DE69232121T2 - Verwendungen einer proteinkinase von ton und neurofilament pk40 - Google Patents
Verwendungen einer proteinkinase von ton und neurofilament pk40Info
- Publication number
- DE69232121T2 DE69232121T2 DE69232121T DE69232121T DE69232121T2 DE 69232121 T2 DE69232121 T2 DE 69232121T2 DE 69232121 T DE69232121 T DE 69232121T DE 69232121 T DE69232121 T DE 69232121T DE 69232121 T2 DE69232121 T2 DE 69232121T2
- Authority
- DE
- Germany
- Prior art keywords
- kinases
- neurofilament
- clay
- protein kinase
- relating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10345—Special targeting system for viral vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74288091A | 1991-08-09 | 1991-08-09 | |
PCT/US1992/005825 WO1993003148A2 (en) | 1991-08-09 | 1992-07-10 | Tau/neurofilament protein kinases pk40 and pk36 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69232121D1 DE69232121D1 (de) | 2001-11-15 |
DE69232121T2 true DE69232121T2 (de) | 2002-06-20 |
Family
ID=24986618
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69232121T Expired - Fee Related DE69232121T2 (de) | 1991-08-09 | 1992-07-10 | Verwendungen einer proteinkinase von ton und neurofilament pk40 |
DE69233330T Expired - Fee Related DE69233330T2 (de) | 1991-08-09 | 1992-07-10 | Verwendung eines inhibitors der tau/neurofilament proteinkinase pk40 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69233330T Expired - Fee Related DE69233330T2 (de) | 1991-08-09 | 1992-07-10 | Verwendung eines inhibitors der tau/neurofilament proteinkinase pk40 |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP1026237B1 (de) |
JP (1) | JPH06510427A (de) |
AT (2) | ATE206755T1 (de) |
AU (1) | AU675410B2 (de) |
CA (1) | CA2115151C (de) |
DE (2) | DE69232121T2 (de) |
DK (2) | DK1026237T3 (de) |
ES (2) | ES2165358T3 (de) |
WO (1) | WO1993003148A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7408027B1 (en) | 1991-12-06 | 2008-08-05 | Max-Planck-Gesellschaft Zur Forderung Der Wissenchaften | Tools for the diagnosis and treatment of Alzheimer's disease |
EP0911390B1 (de) * | 1991-12-06 | 2009-08-05 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verwendung von Protein-Kinasen zur Diagnose und Behandlung der Alzheimer-Krankheit |
JPH07506969A (ja) * | 1992-05-11 | 1995-08-03 | ルードヴィッヒ・インスティテュート・フォア・キャンサー・リサーチ | レセプタ型チロシンキナーゼ類似の分子 |
US6013646A (en) * | 1998-07-02 | 2000-01-11 | Bayer Corporation | Indolocarbazole derivatives useful for the treatment of neurodegenerative diseases and cancer |
CN1461366A (zh) * | 2000-07-07 | 2003-12-10 | 美利肯公司 | 具有耐久拒水和易去污性的纺织基材及其制法 |
CN101084204B (zh) | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
AR092779A1 (es) * | 2011-10-07 | 2015-05-06 | Ac Immune Sa | Composicon farmaceutica que comprende anticuerpos que se unen a conformeros de proteinas tau |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU643235B2 (en) * | 1989-09-15 | 1993-11-11 | Gensia Pharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
HUT61567A (en) * | 1990-12-07 | 1993-01-28 | Sandoz Ag | Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate |
WO1993003177A1 (en) * | 1991-08-09 | 1993-02-18 | Massachusetts Institute Of Technology | Novel tau/neurofilament protein kinases |
EP0544942A1 (de) * | 1991-12-06 | 1993-06-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Neue Werkzeuge für die Diagnose und die Behandlung der Alzheimer-Krankheit |
-
1992
- 1992-07-10 AT AT92915162T patent/ATE206755T1/de not_active IP Right Cessation
- 1992-07-10 DK DK00104460T patent/DK1026237T3/da active
- 1992-07-10 WO PCT/US1992/005825 patent/WO1993003148A2/en active IP Right Grant
- 1992-07-10 EP EP00104460A patent/EP1026237B1/de not_active Expired - Lifetime
- 1992-07-10 ES ES92915162T patent/ES2165358T3/es not_active Expired - Lifetime
- 1992-07-10 DK DK92915162T patent/DK0667898T3/da active
- 1992-07-10 AU AU23240/92A patent/AU675410B2/en not_active Ceased
- 1992-07-10 JP JP5503575A patent/JPH06510427A/ja active Pending
- 1992-07-10 AT AT00104460T patent/ATE262584T1/de not_active IP Right Cessation
- 1992-07-10 DE DE69232121T patent/DE69232121T2/de not_active Expired - Fee Related
- 1992-07-10 EP EP92915162A patent/EP0667898B1/de not_active Expired - Lifetime
- 1992-07-10 DE DE69233330T patent/DE69233330T2/de not_active Expired - Fee Related
- 1992-07-10 CA CA002115151A patent/CA2115151C/en not_active Expired - Fee Related
- 1992-07-10 ES ES00104460T patent/ES2216745T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH06510427A (ja) | 1994-11-24 |
EP1026237A2 (de) | 2000-08-09 |
CA2115151C (en) | 2005-05-17 |
WO1993003148A3 (en) | 1993-04-01 |
ATE262584T1 (de) | 2004-04-15 |
AU675410B2 (en) | 1997-02-06 |
EP1026237A3 (de) | 2001-03-28 |
DK1026237T3 (da) | 2004-07-19 |
DK0667898T3 (da) | 2002-02-04 |
DE69233330T2 (de) | 2005-03-10 |
EP1026237B1 (de) | 2004-03-24 |
ATE206755T1 (de) | 2001-10-15 |
DE69232121D1 (de) | 2001-11-15 |
EP0667898A1 (de) | 1995-08-23 |
WO1993003148A2 (en) | 1993-02-18 |
EP0667898B1 (de) | 2001-10-10 |
DE69233330D1 (de) | 2004-04-29 |
AU2324092A (en) | 1993-03-02 |
ES2165358T3 (es) | 2002-03-16 |
ES2216745T3 (es) | 2004-11-01 |
CA2115151A1 (en) | 1993-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |