DE69621597D1 - Adsorbens für tumornekrosefaktor alpha, methode zur entfernung durch adsorption und adsorptionsvorrichtung unter verwendung des adsorbens - Google Patents

Adsorbens für tumornekrosefaktor alpha, methode zur entfernung durch adsorption und adsorptionsvorrichtung unter verwendung des adsorbens

Info

Publication number
DE69621597D1
DE69621597D1 DE69621597T DE69621597T DE69621597D1 DE 69621597 D1 DE69621597 D1 DE 69621597D1 DE 69621597 T DE69621597 T DE 69621597T DE 69621597 T DE69621597 T DE 69621597T DE 69621597 D1 DE69621597 D1 DE 69621597D1
Authority
DE
Germany
Prior art keywords
adsorption
tumornescrose
adsorbens
adsorbent
removal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69621597T
Other languages
English (en)
Other versions
DE69621597T2 (de
Inventor
Fumiyasu Hirai
Nobutaka Tani
Takashi Asahi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Publication of DE69621597D1 publication Critical patent/DE69621597D1/de
Application granted granted Critical
Publication of DE69621597T2 publication Critical patent/DE69621597T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3204—Inorganic carriers, supports or substrates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
    • B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
    • B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/327—Polymers obtained by reactions involving only carbon to carbon unsaturated bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69621597T 1995-02-16 1996-02-09 Adsorbens für tumornekrosefaktor alpha, methode zur entfernung durch adsorption und adsorptionsvorrichtung unter verwendung des adsorbens Expired - Lifetime DE69621597T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2812995 1995-02-16
PCT/JP1996/000306 WO1996025228A1 (fr) 1995-02-16 1996-02-09 ADSORBANT DU FACTEUR α DE NECROSE TUMORALE, PROCEDE PERMETTANT DE L'ELIMINER PAR ADSORPTION ET DISPOSITIF D'ADSORPTION UTILISANT LEDIT ADSORBANT

Publications (2)

Publication Number Publication Date
DE69621597D1 true DE69621597D1 (de) 2002-07-11
DE69621597T2 DE69621597T2 (de) 2003-01-16

Family

ID=12240179

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69621597T Expired - Lifetime DE69621597T2 (de) 1995-02-16 1996-02-09 Adsorbens für tumornekrosefaktor alpha, methode zur entfernung durch adsorption und adsorptionsvorrichtung unter verwendung des adsorbens

Country Status (5)

Country Link
EP (1) EP0810027B1 (de)
JP (1) JP3901216B2 (de)
CA (1) CA2213079C (de)
DE (1) DE69621597T2 (de)
WO (1) WO1996025228A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1192963A4 (de) * 2000-04-05 2004-08-25 Toray Industries Adsorbentien für proteine der gruppe high mobility protein und säule zum reinigen von körperflüssigkeiten
CN101370536A (zh) 2005-12-13 2009-02-18 埃克塞拉有限责任公司 用于从血液中体外去除病原微生物、炎性细胞或炎性蛋白质的方法
WO2008155683A1 (en) 2007-06-18 2008-12-24 Firmenich Sa Malodor counteracting compositions and method for their use
AU2010326028B2 (en) 2009-12-01 2014-10-02 Exthera Medical Corporation Method for removing cytokines from blood with surface immobilized polysaccharides
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
EP2570184A1 (de) * 2011-09-15 2013-03-20 InstrAction GmbH Sorptionsmittel, welches auf dessen Oberfläche ein aromatischen Ringsystem mit einer anionischen oder entprotonisierbaren Gruppe enthält, zur Reinigung organischer Moleküle
EP2861273B1 (de) 2012-06-13 2017-08-23 ExThera Medical Corporation Verwendung von heparin und kohlenhydraten zur behandlung von krebs
EP3620218A1 (de) 2013-06-24 2020-03-11 ExThera Medical Corporation Blutfiltrationssystem mit mannose beschichtetem substrat
ES2799398T3 (es) 2013-11-08 2020-12-17 Exthera Medical Corp Métodos para diagnosticar enfermedades infecciosas usando medios de adsorción
MX2016013873A (es) 2014-04-24 2017-03-09 Exthera Medical Corp Metodo para eliminar bacterias de la sangre usando alta velocidad de flujo.
ES2821698T3 (es) 2014-09-22 2021-04-27 Exthera Medical Corp Dispositivo de hemoperfusión portable
EP3422943A4 (de) 2016-03-02 2019-10-16 ExThera Medical Corporation Verfahren zur behandlung von arzneimittelintoxikation
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
TWI762833B (zh) * 2019-11-19 2022-05-01 美商英謬免疫股份有限公司 自生物流體中移除免疫抑制劑之系統及方法
JP7159493B2 (ja) * 2019-11-19 2022-10-24 イミューニコム， インコーポレイテッド 生物学的流体から免疫阻害剤を除去するためのシステム及び方法
US20210146029A1 (en) 2019-11-19 2021-05-20 Immunicom, Inc. System and method for removal of immune inhibitors from biological fluids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1327963C (en) * 1987-09-08 1994-03-22 Ryuichi Yokohari Autoantibody adsorbent and apparatus for removing autoantibodies using the same
JPH0622632B2 (ja) * 1987-09-08 1994-03-30 鐘淵化学工業株式会社 吸着体および除去装置
JPH0622633B2 (ja) * 1987-10-30 1994-03-30 鐘淵化学工業株式会社 吸着体およびそれを用いた除去装置
JPH01171638A (ja) * 1987-12-25 1989-07-06 Kanegafuchi Chem Ind Co Ltd 血清アミロイドａ蛋白用吸着体
EP0476721B1 (de) * 1987-11-20 1995-03-01 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Methode zur Entfernung von Serum-Amyloid-Protein
JPH0611333B2 (ja) * 1988-01-14 1994-02-16 鐘淵化学工業株式会社 免疫複合体の吸着体およびそれを用いた免疫複合体の除去装置
DE4331358A1 (de) * 1992-10-12 1994-04-14 Braun Melsungen Ag Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten

Also Published As

Publication number Publication date
EP0810027A1 (de) 1997-12-03
EP0810027B1 (de) 2002-06-05
DE69621597T2 (de) 2003-01-16
EP0810027A4 (de) 1998-08-05
JP3901216B2 (ja) 2007-04-04
WO1996025228A1 (fr) 1996-08-22
CA2213079A1 (en) 1996-08-22
CA2213079C (en) 2004-12-14

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