DE69421641D1 - Cytochrome P-450 Reduktase Screening für Ergosterol Biosynthese-Inhibitoren - Google Patents

Cytochrome P-450 Reduktase Screening für Ergosterol Biosynthese-Inhibitoren

Info

Publication number
DE69421641D1
DE69421641D1 DE69421641T DE69421641T DE69421641D1 DE 69421641 D1 DE69421641 D1 DE 69421641D1 DE 69421641 T DE69421641 T DE 69421641T DE 69421641 T DE69421641 T DE 69421641T DE 69421641 D1 DE69421641 D1 DE 69421641D1
Authority
DE
Germany
Prior art keywords
cytochrome
reductase
culture
preferred embodiments
test samples
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69421641T
Other languages
English (en)
Other versions
DE69421641T2 (de
Inventor
Donald R Kirsch
Margaret Hsien-Fen Kuh Lai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DE69421641D1 publication Critical patent/DE69421641D1/de
Application granted granted Critical
Publication of DE69421641T2 publication Critical patent/DE69421641T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69421641T 1993-05-25 1994-05-19 Cytochrome P-450 Reduktase Screening für Ergosterol Biosynthese-Inhibitoren Expired - Fee Related DE69421641T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6689393A 1993-05-25 1993-05-25

Publications (2)

Publication Number Publication Date
DE69421641D1 true DE69421641D1 (de) 1999-12-23
DE69421641T2 DE69421641T2 (de) 2000-03-02

Family

ID=22072383

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69421641T Expired - Fee Related DE69421641T2 (de) 1993-05-25 1994-05-19 Cytochrome P-450 Reduktase Screening für Ergosterol Biosynthese-Inhibitoren

Country Status (5)

Country Link
US (1) US6387647B1 (de)
EP (1) EP0626453B1 (de)
AT (1) ATE186747T1 (de)
DE (1) DE69421641T2 (de)
ES (1) ES2139034T3 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995006132A2 (en) * 1993-08-27 1995-03-02 Myco Pharmaceuticals, Incorporated Identifying biologically active agents through culture color change
GB9514184D0 (en) 1995-07-12 1995-09-13 Zeneca Ltd Assay
EP0972847A3 (de) * 1998-04-24 2000-02-09 Hoechst Marion Roussel Verfahren zur Detektion von Antimycotika
JP2002512812A (ja) * 1998-04-24 2002-05-08 ヘキスト・マリオン・ルセル 抗真菌性物質のサッカロミセス・セレビシエ由来の必須遺伝子を用いるスクリーニング法
EP0999284A1 (de) * 1998-09-11 2000-05-10 Hoechst Marion Roussel Verfahren zum Screening auf Antimykotika unter Verwendung essentieller Gene aus C.albicans, sowie die Gene selbst
GB9915399D0 (en) 1999-07-02 1999-09-01 Zeneca Ltd Method
WO2002004660A2 (en) * 2000-07-12 2002-01-17 Wyeth Method for testing for inhibition of drug-metabolizing cytochrome p450 isozymes
AU2002365070A1 (en) * 2001-08-03 2003-06-30 Diversa Corporation P450 enzymes, nucleic acids encoding them and methods of making and using them
DE10230224A1 (de) * 2002-07-04 2004-04-01 Axaron Bioscience Ag Verfahren zur Produktion von S-Adenosyl-L-Methionin durch Fermentation von genetisch modifizierten Mikroorganismen
GB0216203D0 (en) * 2002-07-12 2002-08-21 Imp Cancer Res Tech Mondulation of cytochrome P450 reductase activity
US7700822B2 (en) * 2002-07-12 2010-04-20 Cancer Research Technology Limited Modulation of cytochrome P450 reductase activity

Also Published As

Publication number Publication date
EP0626453A1 (de) 1994-11-30
EP0626453B1 (de) 1999-11-17
ES2139034T3 (es) 2000-02-01
DE69421641T2 (de) 2000-03-02
ATE186747T1 (de) 1999-12-15
US6387647B1 (en) 2002-05-14

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: WYETH HOLDINGS CORP., MADISON, N.J., US

8339 Ceased/non-payment of the annual fee