DE69311453D1 - Verfahren zur Herstellung von Alpha-L-Aspartyl-L-Phenylalaninmethylesterhydrochlorid - Google Patents

Verfahren zur Herstellung von Alpha-L-Aspartyl-L-Phenylalaninmethylesterhydrochlorid

Info

Publication number
DE69311453D1
DE69311453D1 DE69311453T DE69311453T DE69311453D1 DE 69311453 D1 DE69311453 D1 DE 69311453D1 DE 69311453 T DE69311453 T DE 69311453T DE 69311453 T DE69311453 T DE 69311453T DE 69311453 D1 DE69311453 D1 DE 69311453D1
Authority
DE
Germany
Prior art keywords
aspartyl
alpha
preparation
methyl ester
ester hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69311453T
Other languages
English (en)
Other versions
DE69311453T2 (de
Inventor
Kazutaka Nagashima
Satoji Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE69311453D1 publication Critical patent/DE69311453D1/de
Application granted granted Critical
Publication of DE69311453T2 publication Critical patent/DE69311453T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
DE69311453T 1992-06-29 1993-06-29 Verfahren zur Herstellung von Alpha-L-Aspartyl-L-Phenylalaninmethylesterhydrochlorid Expired - Fee Related DE69311453T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17065492 1992-06-29
JP18083792A JP3178092B2 (ja) 1992-06-29 1992-07-08 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル塩酸塩の製造方法

Publications (2)

Publication Number Publication Date
DE69311453D1 true DE69311453D1 (de) 1997-07-17
DE69311453T2 DE69311453T2 (de) 1998-02-05

Family

ID=26493584

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69311453T Expired - Fee Related DE69311453T2 (de) 1992-06-29 1993-06-29 Verfahren zur Herstellung von Alpha-L-Aspartyl-L-Phenylalaninmethylesterhydrochlorid

Country Status (4)

Country Link
US (1) US5371269A (de)
EP (1) EP0581032B1 (de)
JP (1) JP3178092B2 (de)
DE (1) DE69311453T2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6657073B1 (en) 1999-08-18 2003-12-02 Daesang Corporation Crystallization of α-L-aspartyl-L-phenylalanine methyl ester

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
JPS6344594A (ja) * 1986-08-11 1988-02-25 Ajinomoto Co Inc Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フエニルアラニンの分離方法

Also Published As

Publication number Publication date
JPH0673091A (ja) 1994-03-15
JP3178092B2 (ja) 2001-06-18
EP0581032B1 (de) 1997-06-11
US5371269A (en) 1994-12-06
DE69311453T2 (de) 1998-02-05
EP0581032A1 (de) 1994-02-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee