MXPA02010173A - Antigenos de leishmania para utilizarse en la terapia y el diagnostico de leishmaniasis. - Google Patents

Antigenos de leishmania para utilizarse en la terapia y el diagnostico de leishmaniasis.

Info

Publication number
MXPA02010173A
MXPA02010173A MXPA02010173A MXPA02010173A MXPA02010173A MX PA02010173 A MXPA02010173 A MX PA02010173A MX PA02010173 A MXPA02010173 A MX PA02010173A MX PA02010173 A MXPA02010173 A MX PA02010173A MX PA02010173 A MXPA02010173 A MX PA02010173A
Authority
MX
Mexico
Prior art keywords
polypeptides
leishmania
leishmaniasis
compositions
vaccines
Prior art date
Application number
MXPA02010173A
Other languages
English (en)
Inventor
Peter Probst
Original Assignee
Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/551,974 external-priority patent/US6500437B1/en
Priority claimed from US09/565,501 external-priority patent/US6607731B1/en
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of MXPA02010173A publication Critical patent/MXPA02010173A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen composiciones y métodos para prevenir, tratar y detectar Leishmaniasis y estimular respuestas inmunes en pacientes. Los compuestos provistos incluyen polipéptidos que contienen por lo menos una porcion inmunogenica de uno o más antígenos de Leishmania, o de una variante del mismo. También se proporcionan vacunas y composiciones farmacéuticas que comprenden dichos polipéptidos, o polinucleotidos que codifican dichos polipéptidos, y se pueden utilizar, por ejemplo, para la prevencion y terapia de leishmaniasis, así como para la deteccion de una infeccion por Leishmania.
MXPA02010173A 2000-04-14 2001-04-05 Antigenos de leishmania para utilizarse en la terapia y el diagnostico de leishmaniasis. MXPA02010173A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/551,974 US6500437B1 (en) 1995-09-22 2000-04-14 Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
US09/565,501 US6607731B1 (en) 1995-09-22 2000-05-05 Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
US09/639,206 US6613337B1 (en) 1997-02-12 2000-08-14 Leishmania antigens for use in the therapy and diagnosis of leishmaniasis
PCT/US2001/011254 WO2001079276A2 (en) 2000-04-14 2001-04-05 Leishmania antigens for use in the therapy and diagnosis of leishmaniasis

Publications (1)

Publication Number Publication Date
MXPA02010173A true MXPA02010173A (es) 2003-06-04

Family

ID=27415636

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02010173A MXPA02010173A (es) 2000-04-14 2001-04-05 Antigenos de leishmania para utilizarse en la terapia y el diagnostico de leishmaniasis.

Country Status (10)

Country Link
US (1) US6613337B1 (es)
EP (2) EP1287026B1 (es)
AR (1) AR028333A1 (es)
AT (1) ATE310746T1 (es)
AU (1) AU2001255241A1 (es)
DE (1) DE60115230T2 (es)
ES (2) ES2391562T3 (es)
MX (1) MXPA02010173A (es)
PT (1) PT1681301E (es)
WO (1) WO2001079276A2 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ515322A (en) 1999-05-13 2004-03-26 Wyeth Corp Adjuvant combination formulations
EP1255562B1 (en) * 2000-02-18 2008-01-16 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. Use of opri lipoprotein from pseudomonas as a th1 inducing natural adjuvant for heterologous antigens
CZ20031225A3 (cs) * 2000-11-10 2003-10-15 Wyeth Holdings Corporation Adjuvantní kombinované prostředky
BRPI0710155A2 (pt) 2006-04-10 2011-08-23 Infectious Disease Res Inst Inc compostos e métodos para diagnóstico e tratamento de leishmaniose
WO2009012166A1 (en) * 2007-07-13 2009-01-22 Infectious Disease Research Institute Leishmania sterol 24-c-methyltransferase compositions for the prevention, treatment and diagnosis of leishmaniasis
US8410258B2 (en) 2008-05-21 2013-04-02 Infections Disease Research Institute Recombinant polyprotein vaccines for the treatment and diagnosis of leishmaniasis
BRPI0912768A2 (pt) 2008-05-21 2016-05-17 Infectious Disease Res Inst vacinas de poliproteínas recombinante para o tratamento e diagnóstico de leishmaniose
US8231881B2 (en) 2008-07-03 2012-07-31 Infectious Disease Research Institute Fusion proteins and their use in the diagnosis and treatment of leishmaniasis
BRPI0900961B8 (pt) * 2009-03-23 2021-07-13 Fundacao Oswaldo Cruz métodos e kit para diagnóstico de leishmaniose
CN102483413A (zh) * 2009-07-13 2012-05-30 热体实验室有限公司 使用核糖体蛋白提取物（rpe）的寄生虫病如利什曼病的诊断
WO2014091463A1 (pt) * 2012-12-14 2014-06-19 Universidade Federal De Minas Gerais - Ufmg Processo para produção de proteínas recombinantes de leishmania e uso em kit para diagnóstico e vacina contra leishmanioses
ES2728865T3 (es) 2013-03-28 2019-10-29 Infectious Disease Res Inst Vacunas que comprenden polipéptidos de Leishmania para el tratamiento y el diagnóstico de la leishmaniasis
US20140356391A1 (en) * 2013-05-29 2014-12-04 Jose Antonio O'Daly Amino acid sequences for clinical remission of psoriasis and related diseases.
JP2016053535A (ja) * 2014-09-04 2016-04-14 国立大学法人 東京大学 皮膚型リーシュマニア症の検査用試薬又はキット、及び皮膚型リーシュマニア症の検査方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4870006A (en) 1986-07-24 1989-09-26 Codon Antigenic material for a chagas' disease detection system
US5411865A (en) 1993-01-15 1995-05-02 Iasys Corporation Method of detecting anti-leishmania parasite antibodies
US5961970A (en) 1993-10-29 1999-10-05 Pharmos Corporation Submicron emulsions as vaccine adjuvants
US5571515A (en) 1994-04-18 1996-11-05 The Wistar Institute Of Anatomy & Biology Compositions and methods for use of IL-12 as an adjuvant
PT804581E (pt) 1994-04-22 2002-02-28 Corixa Corp Compostos e metodos para a estimulacao e reforco das respostas imunitarias protectoras e da producao de il-12
US6013268A (en) 1994-04-22 2000-01-11 Corixa Corporation Methods for enhancement of protective immune responses
US5879687A (en) 1994-04-22 1999-03-09 Corixa Corporation Methods for enhancement of protective immune responses
US5876735A (en) 1994-04-22 1999-03-02 Corixa Corporation Methods for enhancement of protective immune responses
US5912166A (en) 1995-04-21 1999-06-15 Corixa Corporation Compounds and methods for diagnosis of leishmaniasis
US5965142A (en) 1995-08-04 1999-10-12 Corixa Corporation Polypeptides and methods for the detection of L. tropica infection
US5834592A (en) 1995-09-22 1998-11-10 Corixa Corporation Leishmania antigens for use in the therapy and diagnosis of Leishmaniasis
US5744593A (en) * 1996-02-15 1998-04-28 Heska Corporation Parasitic helminth larval thiol specific antioxidant proteins and nucleic acid molecules
US5910306A (en) 1996-11-14 1999-06-08 The United States Of America As Represented By The Secretary Of The Army Transdermal delivery system for antigen
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US5846748A (en) 1996-11-15 1998-12-08 The Council Of Scientific & Industrial Research Method for diagnosing visceral leishmaniasis in a patient by identification of a new key marker namely 9-O-acetylated sialoglycoconjugate
BR9807332A (pt) 1997-02-12 2000-10-31 Corixa Corp Antìgenos de leishmania para utilização na terapia e diagnóstico de leishmaniose
DE69931518T2 (de) * 1998-12-23 2006-12-21 C.B.F. Leti, S.A., Tres Cantos Chimäres Gen, das für die antigenischen Determinaten von vier Proteinen aus L. Infantum kodiert

Also Published As

Publication number Publication date
EP1287026B1 (en) 2005-11-23
ES2391562T3 (es) 2012-11-27
ES2255553T3 (es) 2006-07-01
WO2001079276A2 (en) 2001-10-25
AU2001255241A1 (en) 2001-10-30
EP1681301A1 (en) 2006-07-19
EP1287026A2 (en) 2003-03-05
PT1681301E (pt) 2012-10-26
ATE310746T1 (de) 2005-12-15
US6613337B1 (en) 2003-09-02
DE60115230D1 (de) 2005-12-29
DE60115230T2 (de) 2006-08-03
WO2001079276A3 (en) 2002-09-06
EP1681301B1 (en) 2012-07-18
AR028333A1 (es) 2003-05-07

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