DE69708126T2 - Verfahren zur herstellung von paclitaxel - Google Patents
Verfahren zur herstellung von paclitaxelInfo
- Publication number
- DE69708126T2 DE69708126T2 DE69708126T DE69708126T DE69708126T2 DE 69708126 T2 DE69708126 T2 DE 69708126T2 DE 69708126 T DE69708126 T DE 69708126T DE 69708126 T DE69708126 T DE 69708126T DE 69708126 T2 DE69708126 T2 DE 69708126T2
- Authority
- DE
- Germany
- Prior art keywords
- producing paclitaxel
- paclitaxel
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19960035754 | 1996-08-27 | ||
| PCT/KR1997/000157 WO1998008832A1 (en) | 1996-08-27 | 1997-08-25 | Process for preparing paclitaxel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69708126D1 DE69708126D1 (de) | 2001-12-13 |
| DE69708126T2 true DE69708126T2 (de) | 2002-07-11 |
Family
ID=19470938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69708126T Expired - Lifetime DE69708126T2 (de) | 1996-08-27 | 1997-08-25 | Verfahren zur herstellung von paclitaxel |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6130336A (de) |
| EP (1) | EP0923565B1 (de) |
| JP (1) | JP3294280B2 (de) |
| KR (1) | KR100225535B1 (de) |
| AR (1) | AR009349A1 (de) |
| AT (1) | ATE208383T1 (de) |
| AU (1) | AU3953297A (de) |
| DE (1) | DE69708126T2 (de) |
| DK (1) | DK0923565T3 (de) |
| ES (1) | ES2167777T3 (de) |
| ID (1) | ID19799A (de) |
| IL (1) | IL121599A (de) |
| PT (1) | PT923565E (de) |
| TR (1) | TR199700863A2 (de) |
| WO (1) | WO1998008832A1 (de) |
| YU (1) | YU35997A (de) |
| ZA (1) | ZA977596B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5917062A (en) * | 1997-11-21 | 1999-06-29 | Indena S.P.A | Intermediates and methods useful in the semisynthesis of paclitaxel and analogs |
| IT1308636B1 (it) * | 1999-03-02 | 2002-01-09 | Indena Spa | Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii. |
| US6900342B2 (en) * | 2002-05-10 | 2005-05-31 | Dabur India Limited | Anticancer taxanes such as paclitaxel, docetaxel and their structural analogs, and a method for the preparation thereof |
| DK1854799T3 (da) * | 2006-05-12 | 2011-07-18 | Indena Spa | Fremgangsmåde til fremstilling af et taxanderivat |
| WO2016098015A1 (en) * | 2014-12-16 | 2016-06-23 | Khashayar Karimian | New efficient methods for the synthesis of taxane derivatives such as docetaxel and their structural analogous, and a method for the preparation thereof |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5948919A (en) * | 1993-02-05 | 1999-09-07 | Napro Biotherapeutics, Inc. | Paclitaxel synthesis from precursor compounds and methods of producing the same |
| US5475011A (en) * | 1993-03-26 | 1995-12-12 | The Research Foundation Of State University Of New York | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
| FR2706457B1 (fr) * | 1993-06-16 | 1995-07-28 | Rhone Poulenc Rorer Sa | Procédé de préparation d'un acide oxazolidinecarboxylique utile pour préparer des taxoïdes thérapeutiquement actifs. |
| CA2170661A1 (en) * | 1995-03-22 | 1996-09-23 | John K. Thottathil | Novel methods for the preparation of taxanes using oaxzolidine intermediates |
| US5675025A (en) * | 1995-06-07 | 1997-10-07 | Napro Biotherapeutics, Inc. | Paclitaxel synthesis from precursor compounds and methods of producing the same |
| FR2740451B1 (fr) * | 1995-10-27 | 1998-01-16 | Seripharm | Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes |
| KR20000010861A (ko) * | 1996-05-08 | 2000-02-25 | 로렌스 티. 마이젠헬더 | 탁솔의 제조 방법 |
| US5635531A (en) * | 1996-07-08 | 1997-06-03 | Bristol-Myers Squibb Company | 3'-aminocarbonyloxy paclitaxels |
-
1997
- 1997-08-20 KR KR1019970039557A patent/KR100225535B1/ko not_active IP Right Cessation
- 1997-08-21 IL IL12159997A patent/IL121599A/en not_active IP Right Cessation
- 1997-08-25 EP EP97936872A patent/EP0923565B1/de not_active Expired - Lifetime
- 1997-08-25 DK DK97936872T patent/DK0923565T3/da active
- 1997-08-25 ES ES97936872T patent/ES2167777T3/es not_active Expired - Lifetime
- 1997-08-25 WO PCT/KR1997/000157 patent/WO1998008832A1/en active IP Right Grant
- 1997-08-25 PT PT97936872T patent/PT923565E/pt unknown
- 1997-08-25 DE DE69708126T patent/DE69708126T2/de not_active Expired - Lifetime
- 1997-08-25 AU AU39532/97A patent/AU3953297A/en not_active Abandoned
- 1997-08-25 US US09/242,736 patent/US6130336A/en not_active Expired - Fee Related
- 1997-08-25 JP JP51149698A patent/JP3294280B2/ja not_active Expired - Fee Related
- 1997-08-25 ZA ZA9707596A patent/ZA977596B/xx unknown
- 1997-08-25 AT AT97936872T patent/ATE208383T1/de active
- 1997-08-27 AR ARP970103887A patent/AR009349A1/es active IP Right Grant
- 1997-08-27 TR TR97/00863A patent/TR199700863A2/xx unknown
- 1997-08-27 YU YU35997A patent/YU35997A/sh unknown
- 1997-08-27 ID IDP972984A patent/ID19799A/id unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69708126D1 (de) | 2001-12-13 |
| TR199700863A3 (tr) | 1999-10-21 |
| EP0923565B1 (de) | 2001-11-07 |
| WO1998008832A1 (en) | 1998-03-05 |
| ES2167777T3 (es) | 2002-05-16 |
| PT923565E (pt) | 2002-04-29 |
| AR009349A1 (es) | 2000-04-12 |
| IL121599A0 (en) | 1998-02-08 |
| ZA977596B (en) | 1998-04-06 |
| IL121599A (en) | 2004-06-20 |
| EP0923565A1 (de) | 1999-06-23 |
| DK0923565T3 (da) | 2001-12-27 |
| JP2000501425A (ja) | 2000-02-08 |
| TR199700863A2 (xx) | 1999-10-21 |
| KR100225535B1 (ko) | 1999-10-15 |
| JP3294280B2 (ja) | 2002-06-24 |
| ATE208383T1 (de) | 2001-11-15 |
| YU35997A (sh) | 1999-09-27 |
| KR19980018801A (ko) | 1998-06-05 |
| US6130336A (en) | 2000-10-10 |
| AU3953297A (en) | 1998-03-19 |
| ID19799A (id) | 1998-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |