DE69402484D1 - Verfahren zur Herstellung von Naphthochinonen sowie Zwischenprodukte bei deren Herstellung - Google Patents

Verfahren zur Herstellung von Naphthochinonen sowie Zwischenprodukte bei deren Herstellung

Info

Publication number
DE69402484D1
DE69402484D1 DE69402484T DE69402484T DE69402484D1 DE 69402484 D1 DE69402484 D1 DE 69402484D1 DE 69402484 T DE69402484 T DE 69402484T DE 69402484 T DE69402484 T DE 69402484T DE 69402484 D1 DE69402484 D1 DE 69402484D1
Authority
DE
Germany
Prior art keywords
naphthoquinones
intermediates
manufacture
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69402484T
Other languages
English (en)
Other versions
DE69402484T2 (de
Inventor
Kimio Hamamura
Chiaki Seki
Masayuki Konishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Chemical Co Ltd filed Critical Eisai Chemical Co Ltd
Application granted granted Critical
Publication of DE69402484D1 publication Critical patent/DE69402484D1/de
Publication of DE69402484T2 publication Critical patent/DE69402484T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
    • C07C50/14—Quinones the quinoid structure being part of a condensed ring system containing two rings with unsaturation outside the ring system, e.g. vitamin K1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
    • C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/647—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring
    • C07C49/653—Unsaturated compounds containing a keto groups being part of a ring having unsaturation outside the ring polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69402484T 1993-07-26 1994-07-25 Verfahren zur Herstellung von Naphthochinonen sowie Zwischenprodukte bei deren Herstellung Expired - Lifetime DE69402484T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20255193 1993-07-26
JP34221593 1993-12-15

Publications (2)

Publication Number Publication Date
DE69402484D1 true DE69402484D1 (de) 1997-05-15
DE69402484T2 DE69402484T2 (de) 1997-08-28

Family

ID=26513452

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69402484T Expired - Lifetime DE69402484T2 (de) 1993-07-26 1994-07-25 Verfahren zur Herstellung von Naphthochinonen sowie Zwischenprodukte bei deren Herstellung

Country Status (4)

Country Link
US (2) US5412124A (de)
EP (1) EP0636598B1 (de)
CA (1) CA2117412A1 (de)
DE (1) DE69402484T2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902133D0 (sv) * 1999-06-06 1999-06-06 Amersham Pharm Biotech Ab A method for surface modification, a novel support matrix and the use of the matrix
WO2003013420A2 (en) * 2001-08-03 2003-02-20 Vitak Bv Isoprenyl derivatives and their use in the treatment and prevention of osteoporosis and cardiovascular calcification
US6828347B2 (en) 2002-11-06 2004-12-07 Illinois Institute Of Technology Anti-viral multi-quinone compounds and regiospecific synthesis thereof
DK1871353T3 (da) 2005-04-15 2011-04-04 Einstein Coll Med Vitamin k til forebyggelse eller behandling af hududslæt sekundært til anti-EGFR-terapi
DE102009046131A1 (de) * 2009-10-29 2011-05-05 Henkel Ag & Co. Kgaa Alternative Synthese von 1.1-substituierten Olefinen mit elektronenziehenden Substituenten
CA2883882A1 (en) 2012-09-07 2014-03-13 Edison Pharmaceuticals, Inc. Benzoquinone derivatives for treating oxidative stress disorders
CN108948328B (zh) * 2018-06-04 2021-05-11 东华大学 一种聚1,5-二氨基蒽醌纳米棒的制备方法
CN113135820A (zh) * 2021-04-22 2021-07-20 江苏慈星药业有限公司 一种高效率制备医药级维生素k1及其中间体的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3060165D1 (en) * 1979-03-08 1982-03-11 Hoffmann La Roche Process for the stereospecific preparation of compounds of the vitamin k1- and k2-series, as well as new starting materials for the process
DK172072B1 (da) * 1983-07-28 1997-10-13 Hoffmann La Roche Fremgangsmåde til fremstilling af K-vitaminderivater og ubiquinoner samt forbindelser, som er nyttige til anvendelse ved denne fremgangsmåde

Also Published As

Publication number Publication date
CA2117412A1 (en) 1995-01-27
DE69402484T2 (de) 1997-08-28
US5608092A (en) 1997-03-04
EP0636598A1 (de) 1995-02-01
US5412124A (en) 1995-05-02
EP0636598B1 (de) 1997-04-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: EISAI CO., LTD., TOKIO/TOKYO, JP