DE69232987T2 - Synthetische peptide spezifisch gegen anti-basisches-myelin-protein aus cerebrospinalflüssigkeit von individuen mit multipler sklerose - Google Patents

Synthetische peptide spezifisch gegen anti-basisches-myelin-protein aus cerebrospinalflüssigkeit von individuen mit multipler sklerose Download PDF

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Publication number
DE69232987T2
DE69232987T2 DE69232987T DE69232987T DE69232987T2 DE 69232987 T2 DE69232987 T2 DE 69232987T2 DE 69232987 T DE69232987 T DE 69232987T DE 69232987 T DE69232987 T DE 69232987T DE 69232987 T2 DE69232987 T2 DE 69232987T2
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DE
Germany
Prior art keywords
mbp
synthetic peptides
protein
multiple sclerosis
residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232987T
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English (en)
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DE69232987D1 (de
Inventor
Kenneth G Warren
Ingrid Catz
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University of Alberta
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University of Alberta
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Publication date
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Publication of DE69232987D1 publication Critical patent/DE69232987D1/de
Publication of DE69232987T2 publication Critical patent/DE69232987T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69232987T 1991-10-22 1992-10-15 Synthetische peptide spezifisch gegen anti-basisches-myelin-protein aus cerebrospinalflüssigkeit von individuen mit multipler sklerose Expired - Lifetime DE69232987T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002053799A CA2053799C (en) 1991-10-22 1991-10-22 Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid
PCT/CA1992/000448 WO1993008212A1 (en) 1991-10-22 1992-10-15 Synthetic peptide specificity of anti-myelin basic protein from multiple sclerosis cerebrospinal fluid

Publications (2)

Publication Number Publication Date
DE69232987D1 DE69232987D1 (de) 2003-05-08
DE69232987T2 true DE69232987T2 (de) 2004-01-29

Family

ID=4148603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232987T Expired - Lifetime DE69232987T2 (de) 1991-10-22 1992-10-15 Synthetische peptide spezifisch gegen anti-basisches-myelin-protein aus cerebrospinalflüssigkeit von individuen mit multipler sklerose

Country Status (12)

Country Link
EP (1) EP0610446B1 (de)
AT (1) ATE236193T1 (de)
AU (1) AU2750092A (de)
CA (1) CA2053799C (de)
DE (1) DE69232987T2 (de)
DK (1) DK0610446T3 (de)
ES (1) ES2196007T3 (de)
FI (1) FI111050B (de)
NO (1) NO310513B1 (de)
NZ (1) NZ244807A (de)
RU (1) RU2121850C1 (de)
WO (1) WO1993008212A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817629A (en) * 1991-10-22 1998-10-06 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
US6252040B1 (en) * 1991-10-22 2001-06-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
SI9520118A (sl) * 1994-10-25 1998-08-31 Immulogic Pharmaceutical Corporation Sestavki in zdravljenje multiple skleroze
US6379670B1 (en) 1994-11-18 2002-04-30 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6329499B1 (en) * 1994-11-18 2001-12-11 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogues of human myelin basic protein
DE69525544T2 (de) * 1994-11-18 2002-08-22 Neurocrine Biosciences Inc Peptidanaloga des menschlichen myelinbasischen proteins mit substitution in position 91 zur behandlung von multipler sklerose
US6251396B1 (en) 1994-11-18 2001-06-26 Neurocrine Biosciences, Inc. Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
AU5360796A (en) * 1995-03-09 1996-10-02 Neurocrine Biosciences, Inc. Peptide analogues of human myelin basic protein useful in treating multiple sclerosis
CA2201841C (en) * 1997-04-04 2010-01-26 The Governors Of The University Of Alberta Peptide specificity of anti-myelin basic protein and the administration of myelin basic protein peptides to multiple sclerosis patients
WO2005009455A1 (fr) * 2003-07-29 2005-02-03 Terentiev Alexandr Alexandrovi Composition de peptides presentant une propriete immunoregulatrice
KR20120103591A (ko) 2009-10-12 2012-09-19 라이프바이오 라보라토리즈 엘엘씨 다발성 경화증 치료용 조성물
US9326773B2 (en) 2012-01-26 2016-05-03 Covidien Lp Surgical device including buttress material
WO2024094562A1 (en) * 2022-11-01 2024-05-10 Universität Zürich Novel mbp peptides and their use in the treatment of multiple sclerosis

Also Published As

Publication number Publication date
NO941415L (de) 1994-06-22
ES2196007T3 (es) 2003-12-16
RU2121850C1 (ru) 1998-11-20
CA2053799C (en) 2002-03-12
AU2750092A (en) 1993-05-21
EP0610446B1 (de) 2003-04-02
ATE236193T1 (de) 2003-04-15
FI941860A (fi) 1994-04-21
FI941860A0 (fi) 1994-04-21
WO1993008212A1 (en) 1993-04-29
DK0610446T3 (da) 2003-07-14
CA2053799A1 (en) 1993-04-23
NO310513B1 (no) 2001-07-16
EP0610446A1 (de) 1994-08-17
RU94027578A (ru) 1996-10-20
FI111050B (fi) 2003-05-30
NZ244807A (en) 1997-08-22
DE69232987D1 (de) 2003-05-08
NO941415D0 (no) 1994-04-19

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