DE69229768T2 - Anti-Tumor Impfstoffe, die Interleukin-6 transfizierte Zellen enthalten - Google Patents

Anti-Tumor Impfstoffe, die Interleukin-6 transfizierte Zellen enthalten

Info

Publication number
DE69229768T2
DE69229768T2 DE69229768T DE69229768T DE69229768T2 DE 69229768 T2 DE69229768 T2 DE 69229768T2 DE 69229768 T DE69229768 T DE 69229768T DE 69229768 T DE69229768 T DE 69229768T DE 69229768 T2 DE69229768 T2 DE 69229768T2
Authority
DE
Germany
Prior art keywords
transfected cells
vaccines containing
tumor vaccines
containing interleukin
tumor vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69229768T
Other languages
English (en)
Other versions
DE69229768D1 (de
Inventor
Lea Eisenbach
Angel Porgador
Michael Feldman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of DE69229768D1 publication Critical patent/DE69229768D1/de
Publication of DE69229768T2 publication Critical patent/DE69229768T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/204—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001136—Cytokines
    • A61K39/00114—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69229768T 1991-10-22 1992-10-20 Anti-Tumor Impfstoffe, die Interleukin-6 transfizierte Zellen enthalten Expired - Fee Related DE69229768T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL9982191A IL99821A (en) 1991-10-22 1991-10-22 Antitumor vaccines comprising cells transfected with a gene encoding human il-6

Publications (2)

Publication Number Publication Date
DE69229768D1 DE69229768D1 (de) 1999-09-16
DE69229768T2 true DE69229768T2 (de) 2000-05-31

Family

ID=11062992

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69229768T Expired - Fee Related DE69229768T2 (de) 1991-10-22 1992-10-20 Anti-Tumor Impfstoffe, die Interleukin-6 transfizierte Zellen enthalten

Country Status (8)

Country Link
EP (1) EP0538952B1 (de)
AT (1) ATE183101T1 (de)
CA (1) CA2081043C (de)
DE (1) DE69229768T2 (de)
DK (1) DK0538952T3 (de)
ES (1) ES2137172T3 (de)
GR (1) GR3031785T3 (de)
IL (1) IL99821A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2109481A1 (en) * 1992-10-29 1994-04-30 Lea Eisenbach Anti-metastatic vaccine
PL190445B1 (pl) * 1995-05-15 2005-12-30 Akademia Medyczna Im K Marcink Genetyczna szczepionka przeciwrakowa
JP2000508884A (ja) 1995-08-18 2000-07-18 スローンケタリング インスティテュート フォー キャンサー リサーチ 癌および感染症の治療方法ならびにそれに有用な組成物
US6761892B1 (en) 1995-08-18 2004-07-13 Sloan-Kettering Institute For Cancer Research Heat shock protein-based vaccines and immunotherapies
US6277368B1 (en) 1996-07-25 2001-08-21 The Regents Of The University Of California Cancer immunotherapy using autologous tumor cells combined with cells expressing a membrane cytokine
US6087174A (en) * 1996-12-26 2000-07-11 Johns Hopkins University, School Of Medicine Growth medium for primary pancreatic tumor cell culture
WO1999004009A1 (en) * 1997-07-14 1999-01-28 Wisconsin Alumni Research Foundation Method of dna vaccination using dna encoding antigen and encoding il6
US7420037B2 (en) 2003-02-13 2008-09-02 Antigenics Inc. Heat shock protein-based vaccines and immunotherapies
US7309491B2 (en) 2003-04-11 2007-12-18 Antigenics Inc. Heat shock protein-based vaccines and immunotherapies

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3922444A1 (de) * 1988-03-01 1991-01-10 Deutsches Krebsforsch Virusmodifizierte tumorvakzine fuer die immuntherapie von tumormetastasen
DK0551401T3 (da) * 1990-09-14 1996-01-22 Univ Texas Fremgangsmåde og præparater til genterapi og potensering af antitumor-immunitet

Also Published As

Publication number Publication date
ATE183101T1 (de) 1999-08-15
EP0538952B1 (de) 1999-08-11
IL99821A0 (en) 1992-08-18
DK0538952T3 (da) 2000-03-13
CA2081043A1 (en) 1993-04-23
GR3031785T3 (en) 2000-02-29
CA2081043C (en) 2006-01-10
IL99821A (en) 1996-07-23
EP0538952A1 (de) 1993-04-28
DE69229768D1 (de) 1999-09-16
ES2137172T3 (es) 1999-12-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee