DE69424215D1 - Verfahren zur Herstellung von 1-(1,2,4-Triazol-1-yl)-propan-2-ol-Derivaten - Google Patents

Verfahren zur Herstellung von 1-(1,2,4-Triazol-1-yl)-propan-2-ol-Derivaten

Info

Publication number
DE69424215D1
DE69424215D1 DE69424215T DE69424215T DE69424215D1 DE 69424215 D1 DE69424215 D1 DE 69424215D1 DE 69424215 T DE69424215 T DE 69424215T DE 69424215 T DE69424215 T DE 69424215T DE 69424215 D1 DE69424215 D1 DE 69424215D1
Authority
DE
Germany
Prior art keywords
chem
formula
triazol
propan
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69424215T
Other languages
English (en)
Other versions
DE69424215T2 (de
Inventor
Alexander Veinberg
Alexander Senderichin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of DE69424215D1 publication Critical patent/DE69424215D1/de
Publication of DE69424215T2 publication Critical patent/DE69424215T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE69424215T 1993-03-29 1994-03-23 Verfahren zur Herstellung von 1-(1,2,4-Triazol-1-yl)-propan-2-ol-Derivaten Expired - Fee Related DE69424215T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL105200A IL105200A (en) 1993-03-29 1993-03-29 Regiospecific processes for the preparation of 1, 3-bis (1, 2, 4-triazol-1-yl)-propan- 2-ol derivatives

Publications (2)

Publication Number Publication Date
DE69424215D1 true DE69424215D1 (de) 2000-06-08
DE69424215T2 DE69424215T2 (de) 2000-11-30

Family

ID=11064666

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69424215T Expired - Fee Related DE69424215T2 (de) 1993-03-29 1994-03-23 Verfahren zur Herstellung von 1-(1,2,4-Triazol-1-yl)-propan-2-ol-Derivaten

Country Status (15)

Country Link
US (1) US5484936A (de)
EP (1) EP0618198B1 (de)
JP (1) JPH06340637A (de)
KR (1) KR940021536A (de)
AT (1) ATE192440T1 (de)
AU (1) AU683443B2 (de)
CA (1) CA2119995A1 (de)
DE (1) DE69424215T2 (de)
DK (1) DK0618198T3 (de)
ES (1) ES2145097T3 (de)
HU (1) HUT70751A (de)
IL (1) IL105200A (de)
NZ (1) NZ260190A (de)
SK (1) SK281688B6 (de)
ZA (1) ZA942093B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ270418A (en) 1994-02-07 1997-09-22 Eisai Co Ltd Polycyclic triazole & imidazole derivatives, antifungal compositions
CA2139079C (en) * 1994-12-23 1996-05-28 K.S. Keshava Murthy Commercial process for the manufacture of fluconazole and intermediates useful in the manufacture thereof
NZ272586A (en) * 1995-07-17 1996-10-28 Apotex Inc Process for preparing fluconazole and triazolylepoxypropane precursors
WO2004000835A1 (de) * 2002-06-24 2003-12-31 Basf Aktiengesellschaft Verfahren zur herstellung von 1,2,4-triazolylmethyl-oxiranen
GB0900786D0 (en) * 2009-01-19 2009-03-04 Natracine Uk Ltd Therapeutic compositions
BR102013027313B1 (pt) * 2013-10-23 2019-06-18 Iharabras S.A. Indústrias Químicas Processo para a preparação seletiva de (1h-1,2,4-triazol-1-il) alcanóis, composto hidrazinil alcanol obtido por tal processo e seu uso
US11225463B2 (en) * 2016-11-28 2022-01-18 Cellix Bio Private Limited Compositions and methods for the treatment of oral infectious diseases
US20240140916A1 (en) * 2021-02-22 2024-05-02 Kureha Corporation Method for manufacturing azole derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU529930B2 (en) * 1979-03-07 1983-06-23 Zeneca Limited Fungicidal triazole derivatives
NZ208653A (en) * 1980-08-18 1985-09-13 Ici Plc Certain ethylene and 2-halogenoethanols
GB2099818A (en) * 1981-06-06 1982-12-15 Pfizer Ltd Triazoles
DE3262386D1 (en) * 1981-06-06 1985-03-28 Pfizer Ltd Antifungal agents, processes for their preparation, and pharmaceutical compositions containing them
IT1249211B (it) * 1990-06-08 1995-02-20 Ind Chimica Srl Processo per la preparazione di triazolil isopropanoli in particolare fluconazolo

Also Published As

Publication number Publication date
HUT70751A (en) 1995-10-30
US5484936A (en) 1996-01-16
IL105200A0 (en) 1993-07-08
IL105200A (en) 1997-03-18
JPH06340637A (ja) 1994-12-13
KR940021536A (ko) 1994-10-19
EP0618198A1 (de) 1994-10-05
CA2119995A1 (en) 1994-09-30
SK34994A3 (en) 1995-02-08
DE69424215T2 (de) 2000-11-30
NZ260190A (en) 1995-03-28
EP0618198B1 (de) 2000-05-03
SK281688B6 (sk) 2001-06-11
HU9400871D0 (en) 1994-06-28
DK0618198T3 (da) 2000-08-07
ATE192440T1 (de) 2000-05-15
AU5907794A (en) 1994-10-06
AU683443B2 (en) 1997-11-13
ZA942093B (en) 1995-01-13
ES2145097T3 (es) 2000-07-01

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee