DE69225306T2 - 1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen - Google Patents

1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen

Info

Publication number
DE69225306T2
DE69225306T2 DE69225306T DE69225306T DE69225306T2 DE 69225306 T2 DE69225306 T2 DE 69225306T2 DE 69225306 T DE69225306 T DE 69225306T DE 69225306 T DE69225306 T DE 69225306T DE 69225306 T2 DE69225306 T2 DE 69225306T2
Authority
DE
Germany
Prior art keywords
oleoylazacycloheptanone
biological membranes
medicines containing
enhance transport
oleylazacycloheptan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69225306T
Other languages
English (en)
Other versions
DE69225306D1 (de
Inventor
Henry Ernest Center For Bodde
Johannes Aaltje Bouwstra
Maria Helene Ponec
Ferdinand Spies
Klaus Sandrock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanol Schwarz GmbH
UCB Pharma GmbH
Original Assignee
Sanol Schwarz GmbH
UCB Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanol Schwarz GmbH, UCB Pharma GmbH filed Critical Sanol Schwarz GmbH
Publication of DE69225306D1 publication Critical patent/DE69225306D1/de
Application granted granted Critical
Publication of DE69225306T2 publication Critical patent/DE69225306T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69225306T 1992-01-20 1992-01-20 1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen Expired - Fee Related DE69225306T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92200159A EP0552504B1 (de) 1992-01-20 1992-01-20 1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen
HK98104161A HK1005063A1 (en) 1992-01-20 1998-05-14 Pharmaceutical compositions containing 1- oleylazacycloheptan-2-one as enhancing agent of transport across biological membranes

Publications (2)

Publication Number Publication Date
DE69225306D1 DE69225306D1 (de) 1998-06-04
DE69225306T2 true DE69225306T2 (de) 1998-12-17

Family

ID=26131246

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69225306T Expired - Fee Related DE69225306T2 (de) 1992-01-20 1992-01-20 1-Oleoylazacycloheptanon(2) enthaltende Arzneimittel zur Verstärkung des Transports durch biologische Membranen

Country Status (5)

Country Link
EP (1) EP0552504B1 (de)
AT (1) ATE165597T1 (de)
DE (1) DE69225306T2 (de)
ES (1) ES2114907T3 (de)
HK (1) HK1005063A1 (de)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1343426A (en) * 1971-05-07 1974-01-10 Dow Corning Tld Acylated lactams
US4461638A (en) * 1975-06-19 1984-07-24 Nelson Research & Development Company Delivery of plant nutrients
DE2616993A1 (de) * 1976-04-17 1977-10-27 Bayer Ag Verfahren zum faerben von flaechengebilden
US4310525A (en) * 1981-01-23 1982-01-12 Nelson Research & Development Company Method of treatment of inflammation
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
EP0251425B1 (de) * 1986-04-03 1993-06-16 Hercon Laboratories Corporation Artikel für die Verabreichung pharmakologisch aktiver Substanzen
US4755535A (en) * 1986-04-23 1988-07-05 Nelson Research & Development Co. Compositions comprising 1-substituted azacycloalkenes
ES2038154T3 (es) * 1986-11-19 1993-07-16 Whitby Research, Inc. Un procedimiento para preparar una composicion para potenciar la penetracion de membranas de al menos un agente sistematicamente activo.
US4879275A (en) * 1987-09-30 1989-11-07 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agent
CA1334646C (en) * 1988-04-08 1995-03-07 James Vanolden Peck Transdermal penetration enhancers

Also Published As

Publication number Publication date
ATE165597T1 (de) 1998-05-15
EP0552504A1 (de) 1993-07-28
DE69225306D1 (de) 1998-06-04
ES2114907T3 (es) 1998-06-16
HK1005063A1 (en) 1998-12-18
EP0552504B1 (de) 1998-04-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee