DE69521857D1 - Verfahren zur herstellung von optisch aktiven 2-aryl-3-acyloxy-1,2-propandiolen - Google Patents
Verfahren zur herstellung von optisch aktiven 2-aryl-3-acyloxy-1,2-propandiolenInfo
- Publication number
- DE69521857D1 DE69521857D1 DE69521857T DE69521857T DE69521857D1 DE 69521857 D1 DE69521857 D1 DE 69521857D1 DE 69521857 T DE69521857 T DE 69521857T DE 69521857 T DE69521857 T DE 69521857T DE 69521857 D1 DE69521857 D1 DE 69521857D1
- Authority
- DE
- Germany
- Prior art keywords
- propandioles
- acyloxy
- aryl
- optically active
- producing optically
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/26—Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/40—Halogenated unsaturated alcohols
- C07C33/46—Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/28—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with dihydroxylic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
- C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
- C07C69/30—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with trihydroxylic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/63—Halogen-containing esters of saturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/14—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
- C12P7/20—Glycerol
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8074294 | 1994-04-19 | ||
JP8074194 | 1994-04-19 | ||
PCT/JP1995/000749 WO1995028374A1 (fr) | 1994-04-19 | 1995-04-17 | Procede de production de derive de triazole |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69521857D1 true DE69521857D1 (de) | 2001-08-30 |
DE69521857T2 DE69521857T2 (de) | 2002-01-17 |
Family
ID=26421713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69521857T Expired - Fee Related DE69521857T2 (de) | 1994-04-19 | 1995-04-17 | Verfahren zur herstellung von optisch aktiven 2-aryl-3-acyloxy-1,2-propandiolen |
Country Status (8)
Country | Link |
---|---|
US (3) | US5654472A (de) |
EP (2) | EP1120397A3 (de) |
JP (1) | JP3828147B2 (de) |
KR (1) | KR960703103A (de) |
CN (2) | CN1126987A (de) |
DE (1) | DE69521857T2 (de) |
ES (1) | ES2158944T3 (de) |
WO (1) | WO1995028374A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4639606B2 (ja) * | 2003-03-06 | 2011-02-23 | 住友化学株式会社 | プロピレンオキサイドの製造方法 |
CN102952017A (zh) * | 2011-08-24 | 2013-03-06 | 湖北保乐制药有限公司 | 2-乙酰氯基甲氧基-1.3-二氯丙烷的制备方法 |
CN114394944B (zh) * | 2021-12-16 | 2023-06-09 | 南方科技大学 | 一种合成三氮唑抗真菌剂中间体的方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB472392A (en) * | 1936-02-17 | 1937-09-17 | Walter Leigh | Improvements in or connected with bomb sights for flying machines |
US3988446A (en) * | 1974-11-07 | 1976-10-26 | Abbott Laboratories | Glycerides with anti-inflammatory properties |
US4178299A (en) * | 1978-03-27 | 1979-12-11 | Abbott Laboratories | Process for preparing 1,3-diacyl glycerols |
IL59407A (en) * | 1979-03-06 | 1983-12-30 | Sanofi Sa | Di-n-propylacetic acid diesters of glycerol,their preparation and pharmaceutical compositions containing them |
DE3313647A1 (de) * | 1983-04-15 | 1984-10-18 | Barbara Dr. 6220 Rüdesheim Schöbel | Verfahren zur bestimmung von pankreas-lipase |
CH664150A5 (de) * | 1985-01-15 | 1988-02-15 | Peter Paul Prof Dr Speiser | Fumarsaeureprodrug, verfahren zu seiner herstellung und dieses enthaltende darreichungsformen. |
US4931399A (en) * | 1985-09-09 | 1990-06-05 | The Wisconsin Alumni Research Foundation | Process for preparing optically-active glycerol ketal derivatives |
EP0365519B1 (de) * | 1987-06-12 | 1993-03-10 | Molecular Design International, Inc. | Topische vorstufen von arzneimitteln zur behandlung von akne und hautkrankheiten |
US4921798A (en) * | 1989-09-25 | 1990-05-01 | Eastman Kodak Company | Synthesis of (aryl or arylalkyl)-3-hydroxy propionic acids and aryl alkanediols having high optical purity |
TW211006B (de) * | 1990-08-24 | 1993-08-11 | Mochida Pharm Co Ltd | |
JPH05186372A (ja) * | 1991-07-18 | 1993-07-27 | Green Cross Corp:The | 脂肪乳剤及びmri診断用造影剤 |
IL103558A0 (en) * | 1991-10-30 | 1993-03-15 | Schering Corp | Tri-substituted tetrahydrofuran antifungals |
-
1995
- 1995-04-17 ES ES95915335T patent/ES2158944T3/es not_active Expired - Lifetime
- 1995-04-17 EP EP01100108A patent/EP1120397A3/de not_active Withdrawn
- 1995-04-17 EP EP95915335A patent/EP0704419B1/de not_active Expired - Lifetime
- 1995-04-17 WO PCT/JP1995/000749 patent/WO1995028374A1/ja active IP Right Grant
- 1995-04-17 DE DE69521857T patent/DE69521857T2/de not_active Expired - Fee Related
- 1995-04-17 US US08/553,558 patent/US5654472A/en not_active Expired - Fee Related
- 1995-04-17 JP JP52686995A patent/JP3828147B2/ja not_active Expired - Fee Related
- 1995-04-17 CN CN95190316A patent/CN1126987A/zh active Pending
- 1995-04-17 KR KR1019950705763A patent/KR960703103A/ko not_active Application Discontinuation
-
1997
- 1997-03-11 US US08/815,440 patent/US5840553A/en not_active Expired - Fee Related
-
1998
- 1998-08-31 US US09/143,653 patent/US6046354A/en not_active Expired - Fee Related
-
2000
- 2000-11-10 CN CN00130933A patent/CN1322707A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN1322707A (zh) | 2001-11-21 |
CN1126987A (zh) | 1996-07-17 |
KR960703103A (ko) | 1996-06-19 |
DE69521857T2 (de) | 2002-01-17 |
WO1995028374A1 (fr) | 1995-10-26 |
EP1120397A3 (de) | 2003-12-03 |
US5840553A (en) | 1998-11-24 |
EP0704419A4 (de) | 1996-10-30 |
EP1120397A2 (de) | 2001-08-01 |
US6046354A (en) | 2000-04-04 |
EP0704419A1 (de) | 1996-04-03 |
US5654472A (en) | 1997-08-05 |
JP3828147B2 (ja) | 2006-10-04 |
EP0704419B1 (de) | 2001-07-25 |
ES2158944T3 (es) | 2001-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |