DE69535274D1 - Verwendung eines menschlichen interleukin-11 rezeptors - Google Patents
Verwendung eines menschlichen interleukin-11 rezeptorsInfo
- Publication number
- DE69535274D1 DE69535274D1 DE69535274T DE69535274T DE69535274D1 DE 69535274 D1 DE69535274 D1 DE 69535274D1 DE 69535274 T DE69535274 T DE 69535274T DE 69535274 T DE69535274 T DE 69535274T DE 69535274 D1 DE69535274 D1 DE 69535274D1
- Authority
- DE
- Germany
- Prior art keywords
- receptor
- human interleukin
- human
- disclosed
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36230494A | 1994-12-22 | 1994-12-22 | |
US362304 | 1994-12-22 | ||
PCT/US1995/015400 WO1996019574A1 (en) | 1994-12-22 | 1995-11-27 | Human interleukin-11 receptor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69535274D1 true DE69535274D1 (de) | 2006-11-30 |
DE69535274T2 DE69535274T2 (de) | 2007-06-06 |
Family
ID=23425547
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69535274T Expired - Fee Related DE69535274T2 (de) | 1994-12-22 | 1995-11-27 | Verwendung eines menschlichen interleukin-11 rezeptors |
Country Status (10)
Country | Link |
---|---|
US (2) | US6528281B1 (de) |
EP (2) | EP0797664B1 (de) |
JP (2) | JPH10511266A (de) |
AT (1) | ATE342970T1 (de) |
AU (1) | AU717928B2 (de) |
CA (1) | CA2208457A1 (de) |
DE (1) | DE69535274T2 (de) |
DK (1) | DK0797664T3 (de) |
ES (1) | ES2275268T3 (de) |
WO (1) | WO1996019574A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3949715B2 (ja) | 1994-09-05 | 2007-07-25 | アムラド・オペレイションズ・プロプライエタリー・リミテッド | 新規ヘモポイエチン受容体 |
CA2237915A1 (en) * | 1998-05-19 | 1999-11-19 | Stephen Shaughnessy | Osteoporosis treatment |
US6953777B2 (en) | 1999-03-11 | 2005-10-11 | Genetics Indtitute LLC | Use of interleukin-11 to prevent immune-mediated cytotoxicity |
US7452964B2 (en) | 2001-09-07 | 2008-11-18 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides against placenta and adipose tissues |
US20040170955A1 (en) * | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
US7420030B2 (en) | 2000-09-08 | 2008-09-02 | The Board Of Regents Of The University Of Texas System | Aminopeptidase A (APA) targeting peptides for the treatment of cancer |
US20050074747A1 (en) * | 2000-09-08 | 2005-04-07 | Wadih Arap | Biopanning and rapid analysis of selective interactive ligands (brasil) |
CA2454357A1 (en) * | 2001-07-18 | 2003-01-30 | Wadih Arap | An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration |
US8507445B2 (en) * | 2001-09-07 | 2013-08-13 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
US20040048243A1 (en) * | 2001-09-07 | 2004-03-11 | Wadih Arap | Methods and compositions for in vitro targeting |
US7671010B2 (en) * | 2002-08-30 | 2010-03-02 | The Board Of Regents Of The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
US6982080B2 (en) | 2002-03-15 | 2006-01-03 | Wyeth | Hydroxyethyl starch—containing polypeptide compositions |
WO2005065418A2 (en) * | 2003-12-31 | 2005-07-21 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy |
EP1598364A1 (de) * | 2004-05-21 | 2005-11-23 | AGIRx Limited | Chimerischer löslicher Hyper IL-11 Rezeptor und dessen Verwendung |
CA2898618A1 (en) * | 2013-02-07 | 2014-08-14 | Csl Limited | Il-11r binding proteins and uses thereof |
JP6959274B2 (ja) * | 2013-02-07 | 2021-11-02 | シーエスエル、リミテッド | Il−11r結合タンパク質及びその使用 |
GB201522186D0 (en) | 2015-12-16 | 2016-01-27 | Singapore Health Services Pte Ltd And Nat University Of Singapore The | Treatment of fibrosis |
GB201621439D0 (en) | 2016-12-16 | 2017-02-01 | Singapore Health Services Pte Ltd And Nat Univ Of Singapore | IL-11Ra Antibodies |
AU2017378111A1 (en) | 2016-12-16 | 2019-06-13 | National University Of Singapore | IL-11 antibodies |
GB201621431D0 (en) * | 2016-12-16 | 2017-02-01 | Singapore Health Services Pte Ltd And Nat Univ Of Singapore The | Decoy cytokine receptor |
MX2021008727A (es) | 2019-01-21 | 2021-11-04 | Singapore Health Serv Pte Ltd | Tratamiento de la hepatotoxicidad. |
US20210038584A1 (en) * | 2019-08-05 | 2021-02-11 | Novocure Gmbh | Increasing Cancer Cells' Sensitivity to Tumor Treating Fields (TTFields) by Inhibiting IL11 Activity |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215895A (en) | 1989-11-22 | 1993-06-01 | Genetics Institute, Inc. | Dna encoding a mammalian cytokine, interleukin-11 |
US5292646A (en) | 1991-02-06 | 1994-03-08 | Genetics Institute, Inc. | Peptide and protein fusions to thioredoxin and thioredoxin-like molecules |
US5270181A (en) | 1991-02-06 | 1993-12-14 | Genetics Institute, Inc. | Peptide and protein fusions to thioredoxin and thioredoxin-like molecules |
JP3949715B2 (ja) * | 1994-09-05 | 2007-07-25 | アムラド・オペレイションズ・プロプライエタリー・リミテッド | 新規ヘモポイエチン受容体 |
-
1995
- 1995-11-27 AU AU44100/96A patent/AU717928B2/en not_active Ceased
- 1995-11-27 EP EP95942913A patent/EP0797664B1/de not_active Expired - Lifetime
- 1995-11-27 ES ES95942913T patent/ES2275268T3/es not_active Expired - Lifetime
- 1995-11-27 DE DE69535274T patent/DE69535274T2/de not_active Expired - Fee Related
- 1995-11-27 WO PCT/US1995/015400 patent/WO1996019574A1/en active IP Right Grant
- 1995-11-27 CA CA002208457A patent/CA2208457A1/en not_active Abandoned
- 1995-11-27 JP JP8519803A patent/JPH10511266A/ja not_active Withdrawn
- 1995-11-27 EP EP04024209A patent/EP1566440A3/de not_active Withdrawn
- 1995-11-27 AT AT95942913T patent/ATE342970T1/de not_active IP Right Cessation
- 1995-11-27 DK DK95942913T patent/DK0797664T3/da active
-
1996
- 1996-06-14 US US08/663,584 patent/US6528281B1/en not_active Expired - Fee Related
-
1997
- 1997-09-15 US US08/929,846 patent/US6350855B1/en not_active Expired - Fee Related
-
2006
- 2006-03-15 JP JP2006071097A patent/JP2006246890A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
DK0797664T3 (da) | 2007-01-22 |
MX9704618A (es) | 1997-09-30 |
EP1566440A2 (de) | 2005-08-24 |
JP2006246890A (ja) | 2006-09-21 |
DE69535274T2 (de) | 2007-06-06 |
EP0797664A1 (de) | 1997-10-01 |
AU717928B2 (en) | 2000-04-06 |
JPH10511266A (ja) | 1998-11-04 |
ES2275268T3 (es) | 2007-06-01 |
AU4410096A (en) | 1996-07-10 |
ATE342970T1 (de) | 2006-11-15 |
US6528281B1 (en) | 2003-03-04 |
EP0797664B1 (de) | 2006-10-18 |
EP1566440A3 (de) | 2005-10-19 |
WO1996019574A1 (en) | 1996-06-27 |
CA2208457A1 (en) | 1996-06-27 |
US6350855B1 (en) | 2002-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |