DE69418252T2 - Stabilisierte, feste pharmazeutische Zubereitung, die Dextromethorphan Phenylpropanolamine und Coffein enthält - Google Patents
Stabilisierte, feste pharmazeutische Zubereitung, die Dextromethorphan Phenylpropanolamine und Coffein enthältInfo
- Publication number
- DE69418252T2 DE69418252T2 DE69418252T DE69418252T DE69418252T2 DE 69418252 T2 DE69418252 T2 DE 69418252T2 DE 69418252 T DE69418252 T DE 69418252T DE 69418252 T DE69418252 T DE 69418252T DE 69418252 T2 DE69418252 T2 DE 69418252T2
- Authority
- DE
- Germany
- Prior art keywords
- pharmaceutical preparation
- caffeine
- stabilized
- solid pharmaceutical
- active ingredients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16115893 | 1993-06-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69418252D1 DE69418252D1 (de) | 1999-06-10 |
DE69418252T2 true DE69418252T2 (de) | 1999-11-04 |
Family
ID=15729701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69418252T Expired - Fee Related DE69418252T2 (de) | 1993-06-30 | 1994-06-29 | Stabilisierte, feste pharmazeutische Zubereitung, die Dextromethorphan Phenylpropanolamine und Coffein enthält |
Country Status (7)
Country | Link |
---|---|
US (2) | US5629316A (de) |
EP (1) | EP0631782B1 (de) |
AT (1) | ATE179602T1 (de) |
AU (1) | AU676315B2 (de) |
CA (1) | CA2127085A1 (de) |
DE (1) | DE69418252T2 (de) |
ZA (1) | ZA944732B (de) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5641512A (en) * | 1995-03-29 | 1997-06-24 | The Procter & Gamble Company | Soft gelatin capsule compositions |
US6274592B1 (en) | 1997-02-04 | 2001-08-14 | Senju Pharmaceutical Co., Ltd. | Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid |
US6110502A (en) * | 1998-02-19 | 2000-08-29 | Mcneil-Ppc, Inc. | Method for producing water dispersible sterol formulations |
RS49890B (sr) * | 1998-07-08 | 2008-08-07 | Kirin-Amgen Inc., | Preparat u formi praška koji sadrži medicinsko sredstvo velike molekulske težine za primenu preko sluzokože |
US6027728A (en) * | 1998-08-05 | 2000-02-22 | Yuen; Liu | Herbal skin regeneration composition and method |
US6242001B1 (en) | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
US6428809B1 (en) * | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
US6841544B2 (en) * | 2000-02-23 | 2005-01-11 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
US6793942B2 (en) | 2000-02-23 | 2004-09-21 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
US6787164B2 (en) | 2000-02-23 | 2004-09-07 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
US6759062B2 (en) | 2000-02-23 | 2004-07-06 | Bioselect Innovations, Inc. | Composition and method for treating the effects of diseases and maladies |
US20070087048A1 (en) * | 2001-05-31 | 2007-04-19 | Abrams Andrew L | Oral dosage combination pharmaceutical packaging |
JP2003252749A (ja) * | 2002-03-04 | 2003-09-10 | Shin Etsu Chem Co Ltd | 外用基剤 |
JPWO2004037293A1 (ja) * | 2002-10-22 | 2006-02-23 | 大日本住友製薬株式会社 | 安定化組成物 |
WO2006024018A2 (en) * | 2004-08-24 | 2006-03-02 | Neuromolecular Pharmaceuticals, Inc. | Compositions for treating nociceptive pain |
US7619007B2 (en) | 2004-11-23 | 2009-11-17 | Adamas Pharmaceuticals, Inc. | Method and composition for administering an NMDA receptor antagonist to a subject |
KR101406456B1 (ko) * | 2005-04-06 | 2014-06-20 | 아다마스 파마슈티칼스, 인코포레이티드 | Cns 장애의 치료를 위한 방법 및 조성물 |
CN101282717B (zh) * | 2005-08-10 | 2012-07-04 | 盐野义制药株式会社 | 苦味抑制制剂 |
US8637078B2 (en) * | 2005-11-24 | 2014-01-28 | Boehringer Ingelheim International Gmbh | Bilayer tablet comprising telmisartan and diuretic |
JP2010503664A (ja) | 2006-09-15 | 2010-02-04 | エコ・ファーマシューティカルズ・ビー.ブイ. | 水不溶性医薬活性物質の舌下、頬若しくは経口投与のための医薬投薬単位 |
CA2664311C (en) * | 2006-09-15 | 2015-08-18 | Echo Pharmaceuticals B.V. | Granulate containing a pharmaceutically active substance and method for its manufacture |
GB2447898B (en) * | 2007-03-24 | 2011-08-17 | Reckitt Benckiser Healthcare | A tablet having improved stability with at least two actives |
US20090087483A1 (en) * | 2007-09-27 | 2009-04-02 | Sison Raymundo A | Oral dosage combination pharmaceutical packaging |
US8439033B2 (en) | 2007-10-09 | 2013-05-14 | Microdose Therapeutx, Inc. | Inhalation device |
CN105381524A (zh) | 2010-01-05 | 2016-03-09 | 微剂量治疗技术公司 | 吸入设备和方法 |
WO2013070656A1 (en) * | 2011-11-07 | 2013-05-16 | Navinta Llc | Sustained release suspension preparation for dextromethorphan |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4049803A (en) * | 1976-04-26 | 1977-09-20 | Bristol-Myers Company | Augmentation of blood levels of aspirin |
JPS5423132A (en) * | 1977-07-19 | 1979-02-21 | Dai Ichi Seiyaku Co Ltd | Analgesic composition |
JPS56154416A (en) * | 1980-04-30 | 1981-11-30 | Kaken Pharmaceut Co Ltd | Antipyretic analgesic composition |
US4420483A (en) * | 1982-07-22 | 1983-12-13 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same |
FR2544315B1 (fr) * | 1983-04-12 | 1985-07-05 | Adir | Polymethylene imines disubstituees, leurs procedes de preparation, et les compositions pharmaceutiques les renfermant |
US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
EP0530311A1 (de) * | 1990-05-21 | 1993-03-10 | Norwich-Eaton Pharmaceuticals, Inc. | Verwendung von phenylpropanolamin als im oberen respirationstrakt wirkendes die schleimsekretion förderndes mittel |
JPH069382A (ja) * | 1992-04-17 | 1994-01-18 | Takeda Chem Ind Ltd | 安定化された固型製剤およびその製造方法 |
-
1994
- 1994-06-24 AU AU65974/94A patent/AU676315B2/en not_active Ceased
- 1994-06-28 US US08/266,641 patent/US5629316A/en not_active Expired - Fee Related
- 1994-06-29 EP EP94304756A patent/EP0631782B1/de not_active Expired - Lifetime
- 1994-06-29 DE DE69418252T patent/DE69418252T2/de not_active Expired - Fee Related
- 1994-06-29 AT AT94304756T patent/ATE179602T1/de not_active IP Right Cessation
- 1994-06-29 CA CA002127085A patent/CA2127085A1/en not_active Abandoned
- 1994-06-30 ZA ZA944732A patent/ZA944732B/xx unknown
-
1996
- 1996-10-30 US US08/742,179 patent/US5726180A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0631782B1 (de) | 1999-05-06 |
US5726180A (en) | 1998-03-10 |
CA2127085A1 (en) | 1994-12-31 |
US5629316A (en) | 1997-05-13 |
AU676315B2 (en) | 1997-03-06 |
DE69418252D1 (de) | 1999-06-10 |
EP0631782A1 (de) | 1995-01-04 |
AU6597494A (en) | 1995-01-12 |
ATE179602T1 (de) | 1999-05-15 |
ZA944732B (en) | 1995-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP |
|
8339 | Ceased/non-payment of the annual fee |