DE69734520D1 - Nukleinsäurevermittelter elektronentransfer - Google Patents
Nukleinsäurevermittelter elektronentransferInfo
- Publication number
- DE69734520D1 DE69734520D1 DE69734520T DE69734520T DE69734520D1 DE 69734520 D1 DE69734520 D1 DE 69734520D1 DE 69734520 T DE69734520 T DE 69734520T DE 69734520 T DE69734520 T DE 69734520T DE 69734520 D1 DE69734520 D1 DE 69734520D1
- Authority
- DE
- Germany
- Prior art keywords
- nucleic acid
- complexes
- electron transfer
- reduced electron
- moieties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65998796A | 1996-06-07 | 1996-06-07 | |
PCT/US1997/009739 WO1997046568A1 (en) | 1996-06-07 | 1997-06-04 | Nucleic acid mediated electron transfer |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69734520D1 true DE69734520D1 (de) | 2005-12-08 |
Family
ID=24647650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69734520T Expired - Lifetime DE69734520D1 (de) | 1996-06-07 | 1997-06-04 | Nukleinsäurevermittelter elektronentransfer |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0923595B1 (de) |
JP (1) | JP2000511904A (de) |
AT (1) | ATE308553T1 (de) |
AU (1) | AU738189B2 (de) |
CA (1) | CA2257534A1 (de) |
DE (1) | DE69734520D1 (de) |
WO (1) | WO1997046568A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6071699A (en) | 1996-06-07 | 2000-06-06 | California Institute Of Technology | Nucleic acid mediated electron transfer |
US5620850A (en) | 1994-09-26 | 1997-04-15 | President And Fellows Of Harvard College | Molecular recognition at surfaces derivatized with self-assembled monolayers |
US7381525B1 (en) | 1997-03-07 | 2008-06-03 | Clinical Micro Sensors, Inc. | AC/DC voltage apparatus for detection of nucleic acids |
US7014992B1 (en) | 1996-11-05 | 2006-03-21 | Clinical Micro Sensors, Inc. | Conductive oligomers attached to electrodes and nucleoside analogs |
JP2002508386A (ja) * | 1997-12-16 | 2002-03-19 | ザ・ユニバーシティー・オブ・サスカチワン・テクノロジーズ・インコーポレーテッド | 導電性金属含有核酸 |
CA2229386A1 (en) * | 1997-12-16 | 1999-06-16 | The University Of Saskatchewan | Conductive metal-containing nucleic acids |
EP1090286A1 (de) * | 1998-06-24 | 2001-04-11 | Therasense, Inc. | Mehrfacher sensorgruppe zur electrochemischer erkennung von nukleotidsequenzen und verfahren |
US6740518B1 (en) | 1998-09-17 | 2004-05-25 | Clinical Micro Sensors, Inc. | Signal detection techniques for the detection of analytes |
WO2000024941A1 (en) | 1998-10-27 | 2000-05-04 | Clinical Micro Sensors, Inc. | Detection of target analytes using particles and electrodes |
US20020004593A1 (en) * | 1998-11-13 | 2002-01-10 | Thomas J. Meade | Methods of making modified nucleosides |
DE19964220C2 (de) | 1998-11-23 | 2003-07-03 | Friz Biochem Gmbh | Verfahren zur Herstellung einer modifizierten leitfähigen Oberfläche |
US7160869B2 (en) | 1998-12-16 | 2007-01-09 | University Of Saskatchewan | Biologically active metal-containing nucleic acids |
DE19901761A1 (de) * | 1999-01-18 | 1999-07-01 | Gerhard Dr Hartwich | Verfahren zur elektrochemischen Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen |
US6787339B1 (en) | 2000-10-02 | 2004-09-07 | Motorola, Inc. | Microfluidic devices having embedded metal conductors and methods of fabricating said devices |
WO2003018834A2 (de) | 2001-08-25 | 2003-03-06 | Friz Biochem Gmbh | Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen |
DE60239748D1 (de) | 2001-09-14 | 2011-05-26 | Arkray Inc | Verfahren, gerät und vorrichtung zur konzentrationsmessung |
GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
JP2009536525A (ja) | 2006-05-10 | 2009-10-15 | ディクステリティー ダイアグノーティクス | 化学反応性オリゴヌクレオチドプローブを使用した核酸標的の検出 |
EP2765205B1 (de) | 2009-04-01 | 2016-05-18 | DxTerity Diagnostics Incorporated | Chemische ligationsabhängige Sondenamplifizierung (CLPA) |
DK2710145T3 (en) | 2011-05-17 | 2016-02-22 | Dxterity Diagnostics Inc | METHOD AND COMPOSITIONS FOR THE DETECTION OF TARGET NUCLEIC ACIDS |
AU2015274660B2 (en) | 2014-06-10 | 2020-07-16 | Dxterity Diagnostics Incorporated | Devices and methods for collecting and stabilizing biological samples |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5112974A (en) * | 1985-01-18 | 1992-05-12 | The Trustees Of Columbia University In The City Of New York | Mixed ligand complexes and uses thereof as binding agents to DNA |
JPS63238166A (ja) * | 1987-03-26 | 1988-10-04 | Mitsubishi Electric Corp | 有機電子素子材料 |
CA2094785A1 (en) * | 1992-05-08 | 1993-11-09 | Jean Gariepy | Metal chelating peptide |
US5591578A (en) * | 1993-12-10 | 1997-01-07 | California Institute Of Technology | Nucleic acid mediated electron transfer |
JP2000501601A (ja) * | 1995-06-27 | 2000-02-15 | ザ ユニヴァーシティ オブ ノース カロライナ アット チャペル ヒル | 核酸ハイブリッド形成の電気化学的検出 |
-
1997
- 1997-06-04 JP JP10500855A patent/JP2000511904A/ja not_active Ceased
- 1997-06-04 AT AT97928853T patent/ATE308553T1/de not_active IP Right Cessation
- 1997-06-04 WO PCT/US1997/009739 patent/WO1997046568A1/en active IP Right Grant
- 1997-06-04 DE DE69734520T patent/DE69734520D1/de not_active Expired - Lifetime
- 1997-06-04 AU AU33014/97A patent/AU738189B2/en not_active Ceased
- 1997-06-04 CA CA002257534A patent/CA2257534A1/en not_active Abandoned
- 1997-06-04 EP EP97928853A patent/EP0923595B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2000511904A (ja) | 2000-09-12 |
EP0923595A1 (de) | 1999-06-23 |
AU738189B2 (en) | 2001-09-13 |
AU3301497A (en) | 1998-01-05 |
WO1997046568A1 (en) | 1997-12-11 |
CA2257534A1 (en) | 1997-12-11 |
ATE308553T1 (de) | 2005-11-15 |
EP0923595B1 (de) | 2005-11-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |