DE69424275D1 - Alkalische ophthalmische suspensionen - Google Patents

Alkalische ophthalmische suspensionen

Info

Publication number
DE69424275D1
DE69424275D1 DE69424275T DE69424275T DE69424275D1 DE 69424275 D1 DE69424275 D1 DE 69424275D1 DE 69424275 T DE69424275 T DE 69424275T DE 69424275 T DE69424275 T DE 69424275T DE 69424275 D1 DE69424275 D1 DE 69424275D1
Authority
DE
Germany
Prior art keywords
ophthalmic
weight
carboxyl
eye
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69424275T
Other languages
English (en)
Other versions
DE69424275T2 (de
Inventor
Rajesh Patel
M Bowman
Margarita Vildaver
Raymond Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Inc
Original Assignee
Insite Vision Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Insite Vision Inc filed Critical Insite Vision Inc
Publication of DE69424275D1 publication Critical patent/DE69424275D1/de
Application granted granted Critical
Publication of DE69424275T2 publication Critical patent/DE69424275T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
DE69424275T 1993-02-08 1994-02-07 Alkalische ophthalmische suspensionen Expired - Fee Related DE69424275T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/014,512 US5340572A (en) 1993-02-08 1993-02-08 Alkaline ophthalmic suspensions
PCT/US1994/001330 WO1994017785A1 (en) 1993-02-08 1994-02-07 Alkaline ophthalmic suspensions

Publications (2)

Publication Number Publication Date
DE69424275D1 true DE69424275D1 (de) 2000-06-08
DE69424275T2 DE69424275T2 (de) 2000-08-31

Family

ID=21765921

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69424275T Expired - Fee Related DE69424275T2 (de) 1993-02-08 1994-02-07 Alkalische ophthalmische suspensionen

Country Status (12)

Country Link
US (2) US5340572A (de)
EP (1) EP0682512B1 (de)
JP (1) JPH08506588A (de)
AT (1) ATE192332T1 (de)
AU (1) AU685779B2 (de)
CA (1) CA2155179A1 (de)
DE (1) DE69424275T2 (de)
MY (1) MY110062A (de)
PH (1) PH30473A (de)
TW (1) TW440452B (de)
WO (1) WO1994017785A1 (de)
ZA (1) ZA94809B (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5660851A (en) * 1989-12-26 1997-08-26 Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem Ocular inserts
US5631004A (en) 1993-09-30 1997-05-20 Alcon Laboratories, Inc. Use of sustained release antibiotic compositions in ophthalmic surgical procedures
US5773021A (en) * 1994-03-14 1998-06-30 Vetoquinol S.A. Bioadhesive ophthalmic insert
US6309630B1 (en) * 1994-05-24 2001-10-30 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic suspensions
US5767153A (en) * 1995-06-07 1998-06-16 Insite Vision Incorporated Sustained release emulsions
US5747058A (en) * 1995-06-07 1998-05-05 Southern Biosystems, Inc. High viscosity liquid controlled delivery system
US6413536B1 (en) 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
DE69634277T2 (de) * 1995-06-07 2006-01-05 Southern Biosystems, Inc., Birmingham Kontrolliertes zuführsystem mit einer flüssigkeit von hoher viskosität
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
US5683993A (en) * 1995-06-22 1997-11-04 Ciba Vision Corporation Compositions and methods for stabilizing polymers
WO1997020578A1 (en) * 1995-12-04 1997-06-12 University Of Miami Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance
US5814655A (en) * 1996-11-14 1998-09-29 Insite Vision Incorporated Non-steroidal ophthalmic mixtures
US5888493A (en) * 1996-12-05 1999-03-30 Sawaya; Assad S. Ophthalmic aqueous gel formulation and related methods
CA2273852C (en) * 1996-12-06 2009-09-29 Amgen Inc. Combination therapy using an il-1 inhibitor for treating il-1 mediated diseases
US6265444B1 (en) 1997-05-23 2001-07-24 Insite Vision Incorporated Ophthalmic composition
US20060025328A1 (en) * 1997-05-28 2006-02-02 Burns Patrick J Compositions suitable for controlled release of the hormone GnRH and its analogs
IN186245B (de) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6159458A (en) * 1997-11-04 2000-12-12 Insite Vision Sustained release ophthalmic compositions containing water soluble medicaments
TWI243687B (en) * 1998-04-21 2005-11-21 Teijin Ltd Pharmaceutical composition for application to mucosa
US5993782A (en) * 1998-04-28 1999-11-30 Gardner; Conrad O. Therapeutic method for reversing hyposmia in a human patient
DE69940227D1 (de) * 1998-05-08 2009-02-12 Univ Miami Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea
US6914057B1 (en) 1998-09-28 2005-07-05 The Research Foundation Of State University Of New York Inhibitor of cataract formation
CA2343038A1 (en) * 1998-09-28 2000-04-06 Maria Emanuel Ryan A novel inhibitor of cataract formation
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
US6685958B2 (en) 2001-04-25 2004-02-03 Insite Vision Incorporated Quinolone carboxylic acid compositions and related methods of treatment
US6239113B1 (en) * 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US6699492B2 (en) 1999-03-31 2004-03-02 Insite Vision Incorporated Quinolone carboxylic acid compositions and related methods of treatment
DK1197209T3 (da) * 1999-07-15 2011-04-04 Hisamitsu Pharmaceutical Co Perkutant absorberbare præparater
US6552020B1 (en) 1999-07-30 2003-04-22 Allergan, Inc. Compositions including antibiotics and methods for using same
US6166012A (en) * 1999-07-30 2000-12-26 Allergan Sales, Inc. Antibiotic compositions and method for using same
AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
US7141607B1 (en) 2000-03-10 2006-11-28 Insite Vision Incorporated Methods and compositions for treating and inhibiting retinal neovascularization
KR20040019034A (ko) * 2001-07-06 2004-03-04 수캄포 아게 인터루킨 2 억제제 및 항미생물제를 포함하는 국소 투여용조성물
US20030099294A1 (en) * 2001-11-27 2003-05-29 Limin Wang Picture level adaptive frame/field coding for digital video content
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
US20040023935A1 (en) * 2002-08-02 2004-02-05 Dey, L.P. Inhalation compositions, methods of use thereof, and process for preparation of same
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
EP2959893A1 (de) * 2002-12-13 2015-12-30 DURECT Corporation Orales arzneimittelverabreichungssystem mit hochviskosen flüssigkeitsträgermaterialien
AU2004249137B2 (en) * 2003-06-13 2010-03-11 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
US20050095205A1 (en) * 2003-10-31 2005-05-05 Ramesh Krishnamoorthy Combination of loteprednol etabonate and tobramycin for topical ophthalmic use
CN100551378C (zh) * 2003-11-14 2009-10-21 千寿制药株式会社 包含氨基糖苷类抗生素和溴芬酸的水溶液制剂
US8748402B2 (en) 2004-06-07 2014-06-10 Bausch & Lomb Pharma Holdings Corp. Ophthalmic formulations and uses thereof
US8372814B2 (en) 2004-06-07 2013-02-12 Ista Pharmaceuticals, Inc. Ophthalmic formulations and uses thereof
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
SI2767292T1 (sl) 2004-09-17 2017-01-31 Durect Corporation Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem
JP4927752B2 (ja) 2004-11-18 2012-05-09 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイアプリケーターおよび保持装置
US8057842B2 (en) 2004-11-18 2011-11-15 3M Innovative Properties Company Method of contact coating a microneedle array
KR20130026511A (ko) 2004-11-18 2013-03-13 쓰리엠 이노베이티브 프로퍼티즈 컴파니 로우-프로파일 미세 바늘 어레이 인가 장치
KR101224257B1 (ko) * 2004-11-18 2013-01-18 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 어레이를 코팅하기 위한 마스킹 방법
CN101076409B (zh) 2004-11-18 2011-11-23 3M创新有限公司 接触涂敷微针阵列的方法
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20080021068A1 (en) 2006-07-24 2008-01-24 Akorn, Inc. Aqueous gel formulation and method for inducing topical anesthesia
US20090123527A1 (en) * 2006-07-24 2009-05-14 Akorn, Inc. Method of inducing topical anesthesia and transdermal patch
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
US20080188446A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
US20080188445A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
WO2009025763A2 (en) * 2007-08-16 2009-02-26 Schepens Eye Research Institute Therapeutic compositions for treatment of inflammation of ocular and adnexal tissues
JP2011506318A (ja) * 2007-12-06 2011-03-03 デュレクト コーポレーション 経口医薬製剤
CN102026665A (zh) * 2008-05-19 2011-04-20 爱尔康研究有限公司 含有羧基乙烯基聚合物和聚维酮聚合物的药物组合物
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
US10201548B2 (en) 2009-03-06 2019-02-12 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US10980818B2 (en) 2009-03-06 2021-04-20 Sun Pharma Global Fze Methods for treating ocular inflammatory diseases
US8916171B2 (en) * 2010-04-27 2014-12-23 Topical Sinus Therapeutics, Inc. Topical delivery of viscous medications for the treatment of diseases associated with chronic sinusitis
ES2701405T3 (es) 2010-07-29 2019-02-22 Eleven Biotherapeutics Inc Agonistas y antagonistas del receptor tipo I de IL-1 quimérico
CN107693781B (zh) 2013-03-13 2021-11-09 巴扎德制药公司 用于眼部递送的嵌合细胞因子制剂
JP2016515523A (ja) 2013-03-15 2016-05-30 デュレクト コーポレーション 溶解変動性を低減させるためのレオロジー改質剤を有する組成物
JP2023515918A (ja) 2020-01-13 2023-04-17 デュレクト コーポレーション 不純物が低減された徐放性薬物送達システム及び関連の方法

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2798053A (en) * 1952-09-03 1957-07-02 Goodrich Co B F Carboxylic polymers
US3947573A (en) * 1969-12-01 1976-03-30 Burton, Parsons And Company, Inc. Opthalmic solution
US4192827A (en) * 1974-06-27 1980-03-11 Ciba-Geigy Corporation Water-insoluble hydrophilic copolymers
US4039662A (en) * 1975-12-04 1977-08-02 Alcon Laboratories, Inc. Ophthalmic solution
US4127674A (en) * 1977-03-21 1978-11-28 Allergan Pharmaceuticals, Inc. Method of treatment for glaucoma
US4136250A (en) * 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
JPS6056684B2 (ja) * 1977-11-07 1985-12-11 東興薬品工業株式会社 点眼剤
GB2013084B (en) * 1978-01-25 1982-07-28 Alcon Lab Inc Ophthalmic drug dosage
US4271143A (en) * 1978-01-25 1981-06-02 Alcon Laboratories, Inc. Sustained release ophthalmic drug dosage
US4407792A (en) * 1979-05-09 1983-10-04 Alcon Laboratories, Inc. Sustained release ophthalmic drug dosage
US4230724A (en) * 1979-07-16 1980-10-28 Allergan Pharmaceuticals, Inc. Method of treating vascularization of the eye with Flurbiprofen
IE51421B1 (en) * 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
EP0056420A1 (de) * 1981-01-15 1982-07-28 Schering Corporation Ophthalmisches Gel
US4407791A (en) * 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
US4443432A (en) * 1981-10-05 1984-04-17 Alcon Laboratories, Inc. Ophthmalic irrigating solution
US4461904A (en) * 1981-11-20 1984-07-24 Alcon Laboratories, Inc. 2-(Trisubstituted phenylimino)-imidazolines
CA1201066A (en) * 1981-11-20 1986-02-25 Alcon Laboratories, Inc. N-¬3,5-dichloro-4-(2-imidazolidinylideneamino)- phenyl|-acetamide solutions for lowering intraocular pressure
US4644007A (en) * 1981-11-20 1987-02-17 Alcon Laboratories, Inc. 3-chloro-4-(4,5-dihydro-1H-imidazo-2-yl)-amino-5-alkylbenzoic acids, esters, salts, compositions and methods
GR78151B (de) * 1982-04-05 1984-09-26 Alcon Lab Inc
US4559343A (en) * 1982-09-07 1985-12-17 Alcon Laboratories, Inc. Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents
US4478818A (en) * 1982-12-27 1984-10-23 Alza Corporation Ocular preparation housing steroid in two different therapeutic forms
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
WO1984004680A1 (en) * 1983-05-25 1984-12-06 Alcon Lab Inc Ophthalmic gel
EP0145710A1 (de) * 1983-05-25 1985-06-26 Alcon Laboratories, Inc. Ophthalmische lösung
US4528990A (en) * 1983-06-27 1985-07-16 Knowles Wayne C Apparatus for measuring head and spine movement
US4548990A (en) * 1983-08-15 1985-10-22 Ciba-Geigy Corporation Crosslinked, porous polymers for controlled drug delivery
EP0501523B1 (de) * 1983-11-14 1997-04-09 Columbia Laboratories, Inc. Bioadhäsive Mittel
US4524063A (en) * 1983-12-22 1985-06-18 Allergan Pharmaceuticals, Inc. Ophthalmic compositions
US4717725A (en) * 1984-04-11 1988-01-05 Alcon Laboratories, Inc. Ophthalmic wound healing with aldose reductase inhibitors
US4911920A (en) * 1986-07-30 1990-03-27 Alcon Laboratories, Inc. Sustained release, comfort formulation for glaucoma therapy
US4617186A (en) * 1984-12-28 1986-10-14 Alcon Laboratories, Inc. Sustained release drug delivery system utilizing bioadhesive polymers
AU600915B2 (en) * 1985-09-25 1990-08-30 Alcon Laboratories, Inc. Fast response tubeless vacuum aspiration collection cassette
US4686214A (en) * 1985-10-30 1987-08-11 Alcon Laboratories, Inc. Anti-inflammatory compounds for ophthalmic use
IL80298A (en) * 1986-10-14 1993-01-31 Res & Dev Co Ltd Eye drops
US4822819A (en) * 1986-11-07 1989-04-18 Alcon Laboratories, Inc. Use of trimoprostil and derivatives in glaucoma therapy
US4737492A (en) * 1986-12-31 1988-04-12 Alcon Laboratories, Inc. Sparingly soluble salts of cefamandole, and ophthalmic compositions containing same
US4820737A (en) * 1987-02-17 1989-04-11 University Of Iowa Research Foundation Lacrimal secretion stimulant (lss)
GB2203039B (en) * 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
US5188826A (en) * 1988-02-08 1993-02-23 Insite Vision Incorporated Topical ophthalmic suspensions
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
EP0386960A3 (de) * 1989-03-07 1991-10-23 American Cyanamid Company Pharmazeutische Zusammensetzungen zur Verwendung als Wirkstoffabgabevehikel und/oder als Wundverband
FR2653018A1 (fr) * 1989-10-17 1991-04-19 Merck Sharp & Dohme Composition ophtalmique non solide a base de microparticules de polymere contenant au moins un principe actif en suspension dans un milieu dispersant et procede de preparation de ladite composition.
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use

Also Published As

Publication number Publication date
ZA94809B (en) 1994-09-05
PH30473A (en) 1997-05-28
US5340572A (en) 1994-08-23
AU6134694A (en) 1994-08-29
EP0682512A1 (de) 1995-11-22
AU685779B2 (en) 1998-01-29
TW440452B (en) 2001-06-16
MY110062A (en) 1997-12-31
DE69424275T2 (de) 2000-08-31
US5474764A (en) 1995-12-12
CA2155179A1 (en) 1994-08-18
JPH08506588A (ja) 1996-07-16
EP0682512B1 (de) 2000-05-03
WO1994017785A1 (en) 1994-08-18
EP0682512A4 (de) 1996-06-05
ATE192332T1 (de) 2000-05-15

Similar Documents

Publication Publication Date Title
DE69424275D1 (de) Alkalische ophthalmische suspensionen
ZA951323B (en) Liquid ophthalmic sustained release delivery system
ES2012634A6 (es) Un sistema de suministro de un medicamento oftalmico administrable porvia topica y metodo correspondiente.
AU8103991A (en) Ophthalmic suspensions
GR3030381T3 (en) Platelet activating factor antagonists.
BR0307893A (pt) Formulação oftálmica com sistema de goma
IL114193A0 (en) Ophthalmic pharmaceutical compositions
CA2245617A1 (en) Ophthalmic solutions viscosified with tamarind seed polysaccharide
DE69803940D1 (de) Ophthalmische zusammensetzungen mit verlängerte freisetzung enthaltend im wasser lösliche arzneistoffe
ES2161874T3 (es) Composicion oftalmica con viscosidad reducida.
AU5884996A (en) Sustained release ophthalmic emulsions
AU5980200A (en) Ophthalmic compositions in form of aqueous gels
SI1128809T1 (en) Aqueous ophthalmic formulations comprising chitosan
SE9403905D0 (sv) New formulations

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee