DE69318920D1 - Ellipticinderivate mit Antitumorwirkung - Google Patents
Ellipticinderivate mit AntitumorwirkungInfo
- Publication number
- DE69318920D1 DE69318920D1 DE69318920T DE69318920T DE69318920D1 DE 69318920 D1 DE69318920 D1 DE 69318920D1 DE 69318920 T DE69318920 T DE 69318920T DE 69318920 T DE69318920 T DE 69318920T DE 69318920 D1 DE69318920 D1 DE 69318920D1
- Authority
- DE
- Germany
- Prior art keywords
- tumor effects
- ellipticine derivatives
- alkyl
- heterocycle
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- CTSPAMFJBXKSOY-UHFFFAOYSA-N ellipticine Chemical class N1=CC=C2C(C)=C(NC=3C4=CC=CC=3)C4=C(C)C2=C1 CTSPAMFJBXKSOY-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9211672A FR2696465B1 (fr) | 1992-10-02 | 1992-10-02 | Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69318920D1 true DE69318920D1 (de) | 1998-07-09 |
| DE69318920T2 DE69318920T2 (de) | 1999-01-21 |
Family
ID=9434061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69318920T Expired - Fee Related DE69318920T2 (de) | 1992-10-02 | 1993-10-01 | Ellipticinderivate mit Antitumorwirkung |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5407940A (de) |
| EP (1) | EP0591058B1 (de) |
| JP (1) | JP2529082B2 (de) |
| AT (1) | ATE166875T1 (de) |
| AU (1) | AU660853B2 (de) |
| CA (1) | CA2107485C (de) |
| CY (1) | CY2140B1 (de) |
| DE (1) | DE69318920T2 (de) |
| DK (1) | DK0591058T3 (de) |
| ES (1) | ES2119874T3 (de) |
| FR (1) | FR2696465B1 (de) |
| GR (1) | GR3027772T3 (de) |
| HK (1) | HK1010051A1 (de) |
| NZ (1) | NZ248841A (de) |
| ZA (1) | ZA937308B (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU666416B2 (en) * | 1993-01-29 | 1996-02-08 | Tanabe Seiyaku Co., Ltd. | Ellipticine derivative and process for preparing the same |
| FR2757859B1 (fr) * | 1996-12-30 | 1999-01-29 | Adir | Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757858B1 (fr) * | 1996-12-30 | 1999-01-29 | Adir | Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2767132B1 (fr) * | 1997-08-06 | 1999-09-10 | Adir | Nouveaux composes de bis pyrido [4,3-b] carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP2002522435A (ja) * | 1998-08-03 | 2002-07-23 | アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ | （１ｈ）−ベンゾ［ｃ］キノリン−３−オン誘導体の合成方法 |
| US6231894B1 (en) | 1999-10-21 | 2001-05-15 | Duke University | Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase |
| US6624317B1 (en) | 2000-09-25 | 2003-09-23 | The University Of North Carolina At Chapel Hill | Taxoid conjugates as antimitotic and antitumor agents |
| US6677450B2 (en) | 2000-10-06 | 2004-01-13 | Bristol-Myers Squibb Company | Topoisomerase inhibitors |
| US6653290B2 (en) * | 2000-10-06 | 2003-11-25 | Bristol-Myers Squibb Company | Tumor proliferation inhibitors |
| US6610727B2 (en) | 2000-10-06 | 2003-08-26 | Bristol-Myers Squibb Company | Anhydro sugar derivatives of indolocarbazoles |
| WO2002060867A2 (en) * | 2001-01-29 | 2002-08-08 | Insight Strategy And Marketing Ltd | Carbazole derivatives and their uses as heparanase inhibitors |
| US6855698B2 (en) | 2001-03-22 | 2005-02-15 | Bristol-Myers Squibb Company | Topoisomerase I selective cytotoxic sugar derivatives of indolopyrrolocarbazoles |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU666416B2 (en) * | 1993-01-29 | 1996-02-08 | Tanabe Seiyaku Co., Ltd. | Ellipticine derivative and process for preparing the same |
-
1992
- 1992-10-02 FR FR9211672A patent/FR2696465B1/fr not_active Expired - Fee Related
-
1993
- 1993-10-01 NZ NZ248841A patent/NZ248841A/en unknown
- 1993-10-01 US US08/130,627 patent/US5407940A/en not_active Expired - Fee Related
- 1993-10-01 ZA ZA937308A patent/ZA937308B/xx unknown
- 1993-10-01 DE DE69318920T patent/DE69318920T2/de not_active Expired - Fee Related
- 1993-10-01 AU AU48727/93A patent/AU660853B2/en not_active Ceased
- 1993-10-01 CA CA002107485A patent/CA2107485C/fr not_active Expired - Fee Related
- 1993-10-01 EP EP93402395A patent/EP0591058B1/de not_active Expired - Lifetime
- 1993-10-01 DK DK93402395T patent/DK0591058T3/da active
- 1993-10-01 AT AT93402395T patent/ATE166875T1/de not_active IP Right Cessation
- 1993-10-01 ES ES93402395T patent/ES2119874T3/es not_active Expired - Lifetime
- 1993-10-01 JP JP5247081A patent/JP2529082B2/ja not_active Expired - Fee Related
-
1994
- 1994-07-21 US US08/278,269 patent/US5498611A/en not_active Expired - Fee Related
-
1998
- 1998-08-28 GR GR980401951T patent/GR3027772T3/el unknown
- 1998-09-16 HK HK98110653A patent/HK1010051A1/xx not_active IP Right Cessation
-
1999
- 1999-11-19 CY CY9900036A patent/CY2140B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK0591058T3 (da) | 1999-03-22 |
| CA2107485A1 (fr) | 1994-04-03 |
| JPH06211852A (ja) | 1994-08-02 |
| ZA937308B (en) | 1994-04-22 |
| DE69318920T2 (de) | 1999-01-21 |
| FR2696465B1 (fr) | 1994-12-23 |
| CA2107485C (fr) | 2001-02-27 |
| NZ248841A (en) | 1995-02-24 |
| AU4872793A (en) | 1994-04-14 |
| GR3027772T3 (en) | 1998-11-30 |
| AU660853B2 (en) | 1995-07-06 |
| ES2119874T3 (es) | 1998-10-16 |
| HK1010051A1 (en) | 1999-06-11 |
| US5407940A (en) | 1995-04-18 |
| EP0591058B1 (de) | 1998-06-03 |
| CY2140B1 (en) | 2002-06-21 |
| US5498611A (en) | 1996-03-12 |
| EP0591058A1 (de) | 1994-04-06 |
| FR2696465A1 (fr) | 1994-04-08 |
| ATE166875T1 (de) | 1998-06-15 |
| JP2529082B2 (ja) | 1996-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR |
|
| 8339 | Ceased/non-payment of the annual fee |