DE69734464D1 - Verfahren zur expression und herstellung von rekombinantem, menschlichem beta-cis-interferon - Google Patents

Verfahren zur expression und herstellung von rekombinantem, menschlichem beta-cis-interferon

Info

Publication number
DE69734464D1
DE69734464D1 DE69734464T DE69734464T DE69734464D1 DE 69734464 D1 DE69734464 D1 DE 69734464D1 DE 69734464 T DE69734464 T DE 69734464T DE 69734464 T DE69734464 T DE 69734464T DE 69734464 D1 DE69734464 D1 DE 69734464D1
Authority
DE
Germany
Prior art keywords
interferon
cis
expressing
human beta
producing recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69734464T
Other languages
English (en)
Other versions
DE69734464T2 (de
Inventor
Ferreira Paulo Cesar Peregrino
Kroon Erna Geessien
Rolland Golgher
Antonio Bonjardim
Carvalho Fiorini De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidade Federal de Minas Gerais
Original Assignee
Universidade Federal de Minas Gerais
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidade Federal de Minas Gerais filed Critical Universidade Federal de Minas Gerais
Application granted granted Critical
Publication of DE69734464D1 publication Critical patent/DE69734464D1/de
Publication of DE69734464T2 publication Critical patent/DE69734464T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69734464T 1996-12-18 1997-12-19 Verfahren zur expression und herstellung von rekombinantem, menschlichem beta-cis-interferon Expired - Lifetime DE69734464T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BR9606270 1996-12-18
BR9606270A BR9606270A (pt) 1996-12-18 1996-12-18 Processo para a produção da proteína do interferon beta-cis humano recombinante e proteína de interferon beta-cis humano recombinante
PCT/BR1997/000082 WO1998027211A1 (en) 1996-12-18 1997-12-19 The process for the expression and production of the recombinant human beta-cis interferon

Publications (2)

Publication Number Publication Date
DE69734464D1 true DE69734464D1 (de) 2005-12-01
DE69734464T2 DE69734464T2 (de) 2006-08-03

Family

ID=4065945

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69734464T Expired - Lifetime DE69734464T2 (de) 1996-12-18 1997-12-19 Verfahren zur expression und herstellung von rekombinantem, menschlichem beta-cis-interferon

Country Status (5)

Country Link
US (1) US6323006B1 (de)
EP (1) EP0963437B1 (de)
BR (1) BR9606270A (de)
DE (1) DE69734464T2 (de)
WO (1) WO1998027211A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
EP1881005B1 (de) * 1997-07-14 2013-04-03 Bolder Biotechnology, Inc. Derivate von G-CSF und damit zusammenhängende Proteine
US6753165B1 (en) * 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US7544354B2 (en) 2000-10-27 2009-06-09 Novartis Vaccines And Diagnostics Methods of protein purification and recovery
EP2298354B1 (de) 2001-10-10 2014-03-19 ratiopharm GmbH Neumodulierung und Glykokonjugation von Interferon-beta
EP2292271A3 (de) 2001-10-10 2011-09-14 BioGeneriX AG Neumodulierung und Glykokonjugation von Antikörpern
KR100511749B1 (ko) * 2001-11-06 2005-09-02 선바이오(주) 변형된 인터페론-베타, 및 이의 화학적으로 변형된 배합체
AU2003263552A1 (en) * 2002-09-09 2004-03-29 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
PL1615945T3 (pl) 2003-04-09 2012-03-30 Ratiopharm Gmbh Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami
AU2008201682B2 (en) * 2004-02-02 2011-02-24 Ambrx, Inc. Modified human interferon polypeptides and their uses
AU2005211385B2 (en) 2004-02-02 2008-12-11 Ambrx, Inc. Modified human growth hormone polypeptides and their uses
US20080003202A1 (en) * 2006-03-28 2008-01-03 Thierry Guyon Modified interferon-beta (IFN-beta) polypeptides
CA2685596A1 (en) 2007-05-02 2008-11-13 Ambrx, Inc. Modified interferon beta polypeptides and their uses
JP5702150B2 (ja) 2008-02-08 2015-04-15 アンブルックス, インコーポレイテッドAmbrx, Inc. 修飾されているレプチンポリペプチドおよびそれらの使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
EP0355190A1 (de) * 1988-08-24 1990-02-28 Tadatsugu Dr. Taniguchi Genexpression regulierender Faktor
US5166322A (en) * 1989-04-21 1992-11-24 Genetics Institute Cysteine added variants of interleukin-3 and chemical modifications thereof

Also Published As

Publication number Publication date
US6323006B1 (en) 2001-11-27
BR9606270A (pt) 1998-09-22
EP0963437B1 (de) 2005-10-26
WO1998027211A1 (en) 1998-06-25
DE69734464T2 (de) 2006-08-03
EP0963437A1 (de) 1999-12-15

Similar Documents

Publication Publication Date Title
ATE258180T1 (de) Verfahren zur herstellung von glufosinate und zwischenprodukte dafür
DE68922726T2 (de) Medizinisches material und verfahren zur herstellung.
DE69535674D1 (de) Verfahren zur herstellung von l-valin und l-leucin
DE69533987D1 (de) Protein oder polypeptid, verfahren zur seiner herstellung und entsprechende zwischenprodukte
DE69736247D1 (de) Verfahren zur herstellung von proteinhydrolysate
DE69734464D1 (de) Verfahren zur expression und herstellung von rekombinantem, menschlichem beta-cis-interferon
DE69419005T2 (de) Verfahren zur herstellung von 1,1,1,4,4,4-hexafluoro-2-butenen und 1,1,4,4,4,4-hexafluorobutan
DE69329923T2 (de) Molkenprotein und molkenproteinhydrolysate, und verfahren zur herstellung
ATE204291T1 (de) Verfahren zur herstellung von peptiden und n- carbamoyl-geschützten peptiden
ATE219767T1 (de) Verfahren zur herstellung von 2,4-dihydroxy- pyridin und 2,4-dihydroxy-3-nitropyridin
DE69707607D1 (de) Enzymbehandeltes Hesperidin, Verfahren zur Herstellung und Verfahren zur Verwendung von enzymbehandeltem Hesperidin
DE69619209T2 (de) Verfahren zur herstellung von alkoxylierungskatalysatoren und alkoxylierungsverfahren
DE69321848D1 (de) Verfahren zur herstellung von 1,1,1,2,3,3-hexafluorpropan und von tetrafluorchlorpropen
DE69613964T2 (de) Verfahren zur herstellung von pentafluoroethan und tetrafluorochloroethan
ATE258558T1 (de) Lantibiotikum verwandt mit actagardine, verfahren zur herstellung und verwendung desselben
ATE240324T1 (de) Verbessertes verfahren zur herstellung von thiazolidindionen und neue thiazolidindione
DE69706976T2 (de) Kontinuierliches verfahren zur herstellung von hydrocarbylaluminoxanen
DE69522561T2 (de) Verfahren zur herstellung von benzophentionen und benzophenonen
DE69431396T2 (de) Verfahren zur herstellung von n-tert-butyl-2-pyrazincarboxamid und n-tert-butyl-2-piperazincarboxamid
DE69419516T2 (de) Verfahren zur herstellung von hexafluorocyclobuten und verfahren zur herstellung von hexafluorocyclobutan
DE69505632D1 (de) Verfahren zur herstellung von cycloalkanolen und cycloalkanonen
DE69617643D1 (de) Verfahren zur herstellung von difluormethan und difluorchlormethan
DE69840863D1 (de) Verfahren zur Herstellung von 2,6-Diaminopurin-2'deoxyribosid und 2'-Deoxyguanosin
DE59700696D1 (de) Verfahren und zwischenprodukte zur herstellung von pyridyl-4-fluoranilinen
ATA110696A (de) Verfahren zur gewinnung und reinigung von rekombinantem, nicht-lipidiertem osp-protein

Legal Events

Date Code Title Description
8364 No opposition during term of opposition