DE69526855T2 - Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird - Google Patents

Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird

Info

Publication number
DE69526855T2
DE69526855T2 DE69526855T DE69526855T DE69526855T2 DE 69526855 T2 DE69526855 T2 DE 69526855T2 DE 69526855 T DE69526855 T DE 69526855T DE 69526855 T DE69526855 T DE 69526855T DE 69526855 T2 DE69526855 T2 DE 69526855T2
Authority
DE
Germany
Prior art keywords
gene
probe derived
cancer test
cancer
test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526855T
Other languages
English (en)
Other versions
DE69526855D1 (de
Inventor
Abraham Hochberg
Ilana Ariel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Hadasit Medical Research Services and Development Co
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Medical Research Services and Development Co, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Hadasit Medical Research Services and Development Co
Application granted granted Critical
Publication of DE69526855D1 publication Critical patent/DE69526855D1/de
Publication of DE69526855T2 publication Critical patent/DE69526855T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69526855T 1994-03-07 1995-03-06 Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird Expired - Lifetime DE69526855T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10887994A IL108879A (en) 1994-03-07 1994-03-07 Diagnostic assay for malignancies using the H19 gene and kit
PCT/EP1995/000823 WO1995024503A1 (en) 1994-03-07 1995-03-06 Sensitive cancer test

Publications (2)

Publication Number Publication Date
DE69526855D1 DE69526855D1 (de) 2002-07-04
DE69526855T2 true DE69526855T2 (de) 2002-11-28

Family

ID=11065896

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526855T Expired - Lifetime DE69526855T2 (de) 1994-03-07 1995-03-06 Krebstest, in welchem eine vom H19-Gen abgeleitete Sonde verwendet wird

Country Status (7)

Country Link
US (1) US5955273A (de)
EP (1) EP0759092B1 (de)
AU (1) AU1893095A (de)
DE (1) DE69526855T2 (de)
ES (1) ES2177653T3 (de)
IL (1) IL108879A (de)
WO (1) WO1995024503A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2014772A3 (de) * 1996-04-05 2009-05-27 Antonio Giordano Verfahren zur Diagnose und Prognose von Krebs
US7041654B2 (en) 1997-10-03 2006-05-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for inducing tumor-specific cytotoxicity
US6087164A (en) 1997-10-03 2000-07-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods and compositions for inducing tumor-specific cytotoxicity
DE19828624C1 (de) * 1998-06-26 2000-02-24 Deutsches Krebsforsch Modular aufgebaute RNA-Moleküle mit zwei Sequenzbereichstypen
AU2003272367A1 (en) * 2002-09-12 2004-04-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Method for detection of micro-metastasis
US7482156B2 (en) * 2003-10-15 2009-01-27 Cell Genesys, Inc. Hepatocellular carcinoma specific promoter and uses thereof
JP5383186B2 (ja) * 2005-07-07 2014-01-08 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド Ｈ１９をダウンレギュレートする核酸薬剤、及びそれを使用する方法
WO2007034487A1 (en) 2005-09-22 2007-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer
WO2008087641A2 (en) * 2007-01-16 2008-07-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem H19 silencing nucleic acid agents for treating rheumatoid arthritis
WO2008093331A1 (en) * 2007-01-29 2008-08-07 Yissum Research Development Company Of The Hebrew University Of Jerusalem Antibody conjugates for circumventing multi-drug resistance
WO2009053982A1 (en) * 2007-10-25 2009-04-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Constructs containing multiple expression cassettes for cancer therapy
WO2016203476A1 (en) * 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and compositions for diagnosing and treating urothelial cancer
WO2018214249A1 (zh) * 2017-05-22 2018-11-29 立森印迹诊断技术（无锡）有限公司 一种印记基因分级模型及其组成的系统和应用
WO2018218737A1 (zh) * 2017-06-01 2018-12-06 立森印迹诊断技术（无锡）有限公司 一种印记基因在膀胱肿瘤中的分级模型及其组成的系统
WO2019041689A1 (zh) * 2017-08-31 2019-03-07 立森印迹诊断技术（无锡）有限公司 用于结直肠肿瘤的印记基因分级模型及其组成的系统
WO2019105381A1 (zh) * 2017-11-28 2019-06-06 立森印迹诊断技术有限公司 一种用于检测乳腺肿瘤良恶性程度的分级模型及其应用
CN110714075B (zh) * 2018-07-13 2024-05-03 立森印迹诊断技术（无锡）有限公司 一种用于检测肺肿瘤良恶性程度的分级模型及其应用
CN110890128B (zh) * 2018-09-10 2024-02-09 立森印迹诊断技术（无锡）有限公司 一种用于检测皮肤肿瘤良恶性程度的分级模型及其应用
CN111172278B (zh) * 2018-11-12 2024-02-09 立森印迹诊断技术（无锡）有限公司 一种用于检测前列腺肿瘤良恶性程度的分级模型及其应用
WO2020103905A1 (zh) * 2018-11-21 2020-05-28 立森印迹诊断技术有限公司 肺癌预后标志物、肺癌预后分型模型及其应用
CN112301125A (zh) * 2019-07-30 2021-02-02 立森印迹诊断技术（无锡）有限公司 一种肿瘤标志物及其应用

Also Published As

Publication number Publication date
AU1893095A (en) 1995-09-25
DE69526855D1 (de) 2002-07-04
IL108879A (en) 2000-08-31
EP0759092A1 (de) 1997-02-26
ES2177653T3 (es) 2002-12-16
EP0759092B1 (de) 2002-05-29
IL108879A0 (en) 1994-06-24
US5955273A (en) 1999-09-21
WO1995024503A1 (en) 1995-09-14

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