DE69738124D1 - Verfahren zur Herstellung von hochmonodispersierten Polymeren hydrophiler Nanopartikel - Google Patents

Verfahren zur Herstellung von hochmonodispersierten Polymeren hydrophiler Nanopartikel

Info

Publication number
DE69738124D1
DE69738124D1 DE69738124T DE69738124T DE69738124D1 DE 69738124 D1 DE69738124 D1 DE 69738124D1 DE 69738124 T DE69738124 T DE 69738124T DE 69738124 T DE69738124 T DE 69738124T DE 69738124 D1 DE69738124 D1 DE 69738124D1
Authority
DE
Germany
Prior art keywords
preparation
hydrophilic nanoparticles
highly monodispersed
monodispersed polymers
polymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69738124T
Other languages
English (en)
Other versions
DE69738124T2 (de
Inventor
Amarnath Maitra
P K Ghosh
K Tapas De
Sanjeeb Kumar Sahoo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69738124D1 publication Critical patent/DE69738124D1/de
Publication of DE69738124T2 publication Critical patent/DE69738124T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DE1997638124 1997-05-08 1997-05-08 Verfahren zur Herstellung von hochmonodisperser, Polymeren, hydrophiler Nanopartikel Expired - Fee Related DE69738124T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97303127A EP0877033B1 (de) 1997-05-08 1997-05-08 Verfahren zur Herstellung von hochmonodispersierten Polymeren hydrophiler Nanopartikel

Publications (2)

Publication Number Publication Date
DE69738124D1 true DE69738124D1 (de) 2007-10-25
DE69738124T2 DE69738124T2 (de) 2008-06-12

Family

ID=8229320

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1997638124 Expired - Fee Related DE69738124T2 (de) 1997-05-08 1997-05-08 Verfahren zur Herstellung von hochmonodisperser, Polymeren, hydrophiler Nanopartikel

Country Status (2)

Country Link
EP (1) EP0877033B1 (de)
DE (1) DE69738124T2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2319437C (en) 1998-01-31 2009-06-16 University Of Arkansas Methods and reagents for decreasing allergic reactions
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
US8246945B2 (en) 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
DK1272213T3 (da) 2000-04-06 2006-07-10 Seer Pharmaceuticals Llc Mikrobielt afgivelsessystem
GB0009773D0 (en) * 2000-04-19 2000-06-07 Univ Cardiff Particulate composition
CA2309575A1 (en) * 2000-05-26 2001-11-26 James E. Guillet Internally cross-linked macromolecules
AU2005304567B2 (en) 2004-11-12 2011-10-27 Mayo Foundation For Medical Education And Research Photocrosslinkable poly(caprolactone fumarate)
EP1877000B1 (de) * 2005-03-23 2012-10-17 Mayo Foundation For Medical Education And Research Durch licht quervernetzbare oligo-(polyethylenglykolfumarat)-hydrogele zur zuführung von zellen und arzneistoffen
WO2006118987A1 (en) 2005-04-29 2006-11-09 Mayo Foundation For Medical Education And Research Hydrophilic/hydrophobic polymer networks based on poly(caprolactone fumarate), poly(ethylene glycol fumarate), and copolymers thereof
US8974827B2 (en) 2007-06-04 2015-03-10 Bend Research, Inc. Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2240162A4 (de) 2007-12-06 2013-10-09 Bend Res Inc Nanoteilchen mit einem nicht-ionisierbaren polymer und einem amin-funktionalisierten methacrylat-copolymer
EP2231169B1 (de) 2007-12-06 2016-05-04 Bend Research, Inc. Pharmazeutische zusammensetzungen mit nanopartikeln und resuspensionsmaterial
KR101113044B1 (ko) * 2008-08-29 2012-02-27 동국제약 주식회사 용매교류증발법에 의한 서방출성 미립구의 제조방법
EP2201935B1 (de) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymere Mizellenzusammensetzung, die ein schlecht lösliches Arzneimittel enthält, und zugehöriges Herstellungsverfahren
CN102264350A (zh) * 2008-12-26 2011-11-30 株式会社三养社 包含水溶性差的药物的聚合胶束纳米粒子组合物的制备方法
US20170112777A1 (en) * 2014-05-16 2017-04-27 Dana-Farber Cancer Institute, Inc. Protein-based particles for drug delivery

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH594444A5 (de) * 1972-12-04 1978-01-13 Gerd Birrenbach

Also Published As

Publication number Publication date
EP0877033A1 (de) 1998-11-11
DE69738124T2 (de) 2008-06-12
EP0877033B1 (de) 2007-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee