DE69737888D1 - Anti-mhc klasse ii bindungsreagentien zur verwendung bei xenotransplantationen - Google Patents

Anti-mhc klasse ii bindungsreagentien zur verwendung bei xenotransplantationen

Info

Publication number
DE69737888D1
DE69737888D1 DE69737888T DE69737888T DE69737888D1 DE 69737888 D1 DE69737888 D1 DE 69737888D1 DE 69737888 T DE69737888 T DE 69737888T DE 69737888 T DE69737888 T DE 69737888T DE 69737888 D1 DE69737888 D1 DE 69737888D1
Authority
DE
Germany
Prior art keywords
xenotransplantations
mhc class
binding reagents
reagents
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69737888T
Other languages
English (en)
Other versions
DE69737888T2 (de
Inventor
Nina Elizabeth Saxton
Roland Foulkes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Application granted granted Critical
Publication of DE69737888D1 publication Critical patent/DE69737888D1/de
Publication of DE69737888T2 publication Critical patent/DE69737888T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69737888T 1996-09-24 1997-09-24 Anti-mhc klasse ii bindungsreagentien zur verwendung bei xenotransplantationen Expired - Fee Related DE69737888T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9619894 1996-09-24
GBGB9619894.0A GB9619894D0 (en) 1996-09-24 1996-09-24 Pharmaceutical products
PCT/GB1997/002599 WO1998013066A1 (en) 1996-09-24 1997-09-24 Anti-class ii mhc binding agents for use in xenotransplantation

Publications (2)

Publication Number Publication Date
DE69737888D1 true DE69737888D1 (de) 2007-08-16
DE69737888T2 DE69737888T2 (de) 2008-04-03

Family

ID=10800412

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737888T Expired - Fee Related DE69737888T2 (de) 1996-09-24 1997-09-24 Anti-mhc klasse ii bindungsreagentien zur verwendung bei xenotransplantationen

Country Status (6)

Country Link
EP (1) EP0942750B1 (de)
JP (1) JP2001500892A (de)
AU (1) AU4314597A (de)
DE (1) DE69737888T2 (de)
GB (1) GB9619894D0 (de)
WO (1) WO1998013066A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69834038D1 (de) 1997-07-01 2006-05-18 Isis Pharmaceutical Inc Zusammensetzungen und verfahren zur verabreichung von oligonukleotiden über die speiseröhre
JP2003524586A (ja) * 1998-05-21 2003-08-19 アイシス・ファーマシューティカルス・インコーポレーテッド オリゴヌクレオチドの非−非経口投与のための組成物と方法
GB0201896D0 (en) * 2002-01-28 2002-03-13 Ice Biolog Ltd Treatment
MXPA04000147A (es) * 2001-07-02 2005-01-07 Aimsco Ltd Agente terapeutico.
ES2266564T3 (es) 2001-10-19 2007-03-01 Isotechnika Inc. Sintesis de analogos de cicloporinas.
EP1469882B1 (de) * 2002-01-28 2010-08-25 Aimsco Limited Behandlung von krankheiten des nervensystems mit ziegenserum
WO2013043800A1 (en) * 2011-09-22 2013-03-28 Immunomedics, Inc. Anti-hla-dr antibodies suppress allogeneic and xenogeneic immune responses to organ transplants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU695120B2 (en) * 1993-06-07 1998-08-06 Baylor College Of Medicine Use of an MHC class I suppressor drug for the treatment of autoimmune diseases and transplantation rejection
CA2217131A1 (en) * 1995-04-20 1996-12-05 Diacrin, Incorporated Modified cells and methods for inhibiting xenograft rejection

Also Published As

Publication number Publication date
EP0942750A1 (de) 1999-09-22
DE69737888T2 (de) 2008-04-03
JP2001500892A (ja) 2001-01-23
WO1998013066A1 (en) 1998-04-02
AU4314597A (en) 1998-04-17
EP0942750B1 (de) 2007-07-04
GB9619894D0 (en) 1996-11-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee