DE69229281D1 - Synthese von stabilen, wasserlöslichen chemilumineszierenden 1,2-dioxetanen und ihre zwischenprodukte - Google Patents

Synthese von stabilen, wasserlöslichen chemilumineszierenden 1,2-dioxetanen und ihre zwischenprodukte

Info

Publication number
DE69229281D1
DE69229281D1 DE69229281T DE69229281T DE69229281D1 DE 69229281 D1 DE69229281 D1 DE 69229281D1 DE 69229281 T DE69229281 T DE 69229281T DE 69229281 T DE69229281 T DE 69229281T DE 69229281 D1 DE69229281 D1 DE 69229281D1
Authority
DE
Germany
Prior art keywords
dioxetanes
synthesis
stable
water
intermediate products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69229281T
Other languages
English (en)
Other versions
DE69229281T2 (de
Inventor
Irena Bronstein
Brooks Edwards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Tropix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tropix Inc filed Critical Tropix Inc
Publication of DE69229281D1 publication Critical patent/DE69229281D1/de
Application granted granted Critical
Publication of DE69229281T2 publication Critical patent/DE69229281T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6551—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring
    • C07F9/65512—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a four-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69229281T 1992-03-05 1992-03-05 Synthese von stabilen, wasserlöslichen chemilumineszierenden 1,2-dioxetanen und ihre zwischenprodukte Expired - Lifetime DE69229281T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1992/001530 WO1993018022A1 (en) 1992-03-05 1992-03-05 Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor

Publications (2)

Publication Number Publication Date
DE69229281D1 true DE69229281D1 (de) 1999-07-01
DE69229281T2 DE69229281T2 (de) 1999-09-23

Family

ID=22230833

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69229281T Expired - Lifetime DE69229281T2 (de) 1992-03-05 1992-03-05 Synthese von stabilen, wasserlöslichen chemilumineszierenden 1,2-dioxetanen und ihre zwischenprodukte

Country Status (7)

Country Link
EP (1) EP0629195B1 (de)
JP (1) JPH07504434A (de)
AU (1) AU672582B2 (de)
DE (1) DE69229281T2 (de)
DK (1) DK0629195T3 (de)
ES (1) ES2131529T3 (de)
WO (1) WO1993018022A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5777135A (en) * 1995-07-31 1998-07-07 Lumigen, Inc. Di-substituted 1,2-dioxetane compounds having increased water solubility and assay compositions
US5631167A (en) * 1995-07-31 1997-05-20 Bayer Corporation Capsule chemistry analytical methods employing dioxetane chemiluminescence
US6355441B1 (en) * 1998-07-28 2002-03-12 Tropix, Inc. Benzothiazole dioxetanes
US6660529B2 (en) * 1998-07-28 2003-12-09 Pe Corporation Heteroaryl substituted benzothiazole dioxetanes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956477A (en) * 1987-12-31 1990-09-11 Tropix, Inc. Synthesis of 1,2-dioxetanes

Also Published As

Publication number Publication date
WO1993018022A1 (en) 1993-09-16
AU2334292A (en) 1993-10-05
EP0629195A1 (de) 1994-12-21
JPH07504434A (ja) 1995-05-18
ES2131529T3 (es) 1999-08-01
DK0629195T3 (da) 1999-11-08
AU672582B2 (en) 1996-10-10
DE69229281T2 (de) 1999-09-23
EP0629195B1 (de) 1999-05-26
EP0629195A4 (de) 1995-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLERA CORP. (N.D.GES.D.STAATES DELAWARE), BEDFOR

8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

Free format text: PFANDRECHT AUFGEHOBEN