DE69702966D1 - Verfahren zur quantitativen bestimmung einer nukleinsäure in einer lösung durch messung der elektrischen leitfähigkeit und vorrichtung dafür - Google Patents

Verfahren zur quantitativen bestimmung einer nukleinsäure in einer lösung durch messung der elektrischen leitfähigkeit und vorrichtung dafür

Info

Publication number
DE69702966D1
DE69702966D1 DE69702966T DE69702966T DE69702966D1 DE 69702966 D1 DE69702966 D1 DE 69702966D1 DE 69702966 T DE69702966 T DE 69702966T DE 69702966 T DE69702966 T DE 69702966T DE 69702966 D1 DE69702966 D1 DE 69702966D1
Authority
DE
Germany
Prior art keywords
nucleic acid
electrical conductivity
solution
property
parameter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69702966T
Other languages
English (en)
Other versions
DE69702966T2 (de
Inventor
Michael Clarkson
David Cobb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Sensors Ltd
Original Assignee
Molecular Sensors Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Molecular Sensors Ltd filed Critical Molecular Sensors Ltd
Application granted granted Critical
Publication of DE69702966D1 publication Critical patent/DE69702966D1/de
Publication of DE69702966T2 publication Critical patent/DE69702966T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/02—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
    • G01N27/026—Dielectric impedance spectroscopy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69702966T 1996-02-29 1997-02-18 Verfahren zur quantitativen bestimmung einer nukleinsäure in einer lösung durch messung der elektrischen leitfähigkeit und vorrichtung dafür Expired - Fee Related DE69702966T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9604292.4A GB9604292D0 (en) 1996-02-29 1996-02-29 Estimation of a nucleic acid
PCT/GB1997/000447 WO1997032039A1 (en) 1996-02-29 1997-02-18 Method for quantitative determination of a nucleic acid in solution by measurement of the electrical conductivity and apparatus therefor

Publications (2)

Publication Number Publication Date
DE69702966D1 true DE69702966D1 (de) 2000-10-05
DE69702966T2 DE69702966T2 (de) 2001-02-01

Family

ID=10789611

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69702966T Expired - Fee Related DE69702966T2 (de) 1996-02-29 1997-02-18 Verfahren zur quantitativen bestimmung einer nukleinsäure in einer lösung durch messung der elektrischen leitfähigkeit und vorrichtung dafür

Country Status (12)

Country Link
US (1) US5783063A (de)
EP (1) EP0883693B1 (de)
JP (1) JP2001505298A (de)
CN (1) CN1212726A (de)
AT (1) ATE195977T1 (de)
AU (1) AU1804397A (de)
CA (1) CA2247416A1 (de)
DE (1) DE69702966T2 (de)
DK (1) DK0883693T3 (de)
ES (1) ES2149571T3 (de)
GB (1) GB9604292D0 (de)
WO (1) WO1997032039A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9717932D0 (en) * 1997-08-22 1997-10-29 Hybaid Ltd Estimation of nucleic acid
DE19960076C2 (de) * 1999-12-13 2002-12-05 November Ag Molekulare Medizin Verfahren und Vorrichtung zum Nachweis und zur Quantifizierung von Biomolekülen
US7309569B2 (en) 1999-12-21 2007-12-18 Ingeneus, Inc. Parallel or antiparallel, homologous or complementary binding of nucleic acids or analogues thereof to form duplex, triplex or quadruplex complexes
US7220541B2 (en) * 2000-01-24 2007-05-22 Ingeneus, Inc. Homogeneous assay of biopolymer binding by means of multiple measurements under varied conditions
US6613524B1 (en) 2000-01-24 2003-09-02 Ingeneus Corporation Amperometric affinity assay and electrically stimulated complexes of nucleic acids
US20030170659A1 (en) * 2000-01-24 2003-09-11 Ingeneus Corporation Electrical treatment of binding media to encourage, discourage and/or study biopolymer binding
US6982147B2 (en) * 2000-01-24 2006-01-03 Ingeneus Corporation Apparatus for assaying biopolymer binding by means of multiple measurements under varied conditions
GB0002859D0 (en) * 2000-02-08 2000-03-29 Molecular Sensing Plc Process for characterising nucleic acids in solution
GB0027992D0 (en) * 2000-11-16 2001-01-03 Molecular Sensing Plc Apparatus and method for diagnostic assays
US6360595B1 (en) * 2001-03-16 2002-03-26 Ethicon Endo-Surgery, Inc. Liquid measuring device and method of using
US20030022150A1 (en) * 2001-07-24 2003-01-30 Sampson Jeffrey R. Methods for detecting a target molecule
US20060269915A1 (en) * 2003-07-02 2006-11-30 Matsushita Electric Industrial Co., Ltd. Pyrophosphate acid detection sensor, method of detection of nucleic acid, and method of discrimination of base type
US7555933B2 (en) * 2006-08-01 2009-07-07 Thermo Fisher Scientific Inc. Method and software for detecting vacuum concentrator ends-of-runs
US9488609B2 (en) * 2014-02-06 2016-11-08 The Boeing Company Determination of anisotropic conduction characteristics

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60260838A (ja) * 1984-06-08 1985-12-24 Koji Ando オイルの品質測定装置
FR2598227B1 (fr) * 1986-04-30 1989-07-28 Bio Merieux Procede de detection et/ou d'identification d'une substance biologique dans un milieu liquide a l'aide de mesures electriques, et dispositif destine a la mise en oeuvre de ce procede
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
GB2248301A (en) * 1990-09-12 1992-04-01 Ici Plc Apparatus and method for the detection of changes in the composition of a material
GB9215733D0 (en) * 1992-07-24 1992-09-09 British Tech Group Method of and apparatus for determining a property of a sample
EP0690983A4 (de) * 1993-03-05 1998-01-28 Univ Wollongong Gepulste elektrochemische feststellung durch elektroden mit elektroaktivem polymer
GB2289338A (en) * 1994-04-12 1995-11-15 Unvala Ltd Alternating current potential drop measurement

Also Published As

Publication number Publication date
CN1212726A (zh) 1999-03-31
JP2001505298A (ja) 2001-04-17
GB9604292D0 (en) 1996-05-01
DK0883693T3 (da) 2000-11-06
ES2149571T3 (es) 2000-11-01
DE69702966T2 (de) 2001-02-01
EP0883693A1 (de) 1998-12-16
AU1804397A (en) 1997-09-16
EP0883693B1 (de) 2000-08-30
CA2247416A1 (en) 1997-09-04
ATE195977T1 (de) 2000-09-15
WO1997032039A1 (en) 1997-09-04
US5783063A (en) 1998-07-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee