DE69424475D1 - Verfahren zur Herstellung von 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluormethyluracil Derivaten - Google Patents
Verfahren zur Herstellung von 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluormethyluracil DerivatenInfo
- Publication number
- DE69424475D1 DE69424475D1 DE69424475T DE69424475T DE69424475D1 DE 69424475 D1 DE69424475 D1 DE 69424475D1 DE 69424475 T DE69424475 T DE 69424475T DE 69424475 T DE69424475 T DE 69424475T DE 69424475 D1 DE69424475 D1 DE 69424475D1
- Authority
- DE
- Germany
- Prior art keywords
- erythropentofuranosyl
- deoxy
- beta
- preparation
- trifluoromethyluracil
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5179415A JP2809972B2 (ja) | 1993-07-20 | 1993-07-20 | ５−トリフルオロメチルウラシルの製造法 |
| JP17941693 | 1993-07-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69424475D1 true DE69424475D1 (de) | 2000-06-21 |
| DE69424475T2 DE69424475T2 (de) | 2001-01-18 |
Family
ID=26499274
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69431537T Expired - Fee Related DE69431537T2 (de) | 1993-07-20 | 1994-07-20 | Verfahren zur Herstellung von 5-Trifluormethyluracil-Derivaten |
| DE69424475T Expired - Fee Related DE69424475T2 (de) | 1993-07-20 | 1994-07-20 | Verfahren zur Herstellung von 1-(2'-deoxy-beta-D-erythropentofuranosyl)-5-trifluormethyluracil Derivaten |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69431537T Expired - Fee Related DE69431537T2 (de) | 1993-07-20 | 1994-07-20 | Verfahren zur Herstellung von 5-Trifluormethyluracil-Derivaten |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US5532349A (de) |
| EP (2) | EP0635517B1 (de) |
| DE (2) | DE69431537T2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2769911B1 (fr) * | 1997-08-07 | 2001-05-25 | F Tech Inc | Procede pour preparer des derives de 5-perfluoroalkyluracile |
| US6423852B1 (en) * | 2000-02-10 | 2002-07-23 | Mitsui Chemicals, Inc. | Process for the preparation of trifluorothymidine derivatives |
| DK1632490T3 (da) * | 2001-06-15 | 2008-01-28 | Shire Biochem Inc | Stereoselektiv fremgangsmåde til fremstillingen af nukleosidanaloger |
| CN106220699A (zh) * | 2016-07-21 | 2016-12-14 | 嘉实（湖南）医药科技有限公司 | 高纯度曲氟尿苷的制备方法 |
| CN106831606B (zh) * | 2017-01-20 | 2019-02-22 | 湖南有色郴州氟化学有限公司 | 一种5-三氟甲基-5,6-二氢尿嘧啶的制备方法 |
| CN109666001B (zh) * | 2019-02-16 | 2022-06-17 | 安徽华胜医药科技有限公司 | 一种多步法制备Elagolix中间体的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU452961A3 (ru) * | 1969-04-11 | 1974-12-05 | Шеринг Аг. (Фирма) | Способ получени пиримидиннуклеозидов |
| JPS6023397A (ja) * | 1983-07-20 | 1985-02-05 | Teijin Ltd | ３′，５′−ジ置換−２′−デオキシ−５−フルオロウリジン類の製造法 |
| JPH02289595A (ja) * | 1989-02-22 | 1990-11-29 | Yuki Gosei Kogyo Co Ltd | ２’―デオキシ―５―トリフルオロメチル―β―ウリジンの製造方法 |
-
1994
- 1994-07-15 US US08/275,455 patent/US5532349A/en not_active Expired - Fee Related
- 1994-07-20 EP EP94111294A patent/EP0635517B1/de not_active Expired - Lifetime
- 1994-07-20 EP EP99122024A patent/EP0990651B1/de not_active Expired - Lifetime
- 1994-07-20 DE DE69431537T patent/DE69431537T2/de not_active Expired - Fee Related
- 1994-07-20 DE DE69424475T patent/DE69424475T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69431537D1 (de) | 2002-11-14 |
| DE69424475T2 (de) | 2001-01-18 |
| US5532349A (en) | 1996-07-02 |
| EP0635517B1 (de) | 2000-05-17 |
| EP0990651B1 (de) | 2002-10-09 |
| EP0635517A1 (de) | 1995-01-25 |
| DE69431537T2 (de) | 2003-06-12 |
| EP0990651A1 (de) | 2000-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |