DE69706502D1 - Substituierte 7,12-Dioxabenzo(a)anthracenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen - Google Patents

Substituierte 7,12-Dioxabenzo(a)anthracenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Info

Publication number
DE69706502D1
DE69706502D1 DE69706502T DE69706502T DE69706502D1 DE 69706502 D1 DE69706502 D1 DE 69706502D1 DE 69706502 T DE69706502 T DE 69706502T DE 69706502 T DE69706502 T DE 69706502T DE 69706502 D1 DE69706502 D1 DE 69706502D1
Authority
DE
Germany
Prior art keywords
alkyl
optionally substituted
substituted
anthracene derivatives
dioxabenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69706502T
Other languages
English (en)
Other versions
DE69706502T2 (de
Inventor
Gerard Coudert
Siham Khatib
Pascale Moreau
Daniel-Henri Caignard
Pierre Renard
Ghanem Atassi
Alain Pierre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of DE69706502D1 publication Critical patent/DE69706502D1/de
Application granted granted Critical
Publication of DE69706502T2 publication Critical patent/DE69706502T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/24—[b,e]-condensed with two six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69706502T 1996-11-08 1997-11-06 Substituierte 7,12-Dioxabenzo(a)anthracenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen Expired - Fee Related DE69706502T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9613653A FR2755691B1 (fr) 1996-11-08 1996-11-08 Nouveaux derives 7,12-dioxa-benzo[a]anthraceniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (2)

Publication Number Publication Date
DE69706502D1 true DE69706502D1 (de) 2001-10-11
DE69706502T2 DE69706502T2 (de) 2002-05-08

Family

ID=9497458

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69706502T Expired - Fee Related DE69706502T2 (de) 1996-11-08 1997-11-06 Substituierte 7,12-Dioxabenzo(a)anthracenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen

Country Status (20)

Country Link
US (1) US5807882A (de)
EP (1) EP0841337B1 (de)
JP (1) JPH10139779A (de)
CN (1) CN1096462C (de)
AT (1) ATE205212T1 (de)
AU (1) AU716973B2 (de)
BR (1) BR9705448A (de)
CA (1) CA2220995C (de)
DE (1) DE69706502T2 (de)
DK (1) DK0841337T3 (de)
ES (1) ES2163725T3 (de)
FR (1) FR2755691B1 (de)
GR (1) GR3037037T3 (de)
HK (1) HK1010870A1 (de)
HU (1) HU222286B1 (de)
NO (1) NO974985L (de)
NZ (1) NZ329134A (de)
PL (1) PL323033A1 (de)
PT (1) PT841337E (de)
ZA (1) ZA9710059B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2245029A1 (en) 1998-03-13 1999-09-13 University Of British Columbia Granulatimide compounds as g2 checkpoint inhibitors
WO1999047522A1 (en) * 1998-03-13 1999-09-23 The University Of British Columbia Granulatimide derivatives for use in cancer treatment
FR2845994B1 (fr) * 2002-10-18 2006-05-19 Servier Lab Nouveaux derives de benzo[e][1,4]oxazino[3,2-g]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2845997B1 (fr) * 2002-10-18 2004-12-24 Servier Lab Nouveaux derives de[1,4]benzodioxino[2,3-e]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3966289A (en) * 1989-01-23 1990-08-13 Texas A & M University, The Synthesis and application of 1,3,6,8- and 2,4,6,8-substituted dibenzofurans and dibenzo-p-dioxins as antitumorigenic agents

Also Published As

Publication number Publication date
PL323033A1 (en) 1998-05-11
JPH10139779A (ja) 1998-05-26
US5807882A (en) 1998-09-15
HU9701922D0 (en) 1998-01-28
CN1182087A (zh) 1998-05-20
GR3037037T3 (en) 2002-01-31
PT841337E (pt) 2001-12-28
ZA9710059B (en) 1998-05-25
FR2755691A1 (fr) 1998-05-15
ES2163725T3 (es) 2002-02-01
EP0841337A1 (de) 1998-05-13
CA2220995C (fr) 2002-10-08
HUP9701922A2 (hu) 1998-12-28
FR2755691B1 (fr) 1998-12-04
HUP9701922A3 (en) 2000-06-28
HU222286B1 (hu) 2003-05-28
DE69706502T2 (de) 2002-05-08
AU4440497A (en) 1998-05-14
AU716973B2 (en) 2000-03-09
EP0841337B1 (de) 2001-09-05
NO974985L (no) 1998-05-11
BR9705448A (pt) 2000-03-14
CA2220995A1 (fr) 1998-05-08
HK1010870A1 (en) 1999-07-02
NO974985D0 (no) 1997-10-29
DK0841337T3 (da) 2001-11-19
ATE205212T1 (de) 2001-09-15
NZ329134A (en) 1998-03-25
CN1096462C (zh) 2002-12-18

Similar Documents

Publication Publication Date Title
DK172590A (da) Nye aminer og anvendelse og fremstilling deraf
BR9503536A (pt) Composto processo para sua preparação seu uso e composição farmacêutica
FI894061A (fi) Menetelmä lääkeaineina käyttökelpoisten , -disubstituoitujen N-sykloalkyylialkyylibentsyyliamiinien valmistamiseksi ja niiden synteesivälituotteita
CA2251003A1 (fr) Nouveaux composes derives de n-aryl 2-hydroxy alkylamides
DE69106746D1 (de) Imidazo[1,2-c]chinazolinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen.
DE69706502T2 (de) Substituierte 7,12-Dioxabenzo(a)anthracenderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
FI963440A0 (fi) Uudet aminohappojohdannaiset, näiden valmistusmenetelmä ja näitä yhdisteitä sisältävät farmaseuttiset seokset
ES2086528T3 (es) Nuevos compuestos biciclicos sustituidos con amino.
ATE219491T1 (de) Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ZA9710649B (en) Benzopyran compounds, process for preparing them and pharmaceutical compositions containing them.
DE60000125T2 (de) 7-Oxo-2,3,7,14-tetrahydro-1H-benzo[b]pyrano[3,2-h]acridincarboxylatderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE3465297D1 (en) Derivatives of n-(methoxyphenacyl)amine, their therapeutical use and process for their preparation
NO972943D0 (no) 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende disse forbindelsene og deres anvendelse
PT1101756E (pt) Novos compostos de aminopirrolina processo para a sua preparacao e as composicoes farmaceuticas que os contem
DE69800604D1 (de) Aminierte 6,7,8,9-Tetrahydro-cyclopenta[a]naphthalen- und 2,3-dihydro-cyclopenta[e]inden-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
MY111111A (en) Novel (1-phenyl-1-heterocyclyl) methanol and (1-phenyl -1-heterocyclyl) methylamine drrivatives
DE69801535T2 (de) Benzolsulfonylamin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
NO972942D0 (no) 4-amino-2-ureido-pyrimidin-5-karboksylsyreamider, fremgangsmåter for deres fremstilling, legemidler inneholdende disse forbindelsene og deres anvendelse
TH41375A (th) อนุพันธ์ของ n-(2-เบนโซไธอะโซลิล)-1-พิเพอริดีนอีเธนแอมีน, การเตรียมสารเหล่านี้ และการใช้สารเหล่านี้ในการรักษาโรค
DE69805709D1 (de) Bis Pyrido[4,3-B]Carbazolverbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
SE8900685D0 (sv) New compounds
TH17047A (th) อนุพันธ์ของ n-ซับสทิทิวเทด อะซาไบไซโคลเฮพเทน, การเตรียมและการใช้ประโยชน์ของสารเหล่านี้
HUP9701381A2 (hu) Új 7,8-dihidro-8,8-diszubsztituált-9H-1,3-dioxolo-[4,5-h][2,3]-benzodiazepin-származékok, ilyen hatóanyagot tartalmazó gyógyászati készítmény, és eljárás a hatóanyag előállítására
HUP9701380A2 (hu) Új 8-szubsztituált-9H-1,3-dioxolo-[4,5-h][2,3]-benzodiazepin-származékok, ilyen hatóanyagot tartalmazó gyógyászati készítmény, és eljárás a hatóanyag előállítására
CO4770954A1 (es) Procedimiento mejorado para preparar derivados de ciclopentano aromaticos fusionados en el anillo

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: LES LABORATOIRES SERVIER, NEUILLY-SUR-SEINE, FR

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee