-N 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960002568 ethinylestradiol Drugs 0.000 abstract 1
- 229960001652 norethindrone acetate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Confectionery (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/880,419 US5898032A (en) | 1997-06-23 | 1997-06-23 | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
CA002256977A CA2256977C (en) | 1997-06-23 | 1998-12-23 | Methods of extended use oral contraception |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69804918D1 true DE69804918D1 (de) | 2002-05-23 |
DE69804918T2 DE69804918T2 (de) | 2002-11-07 |
Family
ID=32043766
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69804918T Revoked DE69804918T2 (de) | 1997-06-23 | 1998-06-15 | Sehr niedrigdosiertes orales Kontrazeptiv mit weniger Menstruationsblutungen und verzögerter Wirkung |
Country Status (10)
Country | Link |
---|---|
US (2) | US5898032A (de) |
EP (1) | EP0911029B1 (de) |
JP (1) | JPH1129481A (de) |
AT (1) | ATE216241T1 (de) |
CA (1) | CA2256977C (de) |
DE (1) | DE69804918T2 (de) |
DK (1) | DK0911029T3 (de) |
ES (1) | ES2175650T3 (de) |
NO (1) | NO982815L (de) |
PT (1) | PT911029E (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19549264A1 (de) * | 1995-12-23 | 1997-06-26 | Schering Ag | Verfahren und Kit zur Kontrazeption |
WO2001030355A1 (fr) | 1999-10-25 | 2001-05-03 | Laboratoire Theramex | Medicament contraceptif a base d'un progestatif et d'un estrogene et son mode de preparation |
FR2754179B1 (fr) | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
US5898032A (en) | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
US6251956B1 (en) | 1998-08-20 | 2001-06-26 | Ortho Pharmaceutical Corporation | Combination progestin oral contraceptive regimen |
DE19739916C2 (de) | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
WO2000028995A1 (en) * | 1998-11-12 | 2000-05-25 | Warner Chilcott Laboratories Ireland Limited | Graduated progestin contraceptive |
US7297688B2 (en) | 2000-06-08 | 2007-11-20 | Wyeth | Starter kit for low dose oral contraceptives |
DE10045380A1 (de) * | 2000-09-14 | 2002-04-04 | Schering Ag | Verfahren zur Kontrazeption und dessen Darreichungsform |
ATE526973T1 (de) * | 2001-06-18 | 2011-10-15 | Noven Pharma | Verbesserte arzneimittelabgabe in transdermalen systemen |
US20030018018A1 (en) * | 2001-07-10 | 2003-01-23 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with sustained efficacy and induced amenorrhea |
SI1453521T1 (sl) * | 2001-12-05 | 2013-11-29 | Teva Women's Health, Inc. | Oralni kontraceptiki za preprečevanje nosečnosti in zmanjševanje predmenstrualne simptomatike |
JP2006525358A (ja) * | 2003-05-02 | 2006-11-09 | ドゥラメド ファーマシューティカルズ, インコーポレイテッド | 長期周期避妊養生法を利用するホルモン治療の方法 |
RU2403046C2 (ru) * | 2003-07-16 | 2010-11-10 | Тева Вимен'С Хелс, Инк. | Способы гормонального лечения с применением контрацептивных режимов с непрерывным введением эстрогена |
NZ546185A (en) * | 2003-09-04 | 2008-12-24 | Pharmadesign Inc | Case with pill receiving sleeves for storing and dispensing pills |
WO2005032558A1 (en) * | 2003-10-01 | 2005-04-14 | Janssen Pharmaceutica N.V. | Extended triphasic contraceptive regimens |
EP1535618A1 (de) * | 2003-11-26 | 2005-06-01 | Schering Aktiengesellschaft | Pharmazeutische Zubereitung zur kontinuierlichen hormonellen Behandlung über einen Zeitraum von über 21-28 Tage beinhaltend zwei Estrogen und/oder Progestin Zusammensetzungen |
ES2397983T3 (es) | 2004-03-19 | 2013-03-12 | Warner Chilcott Company, Llc | Procedimiento anticonceptivo oral multifásico de ciclo prolongado |
DE102004019743B4 (de) | 2004-04-20 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | Mehrphasenpräparat zur Kontrazeption auf der Basis eines natürlichen Estrogens |
MY151322A (en) | 2004-04-30 | 2014-05-15 | Bayer Ip Gmbh | Management of breakthrough bleeding in extended hormonal contraceptive regimens |
DE102004026671A1 (de) * | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Darreichungsform zur hormonalen Kontrazeption |
DE102004026670A1 (de) | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat |
DE102004026679A1 (de) | 2004-05-28 | 2005-12-15 | Grünenthal GmbH | Hormonales Kontrazeptivum enthaltend eine Kombination aus Ethinylestradiol und Chlormadinonacetat |
US8501720B2 (en) * | 2004-07-30 | 2013-08-06 | Bayer Pharma AG | Method for treatment of dysmenorrhea |
MX2007004120A (es) * | 2004-10-07 | 2007-06-15 | Duramed Pharmaceuticals Inc | Metodos de tratamiento hormonal utilizando regimentes de ciclo prolongado de dosis ascendente. |
US20070111975A1 (en) | 2004-10-07 | 2007-05-17 | Duramed Pharmaceuticals, Inc. | Methods of Hormonal Treatment Utilizing Ascending-Dose Extended Cycle Regimens |
US20060079491A1 (en) * | 2004-10-08 | 2006-04-13 | Andreas Sachse | Method of female hormonal contraception using a fixed extended cycle hormonal preparation containing dienogest and ethinyl estradiol |
EP1655031A1 (de) | 2004-10-08 | 2006-05-10 | Schering AG | Dienogest enthaltendes Langzeit-Verfahren zur Empfängnisverhütung |
US7704984B2 (en) * | 2005-04-22 | 2010-04-27 | Warner Chilcott Company, Llc | Extended estrogen dosing contraceptive regimen |
US8153616B2 (en) | 2005-10-17 | 2012-04-10 | Bayer Pharma Aktiengesellschaft | Combination preparation for oral contraception and oral therapy of dysfunctional uterine bleeding containing estradiol valerate and dienogest and method of using same |
CA2640432A1 (en) * | 2006-01-27 | 2007-08-09 | Duramed Pharmaceuticals, Inc. | Regimens for treatment of conditions related to estrogen deficiency |
ES2558030T3 (es) * | 2006-03-02 | 2016-02-01 | Warner Chilcott Company, Llc | Método anticonceptivo oral multifásico de ciclo prolongado |
EP1930010A1 (de) | 2006-10-20 | 2008-06-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung von Estradiolvalerat oder 17ß-Estradiol in Kombination mit Dienogest zur oralen Therapie für den Erhalt und/oder die Steigerung der weiblichen Libido |
DE202007019049U1 (de) * | 2007-11-05 | 2010-05-12 | Bayer Schering Pharma Aktiengesellschaft | Verwendung eines Gestagens in Kombination mit einem Estrogen zur Prophylaxe der Laktoseintoleranz bei der oralen Kontrazeption |
US20100120707A1 (en) * | 2008-09-16 | 2010-05-13 | Playtex Products, Llc | Dosages for menstrual suppression, contraception, and hormone replacement therapy, and methods of administering same |
US9198876B2 (en) | 2008-10-08 | 2015-12-01 | Agile Therapeutics, Inc. | Contraceptive transdermal delivery of hormones |
CA2740004A1 (en) | 2008-10-08 | 2010-04-15 | Agile Therapeutics, Inc. | Transdermal delivery |
ES2795455T3 (es) | 2008-10-08 | 2020-11-23 | Agile Therapeutics Inc | Suministro transdérmico |
WO2010111488A1 (en) | 2009-03-27 | 2010-09-30 | Agile Therapeutics, Inc. | Transdermal delivery |
MX2017014768A (es) * | 2015-05-18 | 2018-03-23 | Agile Therapeutics Inc | Composiciones anticonceptivas y metodos para mejorar la eficacia y modulacion de los efectos secundarios. |
WO2023037264A1 (en) * | 2021-09-07 | 2023-03-16 | Millicent Pharma Limited | Contraceptive regimen including reduced level of estrogen |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4145416A (en) | 1976-06-23 | 1979-03-20 | Schering, A.G. | Novel agents and novel methods for treatment of climacteric disturbances |
US4390531A (en) * | 1981-08-10 | 1983-06-28 | Syntex Pharmaceuticals International Ltd. | Method of contraception using peak progestogen dosage |
US4826831A (en) | 1983-08-05 | 1989-05-02 | Pre Jay Holdings Limited | Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens |
US4962098A (en) | 1987-06-15 | 1990-10-09 | Warner-Lambert Company | Graduated estrogen contraceptive |
US5208225A (en) * | 1986-02-27 | 1993-05-04 | Warner-Lambert Company | Compositions containing fixed combinations |
IE61236B1 (en) * | 1986-07-15 | 1994-10-19 | American Home Prod | Combination dosage form for pre-menopausal women |
US5108995A (en) * | 1987-09-24 | 1992-04-28 | Jencap Research Ltd. | Hormone preparation and method |
US5098714A (en) * | 1989-11-16 | 1992-03-24 | Alza Corporation | Osmotic, oral dosage form for fertility control |
MX9301121A (es) | 1992-03-02 | 1993-09-01 | Schering Ag | Metodo y equipo para la contracepcion oral y regulacion de la menstruacion con estrogeno/progestina/aniprogestina. |
DE4344462C2 (de) | 1993-12-22 | 1996-02-01 | Schering Ag | Zusammensetzung für die Empfängnisverhütung |
DE4411585A1 (de) * | 1994-03-30 | 1995-10-05 | Schering Ag | Pharmazeutisches Kombinationspräparat zur hormonalen Kontrazeption |
US5552394A (en) * | 1994-07-22 | 1996-09-03 | The Medical College Of Hampton Roads | Low dose oral contraceptives with less breakthrough bleeding and sustained efficacy |
DE19525017A1 (de) * | 1995-06-28 | 1997-01-02 | Schering Ag | Pharmazeutisches Kombinatonspräparat, Kit und Methode zur hormonalen Kontrazeption |
DE19531936A1 (de) | 1995-08-17 | 1997-02-20 | Schering Ag | Kombinationspräparat zur Kontrazeption, Kits diese enthaltend und eine Methode diese verwendend |
AU3888597A (en) | 1996-07-26 | 1998-02-20 | American Home Products Corporation | Oral contraceptive |
US5898032A (en) | 1997-06-23 | 1999-04-27 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with less menstrual bleeding and sustained efficacy |
DE19739916C2 (de) | 1997-09-11 | 2001-09-13 | Hesch Rolf Dieter | Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen |
US6214815B1 (en) | 1998-12-23 | 2001-04-10 | Ortho-Mcneil Pharmaceuticals, Inc. | Triphasic oral contraceptive |
US20030018018A1 (en) | 2001-07-10 | 2003-01-23 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with sustained efficacy and induced amenorrhea |
SI1453521T1 (sl) | 2001-12-05 | 2013-11-29 | Teva Women's Health, Inc. | Oralni kontraceptiki za preprečevanje nosečnosti in zmanjševanje predmenstrualne simptomatike |
US20030219471A1 (en) | 2002-03-11 | 2003-11-27 | Caubel Patrick Michel | Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens |
JP2006525358A (ja) | 2003-05-02 | 2006-11-09 | ドゥラメド ファーマシューティカルズ, インコーポレイテッド | 長期周期避妊養生法を利用するホルモン治療の方法 |
US20040251301A1 (en) | 2003-05-05 | 2004-12-16 | Niemann Amy C. | Device for calculating anticipated days for menstruation |
US20040222123A1 (en) | 2003-05-06 | 2004-11-11 | Barr Laboratories, Inc. | Kit for pharmaceuticals |
RU2403046C2 (ru) | 2003-07-16 | 2010-11-10 | Тева Вимен'С Хелс, Инк. | Способы гормонального лечения с применением контрацептивных режимов с непрерывным введением эстрогена |
NZ546185A (en) | 2003-09-04 | 2008-12-24 | Pharmadesign Inc | Case with pill receiving sleeves for storing and dispensing pills |
WO2005032558A1 (en) | 2003-10-01 | 2005-04-14 | Janssen Pharmaceutica N.V. | Extended triphasic contraceptive regimens |
-
1997
- 1997-06-23 US US08/880,419 patent/US5898032A/en not_active Ceased
-
1998
- 1998-06-15 DE DE69804918T patent/DE69804918T2/de not_active Revoked
- 1998-06-15 ES ES98850109T patent/ES2175650T3/es not_active Expired - Lifetime
- 1998-06-15 EP EP98850109A patent/EP0911029B1/de not_active Revoked
- 1998-06-15 PT PT98850109T patent/PT911029E/pt unknown
- 1998-06-15 AT AT98850109T patent/ATE216241T1/de not_active IP Right Cessation
- 1998-06-15 DK DK98850109T patent/DK0911029T3/da active
- 1998-06-17 JP JP10170390A patent/JPH1129481A/ja active Pending
- 1998-06-18 NO NO982815A patent/NO982815L/no not_active Application Discontinuation
- 1998-12-23 CA CA002256977A patent/CA2256977C/en not_active Expired - Fee Related
-
2004
- 2004-07-19 US US10/893,795 patent/USRE39861E1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0911029A3 (de) | 2000-03-29 |
CA2256977A1 (en) | 2000-06-23 |
PT911029E (pt) | 2002-09-30 |
DE69804918T2 (de) | 2002-11-07 |
JPH1129481A (ja) | 1999-02-02 |
US5898032A (en) | 1999-04-27 |
USRE39861E1 (en) | 2007-09-25 |
DK0911029T3 (da) | 2002-06-17 |
NO982815D0 (no) | 1998-06-18 |
ES2175650T3 (es) | 2002-11-16 |
EP0911029A2 (de) | 1999-04-28 |
NO982815L (no) | 1998-12-28 |
EP0911029B1 (de) | 2002-04-17 |
ATE216241T1 (de) | 2002-05-15 |
CA2256977C (en) | 2008-11-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69804918D1 (de) | Sehr niedrigdosiertes orales Kontrazeptiv mit weniger Menstruationsblutungen und verzögerter Wirkung | |
ES2033850T3 (es) | Forma farmaceutica consistente en una combinacion dosificada, destinada al tratamiento de las mujeres pre-menopausicas. | |
DE68928897D1 (de) | Verfahren und system zur empfängnisverhütung | |
RU96119803A (ru) | Комбинированный препарат для контрацепции на базе природных эстрогенов | |
CY1105276T1 (el) | Τριφασικο στοματικο αντισυλληπτικο | |
NZ333750A (en) | Monophasic contraceptive method and kit comprising a combination of a progestin and estrogen | |
NO2002013I2 (no) | Antikonsepsjonspakke for oral tilforsel | |
HUP9900612A2 (hu) | Új hormonális gyógyászati készítmények, valamint a készítmények alkalmazása ösztrogénpótlásra | |
ATE278406T1 (de) | Orales contrazeptivum |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DURAMED PHARMACEUTICALS, INC., POMONA, N.Y., US |
|
8331 | Complete revocation |