DE69331484T2 - N-Acetylglucosaminyl-Transferase, dafür kodierendes Gen, entsprechende Vektoren und transformierte Wirte und Herstellungsverfahren dafür - Google Patents

N-Acetylglucosaminyl-Transferase, dafür kodierendes Gen, entsprechende Vektoren und transformierte Wirte und Herstellungsverfahren dafür

Info

Publication number
DE69331484T2
DE69331484T2 DE69331484T DE69331484T DE69331484T2 DE 69331484 T2 DE69331484 T2 DE 69331484T2 DE 69331484 T DE69331484 T DE 69331484T DE 69331484 T DE69331484 T DE 69331484T DE 69331484 T2 DE69331484 T2 DE 69331484T2
Authority
DE
Germany
Prior art keywords
therefor
gene coding
production processes
corresponding vectors
transformed hosts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331484T
Other languages
English (en)
Other versions
DE69331484D1 (de
Inventor
Naoyuki Taniguchi
Atsushi Nishikawa
Nozomi Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Taniguchi Naoyuki Toyonaka Osaka Jp
Suntory Holdings Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suntory Ltd filed Critical Suntory Ltd
Publication of DE69331484D1 publication Critical patent/DE69331484D1/de
Application granted granted Critical
Publication of DE69331484T2 publication Critical patent/DE69331484T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
DE69331484T 1992-08-24 1993-08-24 N-Acetylglucosaminyl-Transferase, dafür kodierendes Gen, entsprechende Vektoren und transformierte Wirte und Herstellungsverfahren dafür Expired - Lifetime DE69331484T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24595092 1992-08-24
JP23711893A JP3979678B2 (ja) 1992-08-24 1993-08-06 新規糖転移酵素及びそれをコードする遺伝子並びに該酵素の製造方法

Publications (2)

Publication Number Publication Date
DE69331484D1 DE69331484D1 (de) 2002-03-14
DE69331484T2 true DE69331484T2 (de) 2002-08-29

Family

ID=26533055

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331484T Expired - Lifetime DE69331484T2 (de) 1992-08-24 1993-08-24 N-Acetylglucosaminyl-Transferase, dafür kodierendes Gen, entsprechende Vektoren und transformierte Wirte und Herstellungsverfahren dafür

Country Status (6)

Country Link
US (2) US5707846A (de)
EP (1) EP0585109B1 (de)
JP (1) JP3979678B2 (de)
DE (1) DE69331484T2 (de)
DK (1) DK0585109T3 (de)
ES (1) ES2167326T3 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5602003A (en) * 1992-06-29 1997-02-11 University Of Georgia Research Foundation N-acetylglucosaminyltransferase V gene
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US8178090B2 (en) * 1995-06-07 2012-05-15 Danisco A/S Recombinant hexose oxidase
US6897052B1 (en) * 1998-08-07 2005-05-24 Glycodesign Holdings Ltd. N-acetylglycosaminyl transferase genes
US7795210B2 (en) 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US8008252B2 (en) 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
US7696163B2 (en) 2001-10-10 2010-04-13 Novo Nordisk A/S Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
AU2002362185A1 (en) 2002-01-09 2003-07-30 Suntory Limited SUGAR TRANSFERASE GnT-V HAVING ANGIOGENIC EFFECT
CA2483436A1 (en) 2002-04-23 2003-11-06 University Of Georgia Research Foundation, Inc. N-acetylglucosaminyltransferase vb coding sequence, recombinant cells and methods
MXPA04012496A (es) 2002-06-21 2005-09-12 Novo Nordisk Healthcare Ag Glicoformos del factor vii pegilados.
CA2519092C (en) 2003-03-14 2014-08-05 Neose Technologies, Inc. Branched water-soluble polymers and their conjugates
PL1615945T3 (pl) 2003-04-09 2012-03-30 Ratiopharm Gmbh Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami
US7691603B2 (en) 2003-04-09 2010-04-06 Novo Nordisk A/S Intracellular formation of peptide conjugates
BRPI0410164A (pt) 2003-05-09 2006-05-16 Neose Technologies Inc composições e métodos para preparação de mutantes de glicosilação de hormÈnio do crescimento humano
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US7956032B2 (en) 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
KR101439880B1 (ko) 2004-01-08 2014-09-12 라티오팜 게엠베하 펩티드의 오-결합형 글리코실화
EP1771066A2 (de) 2004-07-13 2007-04-11 Neose Technologies, Inc. Remodellierung von verzweigtem peg und klykolysierung von glucagonähnlichem peptide-1 glp-1
EP1799249A2 (de) 2004-09-10 2007-06-27 Neose Technologies, Inc. Glycopegyliertes interferon alpha
WO2006050247A2 (en) 2004-10-29 2006-05-11 Neose Technologies, Inc. Remodeling and glycopegylation of fibroblast growth factor (fgf)
NZ556436A (en) 2005-01-10 2010-11-26 Biogenerix Ag Glycopegylated granulocyte colony stimulating factor
EP2386571B1 (de) 2005-04-08 2016-06-01 ratiopharm GmbH Zusammensetzungen und Verfahren zur Herstellung von Glycosylierungsmutanten eines Proteaseresistenten menschlichen Wachstumshormons
WO2006127910A2 (en) 2005-05-25 2006-11-30 Neose Technologies, Inc. Glycopegylated erythropoietin formulations
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
ES2516694T3 (es) 2006-07-21 2014-10-31 Ratiopharm Gmbh Glicosilación de péptidos a través de secuencias de glicosilación con unión en O
WO2008057683A2 (en) 2006-10-03 2008-05-15 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
BRPI0809670A8 (pt) 2007-04-03 2018-12-18 Biogenerix Ag métodos para aumentar a produção de célula tronco, para aumentar o número de granulócitos em um indivíduo, para prevenir, tratar e aliviar a mielossupressão que resulta de uma terapia contra o câncer, para tratar uma condição em um indivíduo, para tratar neutropenia e trombocitopenia em um mamífero, para expandir células tronco hematopoiéticas em cultura, para aumentar a hematopoiese em um indivíduo, para aumentar o número de célulars progenitoras hematopoiéticas em um indivíduo, e para fornecer enxerto estável da medula óssea, e, forma de dosagem oral.
CN101778859B (zh) 2007-06-12 2014-03-26 诺和诺德公司 改良的用于生产核苷酸糖的方法
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
CN103497246B (zh) 2008-02-27 2016-08-10 诺沃—诺迪斯克有限公司 缀合的因子viii分子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69131925D1 (de) * 1990-02-14 2000-02-24 Univ Michigan Ann Arbor Verfahren und produkte für die synthese von oligosaccharidstrukturen auf glykoproteinen, glykolipiden oder als freie moleküle
AU8941191A (en) * 1990-11-30 1992-06-25 Hsc Research And Development Limited Partnership Cloning of udp-n-acetylglucosamine:alpha-3-d-mannoside beta -1,2-n-acetylglucosaminyltransferase i
US5602003A (en) * 1992-06-29 1997-02-11 University Of Georgia Research Foundation N-acetylglucosaminyltransferase V gene

Also Published As

Publication number Publication date
EP0585109A3 (en) 1994-07-06
JPH06197756A (ja) 1994-07-19
ES2167326T3 (es) 2002-05-16
US5834284A (en) 1998-11-10
DE69331484D1 (de) 2002-03-14
JP3979678B2 (ja) 2007-09-19
EP0585109A2 (de) 1994-03-02
EP0585109B1 (de) 2002-01-23
DK0585109T3 (da) 2002-03-11
US5707846A (en) 1998-01-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SUNTORY HOLDINGS LTD., OSAKA, JP

Owner name: TANIGUCHI, NAOYUKI, TOYONAKA, OSAKA, JP