DE69624128D1 - Inhibierende und nichtinhibierende antigenbindende polypeptide gegen menschliche p450 enzyme - Google Patents

Inhibierende und nichtinhibierende antigenbindende polypeptide gegen menschliche p450 enzyme

Info

Publication number
DE69624128D1
DE69624128D1 DE69624128T DE69624128T DE69624128D1 DE 69624128 D1 DE69624128 D1 DE 69624128D1 DE 69624128 T DE69624128 T DE 69624128T DE 69624128 T DE69624128 T DE 69624128T DE 69624128 D1 DE69624128 D1 DE 69624128D1
Authority
DE
Germany
Prior art keywords
inhibitant
enzyms
against human
binding polypeptides
inhibiting anti
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69624128T
Other languages
English (en)
Other versions
DE69624128T2 (de
Inventor
V Gelboin
J Gonzalez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States, AS REPRESENTED BY TH
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of DE69624128D1 publication Critical patent/DE69624128D1/de
Application granted granted Critical
Publication of DE69624128T2 publication Critical patent/DE69624128T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69624128T 1995-11-17 1996-11-15 Inhibierende und nichtinhibierende antigenbindende polypeptide gegen menschliche p450 enzyme Expired - Lifetime DE69624128T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US559808 1995-11-17
US08/559,808 US5939530A (en) 1995-11-17 1995-11-17 Inhibitory and non-inhibitory antigen binding polypeptides against human P450 enzymes
PCT/US1996/017781 WO1997019112A1 (en) 1995-11-17 1996-11-15 Inhibitory and non-inhibitory antigen binding polypeptides against human p450 enzymes

Publications (2)

Publication Number Publication Date
DE69624128D1 true DE69624128D1 (de) 2002-11-07
DE69624128T2 DE69624128T2 (de) 2005-03-24

Family

ID=24235111

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69624128T Expired - Lifetime DE69624128T2 (de) 1995-11-17 1996-11-15 Inhibierende und nichtinhibierende antigenbindende polypeptide gegen menschliche p450 enzyme

Country Status (6)

Country Link
US (1) US5939530A (de)
EP (1) EP0861268B1 (de)
AU (1) AU724468B2 (de)
CA (2) CA2629643C (de)
DE (1) DE69624128T2 (de)
WO (1) WO1997019112A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19721113A1 (de) * 1996-05-20 1997-11-27 Sumitomo Chemical Co Diagnosekit
US6323325B1 (en) 1998-07-23 2001-11-27 The United States Of America As Represented By The Department Of Health And Human Services Agents that bind to and inhibit human cytochrome P450 2A6
US6335428B1 (en) 1998-07-23 2002-01-01 The United States Of America As Represented By The Department Of Health And Human Services Agents that bind to and inhibit human cytochrome P450 1A2
US6623960B1 (en) * 1999-02-12 2003-09-23 The United States Of America As Represented By The Department Of Health And Human Services Agents that bind to and inhibit human cytochrome P450 2C8, 2C9, 2C18 and 2C19
US6908738B2 (en) 1999-02-12 2005-06-21 National Institute Of Health Agents that bind to and inhibit human cytochrome P450 2C19
US6924359B1 (en) * 1999-07-01 2005-08-02 Yale University Neovascular-targeted immunoconjugates
DE60042410D1 (de) * 1999-08-05 2009-07-30 Merck & Co Inc Bestimmung humanes Cytochrom P450 3A4 (CYP3A4)
US6489094B2 (en) * 2000-05-31 2002-12-03 Pfizer Inc. Method and device for drug-drug interaction testing sample preparation
US7262018B2 (en) * 2001-09-10 2007-08-28 National Institutes Of Health Agents that bind to and inhibit human cytochrome P450 2C19
US20030219802A1 (en) * 2002-03-08 2003-11-27 The Regents Of The University Of Michigan Diagnosis and treatment of osteosarcoma

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules

Also Published As

Publication number Publication date
US5939530A (en) 1999-08-17
CA2629643A1 (en) 1997-05-29
CA2238014C (en) 2008-08-12
WO1997019112A1 (en) 1997-05-29
AU724468B2 (en) 2000-09-21
CA2629643C (en) 2013-01-08
CA2238014A1 (en) 1997-05-29
AU7670196A (en) 1997-06-11
EP0861268B1 (de) 2002-10-02
EP0861268A1 (de) 1998-09-02
DE69624128T2 (de) 2005-03-24

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Legal Events

Date Code Title Description
8332 No legal effect for de
8327 Change in the person/name/address of the patent owner

Owner name: THE UNITED STATES OF AMERICA, AS REPRESENTED BY TH

8370 Indication related to discontinuation of the patent is to be deleted