DE69738761D1 - Wechselwirkungen der katalytischen untereinheit der proteinphosphatase 1 - Google Patents

Wechselwirkungen der katalytischen untereinheit der proteinphosphatase 1

Info

Publication number
DE69738761D1
DE69738761D1 DE69738761T DE69738761T DE69738761D1 DE 69738761 D1 DE69738761 D1 DE 69738761D1 DE 69738761 T DE69738761 T DE 69738761T DE 69738761 T DE69738761 T DE 69738761T DE 69738761 D1 DE69738761 D1 DE 69738761D1
Authority
DE
Germany
Prior art keywords
pp1c
fusion
variant
derivative
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69738761T
Other languages
English (en)
Inventor
Philip Cohen
Patricia Cohen
David Barford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medical Research Council
Original Assignee
Medical Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9606765.7A external-priority patent/GB9606765D0/en
Priority claimed from GBGB9626362.9A external-priority patent/GB9626362D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Application granted granted Critical
Publication of DE69738761D1 publication Critical patent/DE69738761D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DE69738761T 1996-03-30 1997-04-01 Wechselwirkungen der katalytischen untereinheit der proteinphosphatase 1 Expired - Fee Related DE69738761D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9606765.7A GB9606765D0 (en) 1996-03-30 1996-03-30 Peptides
GBGB9626362.9A GB9626362D0 (en) 1996-12-19 1996-12-19 Peptides
PCT/GB1997/000898 WO1997037224A1 (en) 1996-03-30 1997-04-01 Protein phosphatase-1 catalytic subunit interactions

Publications (1)

Publication Number Publication Date
DE69738761D1 true DE69738761D1 (de) 2008-07-24

Family

ID=26309031

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69738761T Expired - Fee Related DE69738761D1 (de) 1996-03-30 1997-04-01 Wechselwirkungen der katalytischen untereinheit der proteinphosphatase 1

Country Status (8)

Country Link
US (1) US6884600B1 (de)
EP (1) EP0891551B1 (de)
JP (1) JP2000508761A (de)
AT (1) ATE398287T1 (de)
AU (1) AU722840B2 (de)
CA (1) CA2250826A1 (de)
DE (1) DE69738761D1 (de)
WO (1) WO1997037224A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159704A (en) * 1996-03-29 2000-12-12 Novartis Ag Phosphatase modulator
DE19805334A1 (de) * 1998-02-11 1999-08-12 Otogene Biotechnologische Fors Verfahren zur Entwicklung eines pharmazeutischen Wirkstoffes
GB9818650D0 (en) 1998-08-27 1998-10-21 Medical Res Council Therapeutic compounds and methods of making and using the same
GB9820025D0 (en) * 1998-09-14 1998-11-04 Pfizer Ltd Assay
CA2280276A1 (en) * 1998-09-14 2000-03-14 Pfizer Inc. Assay for detecting modulators of serine/threonine phosphatase activity
EP1728516A1 (de) * 1998-11-02 2006-12-06 The Regents of the University of California Methode zur Hemmung der Phospholamban Aktivität zur Behandlung von Herzkrankheiten und Herzversagen
EP1126866B1 (de) * 1998-11-02 2007-02-07 The Regents of The University of California Eine mutante phospholamban moleküle und deren verwendung zur behandlung von herzkrankheiten und herzversagen
US7399750B2 (en) 2000-09-11 2008-07-15 The Regents Of The University Of California Methods for cardiac gene transfer
ATE345504T1 (de) * 2002-05-07 2006-12-15 Pasteur Institut Screeningverfahren für peptide, die die bindung von pp1c an bcl-2, bcl-xl und bcl-w proteine inhibieren
CN107684828A (zh) * 2017-10-20 2018-02-13 江苏华益科技有限公司 一种高纯氧十六的精馏装置

Also Published As

Publication number Publication date
EP0891551A1 (de) 1999-01-20
JP2000508761A (ja) 2000-07-11
AU2172597A (en) 1997-10-22
WO1997037224A1 (en) 1997-10-09
CA2250826A1 (en) 1997-10-09
EP0891551B1 (de) 2008-06-11
US6884600B1 (en) 2005-04-26
AU722840B2 (en) 2000-08-10
ATE398287T1 (de) 2008-07-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee