DE69316927D1 - Pharmazeutische zusammensetzungen enthaltend contignasterol-verbindungen - Google Patents

Pharmazeutische zusammensetzungen enthaltend contignasterol-verbindungen

Info

Publication number
DE69316927D1
DE69316927D1 DE69316927T DE69316927T DE69316927D1 DE 69316927 D1 DE69316927 D1 DE 69316927D1 DE 69316927 T DE69316927 T DE 69316927T DE 69316927 T DE69316927 T DE 69316927T DE 69316927 D1 DE69316927 D1 DE 69316927D1
Authority
DE
Germany
Prior art keywords
compounds
pct
hydroxyl
contignasterol
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69316927T
Other languages
English (en)
Other versions
DE69316927T2 (de
Inventor
Raymond J Andersen
Theresa M Allen
David L Burgoyne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
University of British Columbia
Original Assignee
University of Alberta
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta, University of British Columbia filed Critical University of Alberta
Publication of DE69316927D1 publication Critical patent/DE69316927D1/de
Application granted granted Critical
Publication of DE69316927T2 publication Critical patent/DE69316927T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69316927T 1992-12-23 1993-12-21 Pharmazeutische zusammensetzungen enthaltend contignasterol-verbindungen Expired - Fee Related DE69316927T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002086221A CA2086221C (en) 1992-12-23 1992-12-23 Contignasterol, and related 3-alpha hydroxy-6-alpha hydroxy-7-beta hydroxy-15-keto-14-beta steroids useful as anti-inflammatory and anti-thrombosis agent
PCT/CA1993/000558 WO1994014451A1 (en) 1992-12-23 1993-12-21 Pharmaceutical compositions comprising contignasterol compounds

Publications (2)

Publication Number Publication Date
DE69316927D1 true DE69316927D1 (de) 1998-03-12
DE69316927T2 DE69316927T2 (de) 1998-10-22

Family

ID=4150905

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69316927T Expired - Fee Related DE69316927T2 (de) 1992-12-23 1993-12-21 Pharmazeutische zusammensetzungen enthaltend contignasterol-verbindungen

Country Status (11)

Country Link
US (1) US5646138A (de)
EP (1) EP0675721B1 (de)
JP (1) JP3366639B2 (de)
AT (1) ATE162946T1 (de)
AU (1) AU673405B2 (de)
CA (2) CA2086221C (de)
DE (1) DE69316927T2 (de)
DK (1) DK0675721T3 (de)
ES (1) ES2114678T3 (de)
GR (1) GR3026346T3 (de)
WO (1) WO1994014451A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100368425C (zh) * 1996-07-11 2008-02-13 茵弗莱采姆药物有限公司 6，7－氧化的甾族化合物及其用途
US6046185A (en) * 1996-07-11 2000-04-04 Inflazyme Pharmaceuticals Ltd. 6,7-oxygenated steroids and uses related thereto
EP1304333A3 (de) * 1996-07-11 2005-03-09 Inflazyme Pharmaceuticals, Ltd. 6,7-oxygenierte Steroide und deren Verwendung
US20040034216A1 (en) 2000-04-28 2004-02-19 Raymond Jeffrey R. 3-Nitrogen-6,7-dioxygen steroids and uses related thereto

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079239A (en) * 1990-02-16 1992-01-07 Harbor Branch Oceanographic Institution, Inc. Sterol disulfates and methods of use

Also Published As

Publication number Publication date
ES2114678T3 (es) 1998-06-01
DE69316927T2 (de) 1998-10-22
GR3026346T3 (en) 1998-06-30
US5646138A (en) 1997-07-08
ATE162946T1 (de) 1998-02-15
CA2086221A1 (en) 1994-06-24
AU673405B2 (en) 1996-11-07
EP0675721B1 (de) 1998-02-04
CA2086221C (en) 2003-07-15
JPH08504773A (ja) 1996-05-21
CA2152621C (en) 2000-10-31
WO1994014451A1 (en) 1994-07-07
DK0675721T3 (da) 1998-04-06
AU5691394A (en) 1994-07-19
CA2152621A1 (en) 1994-07-07
JP3366639B2 (ja) 2003-01-14
EP0675721A1 (de) 1995-10-11

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee