DE69526206D1 - Verwendung von interleukin-12 fuer die verhinderung von transplantat gegen empfaengerkrankheit - Google Patents
Verwendung von interleukin-12 fuer die verhinderung von transplantat gegen empfaengerkrankheitInfo
- Publication number
- DE69526206D1 DE69526206D1 DE69526206T DE69526206T DE69526206D1 DE 69526206 D1 DE69526206 D1 DE 69526206D1 DE 69526206 T DE69526206 T DE 69526206T DE 69526206 T DE69526206 T DE 69526206T DE 69526206 D1 DE69526206 D1 DE 69526206D1
- Authority
- DE
- Germany
- Prior art keywords
- interleukin
- disease
- prevention
- against receiver
- transplant against
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/186,529 US5573764A (en) | 1994-01-21 | 1994-01-21 | Use of interleukin-12 to prevent graft versus host disease |
PCT/US1995/000879 WO1995019786A1 (en) | 1994-01-21 | 1995-01-20 | Use of interleukin-12 to prevent graft versus host disease |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69526206D1 true DE69526206D1 (de) | 2002-05-08 |
DE69526206T2 DE69526206T2 (de) | 2002-11-21 |
Family
ID=22685309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69526206T Expired - Lifetime DE69526206T2 (de) | 1994-01-21 | 1995-01-20 | Verwendung von interleukin-12 fuer die verhinderung von transplantat gegen empfaengerkrankheit |
Country Status (14)
Country | Link |
---|---|
US (2) | US5573764A (de) |
EP (1) | EP0739212B1 (de) |
JP (1) | JP3825043B2 (de) |
AT (1) | ATE215380T1 (de) |
AU (1) | AU698410B2 (de) |
CA (1) | CA2181568C (de) |
DE (1) | DE69526206T2 (de) |
DK (1) | DK0739212T3 (de) |
ES (1) | ES2179096T3 (de) |
IL (1) | IL112373A (de) |
PT (1) | PT739212E (de) |
TW (1) | TW349021B (de) |
WO (1) | WO1995019786A1 (de) |
ZA (1) | ZA95463B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5573764A (en) * | 1994-01-21 | 1996-11-12 | Genetics Institute, Inc. | Use of interleukin-12 to prevent graft versus host disease |
US5674483A (en) * | 1995-01-31 | 1997-10-07 | National Jewish Medical And Research Center | Treatment for diseases involving inflammation |
JP2000510813A (ja) * | 1995-02-06 | 2000-08-22 | ジェネテイックス・インスティテュート・インコーポレイテッド | Il−12用処方 |
AU7482696A (en) * | 1995-11-01 | 1997-05-22 | Genetics Institute Inc. | Methods for administration of il-12 |
WO1998017689A2 (en) * | 1996-10-18 | 1998-04-30 | Valentis Inc. | Il-12 gene expression and delivery systems and uses |
CA2268276A1 (en) * | 1996-10-18 | 1998-04-30 | Jeff Nordstrom | Gene expression and delivery systems and uses |
AU6150498A (en) * | 1997-02-07 | 1998-08-26 | Wistar Institute, The | Methods and compositions for the inhibition of interleukin-12 production |
WO1998051327A1 (fr) * | 1997-05-16 | 1998-11-19 | Toray Industries, Inc. | Agent therapeutique, procede de traitement, agent prophylactique et procede prophylactique destines au traitement de maladies immunologiques chez les chiens et les chats |
EP1516630A3 (de) * | 1997-10-31 | 2006-05-03 | Wyeth | Verwendung von anti-il-12 Antikörpern bei Transplantationsabstossungen |
US6080399A (en) * | 1998-04-23 | 2000-06-27 | Arch Development Corporation | Vaccine adjuvants for immunotherapy of melanoma |
US7115712B1 (en) * | 1999-12-02 | 2006-10-03 | Maxygen, Inc. | Cytokine polypeptides |
US7638496B2 (en) | 2000-02-15 | 2009-12-29 | Valeant Pharmaceuticals North America | Nucleoside analogs with carboxamidine modified monocyclic base |
US20040175827A1 (en) * | 2001-07-02 | 2004-09-09 | Fowler Daniel H. | Methods of generating human cd4+ th2 cells and uses thereof |
WO2003038062A2 (en) * | 2001-10-31 | 2003-05-08 | The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Generation of use of tc1 and tc2 cells |
US20040241153A1 (en) * | 2001-08-31 | 2004-12-02 | Fowler Daniel H. | Methods of generating human cd4+ th1 cells |
US7718196B2 (en) * | 2001-07-02 | 2010-05-18 | The United States Of America, As Represented By The Department Of Health And Human Services | Rapamycin-resistant T cells and therapeutic uses thereof |
DE10248141B4 (de) * | 2002-10-11 | 2007-04-19 | Universitätsklinikum Hamburg-Eppendorf | Nukleinsäuren und deren Verwendung für die Gentherapie |
US7939058B2 (en) | 2003-07-03 | 2011-05-10 | University Of Southern California | Uses of IL-12 in hematopoiesis |
JP2010539993A (ja) * | 2007-10-08 | 2010-12-24 | イントレキソン コーポレーション | 遺伝子操作した樹状細胞および癌の治療のための使用 |
US20100272863A1 (en) * | 2009-04-24 | 2010-10-28 | Griebel Jonathan M | Soft shaped tortillas |
EP2571516B1 (de) | 2010-05-18 | 2017-11-15 | Neumedicines, Inc | Formulierungen enthaltend il-12 zur erhöhung der hematopoese |
WO2012174056A1 (en) | 2011-06-13 | 2012-12-20 | Neumedicines, Inc. | Mitigation of cutaneous injury with il-12 |
WO2013016634A1 (en) | 2011-07-27 | 2013-01-31 | Neumedicines, Inc. | Use of il-12 to generate endogenous erythropoietin |
US11951157B2 (en) | 2011-10-11 | 2024-04-09 | Universitat Zurich | Methods of treating malignant tumour with IL-12 and anti-PD-1 antibody |
WO2013053775A1 (en) * | 2011-10-11 | 2013-04-18 | Universität Zürich Prorektorat Mnw | Combination medicament comprising il-12 and an agent for blockade of t-cell inhibitory molecules for tumour therapy |
US9636381B2 (en) | 2012-01-18 | 2017-05-02 | Neumedicines, Inc. | Methods for radiation protection by administering IL-12 |
WO2013158959A1 (en) * | 2012-04-19 | 2013-10-24 | Tarix Pharmaceuticals Ltd. | Compositions and methods for treatment of graft-versus-host disease |
KR20230004646A (ko) * | 2020-04-17 | 2023-01-06 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 조작된 il-12 및 il-23 폴리펩타이드 및 이의 용도 |
EP4228610A1 (de) * | 2020-10-13 | 2023-08-23 | Kriya Therapeutics, Inc. | Virale vektorkonstrukte zur abgabe von cytokin-codierenden nukleinsäuren und verwendungen davon zur behandlung von krebs |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA931489B (en) * | 1992-03-04 | 1993-10-28 | Schering Corp | Use of interleuken-10 to suppress graft-vs-host disease |
DE4315127A1 (de) * | 1993-05-07 | 1994-11-10 | Behringwerke Ag | Arzneimittel enthaltend die Untereinheit p40 von Interleukin-12 |
US5573764A (en) * | 1994-01-21 | 1996-11-12 | Genetics Institute, Inc. | Use of interleukin-12 to prevent graft versus host disease |
-
1994
- 1994-01-21 US US08/186,529 patent/US5573764A/en not_active Expired - Lifetime
-
1995
- 1995-01-16 TW TW084100334A patent/TW349021B/zh active
- 1995-01-18 IL IL112373A patent/IL112373A/en not_active IP Right Cessation
- 1995-01-20 ES ES95908628T patent/ES2179096T3/es not_active Expired - Lifetime
- 1995-01-20 AT AT95908628T patent/ATE215380T1/de active
- 1995-01-20 AU AU16875/95A patent/AU698410B2/en not_active Ceased
- 1995-01-20 DK DK95908628T patent/DK0739212T3/da active
- 1995-01-20 JP JP51970895A patent/JP3825043B2/ja not_active Expired - Lifetime
- 1995-01-20 EP EP95908628A patent/EP0739212B1/de not_active Expired - Lifetime
- 1995-01-20 DE DE69526206T patent/DE69526206T2/de not_active Expired - Lifetime
- 1995-01-20 CA CA002181568A patent/CA2181568C/en not_active Expired - Lifetime
- 1995-01-20 ZA ZA95463A patent/ZA95463B/xx unknown
- 1995-01-20 WO PCT/US1995/000879 patent/WO1995019786A1/en active IP Right Grant
- 1995-01-20 PT PT95908628T patent/PT739212E/pt unknown
-
1996
- 1996-04-30 US US08/640,386 patent/US5756085A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IL112373A (en) | 2006-08-01 |
JP3825043B2 (ja) | 2006-09-20 |
CA2181568A1 (en) | 1995-07-27 |
EP0739212A1 (de) | 1996-10-30 |
AU698410B2 (en) | 1998-10-29 |
EP0739212B1 (de) | 2002-04-03 |
ZA95463B (en) | 1995-09-27 |
WO1995019786A1 (en) | 1995-07-27 |
DE69526206T2 (de) | 2002-11-21 |
DK0739212T3 (da) | 2002-06-03 |
CA2181568C (en) | 2007-09-18 |
IL112373A0 (en) | 1995-03-30 |
TW349021B (en) | 1999-01-01 |
US5573764A (en) | 1996-11-12 |
ATE215380T1 (de) | 2002-04-15 |
AU1687595A (en) | 1995-08-08 |
PT739212E (pt) | 2002-08-30 |
ES2179096T3 (es) | 2003-01-16 |
US5756085A (en) | 1998-05-26 |
JPH09508371A (ja) | 1997-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: GENETICS INSTITUTE,LLC(N.D.GES.D.STAATES DELAWARE) Owner name: THE GENERAL HOSPITAL CORP., BOSTON, MASS., US |