DE69708425D1 - Makrophagen infizierende Parasiten, die ein Leukozyten- und Makrophagen-stimulierendes Hormon exprimieren - Google Patents
Makrophagen infizierende Parasiten, die ein Leukozyten- und Makrophagen-stimulierendes Hormon exprimierenInfo
- Publication number
- DE69708425D1 DE69708425D1 DE69708425T DE69708425T DE69708425D1 DE 69708425 D1 DE69708425 D1 DE 69708425D1 DE 69708425 T DE69708425 T DE 69708425T DE 69708425 T DE69708425 T DE 69708425T DE 69708425 D1 DE69708425 D1 DE 69708425D1
- Authority
- DE
- Germany
- Prior art keywords
- macrophage
- parasites
- express
- leishmania
- leukocyte
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 244000045947 parasite Species 0.000 title abstract 6
- 210000002540 macrophage Anatomy 0.000 title abstract 3
- 229940088597 hormone Drugs 0.000 title 1
- 239000005556 hormone Substances 0.000 title 1
- 210000000265 leukocyte Anatomy 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
- 241000222722 Leishmania <genus> Species 0.000 abstract 3
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 108010017213 Granulocyte-Macrophage Colony-Stimulating Factor Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001018 virulence Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/713,768 US6331304B1 (en) | 1996-09-13 | 1996-09-13 | Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulating factor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69708425D1 true DE69708425D1 (de) | 2002-01-03 |
DE69708425T2 DE69708425T2 (de) | 2002-05-23 |
Family
ID=24867467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69708425T Expired - Lifetime DE69708425T2 (de) | 1996-09-13 | 1997-09-12 | Makrophagen infizierende Parasiten, die ein Leukozyten- und Makrophagen-stimulierendes Hormon exprimieren |
Country Status (8)
Country | Link |
---|---|
US (1) | US6331304B1 (de) |
EP (1) | EP0829540B1 (de) |
AT (1) | ATE209253T1 (de) |
CA (1) | CA2215641C (de) |
DE (1) | DE69708425T2 (de) |
DK (1) | DK0829540T3 (de) |
ES (1) | ES2168583T3 (de) |
PT (1) | PT829540E (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6855537B1 (en) * | 1996-09-13 | 2005-02-15 | Aventis Pasteur Limited | Macrophage-infecting parasites expressing a granulocyte macrophage colony stimulated factor |
GB9706930D0 (en) * | 1997-04-04 | 1997-05-21 | Univ Glasgow | Leishmania vaccine |
US6368827B1 (en) * | 1998-12-02 | 2002-04-09 | The University Of Georgia Research Foundation, Inc. | Kinetoplastid protein expression system and methods |
US20010010928A1 (en) * | 1999-03-26 | 2001-08-02 | Stephen M. Beverley | Protozoan expression system |
WO2002090556A1 (en) * | 2001-05-08 | 2002-11-14 | Jena Bioscience Gmbh | Method for targeted homologous gene replacement in kinetoplastidae |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE236252T1 (de) * | 1993-09-03 | 2003-04-15 | Univ Mcgill | Differentiell exprimierte leishmania gene und proteinen |
-
1996
- 1996-09-13 US US08/713,768 patent/US6331304B1/en not_active Expired - Lifetime
-
1997
- 1997-09-11 CA CA002215641A patent/CA2215641C/en not_active Expired - Fee Related
- 1997-09-12 DK DK97307081T patent/DK0829540T3/da active
- 1997-09-12 DE DE69708425T patent/DE69708425T2/de not_active Expired - Lifetime
- 1997-09-12 ES ES97307081T patent/ES2168583T3/es not_active Expired - Lifetime
- 1997-09-12 AT AT97307081T patent/ATE209253T1/de active
- 1997-09-12 EP EP97307081A patent/EP0829540B1/de not_active Expired - Lifetime
- 1997-09-12 PT PT97307081T patent/PT829540E/pt unknown
Also Published As
Publication number | Publication date |
---|---|
EP0829540B1 (de) | 2001-11-21 |
EP0829540A1 (de) | 1998-03-18 |
ATE209253T1 (de) | 2001-12-15 |
CA2215641C (en) | 2009-07-07 |
DE69708425T2 (de) | 2002-05-23 |
DK0829540T3 (da) | 2002-05-21 |
PT829540E (pt) | 2002-05-31 |
CA2215641A1 (en) | 1998-03-13 |
ES2168583T3 (es) | 2002-06-16 |
US6331304B1 (en) | 2001-12-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |