DE69224524T2 - Antimikrobielle breitspektrum-verbindungen und verfahren zu deren verwendung - Google Patents
Antimikrobielle breitspektrum-verbindungen und verfahren zu deren verwendungInfo
- Publication number
- DE69224524T2 DE69224524T2 DE69224524T DE69224524T DE69224524T2 DE 69224524 T2 DE69224524 T2 DE 69224524T2 DE 69224524 T DE69224524 T DE 69224524T DE 69224524 T DE69224524 T DE 69224524T DE 69224524 T2 DE69224524 T2 DE 69224524T2
- Authority
- DE
- Germany
- Prior art keywords
- broad range
- range connections
- tryptophan
- antimicrobial
- microbial growth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/715,271 US5324716A (en) | 1991-06-14 | 1991-06-14 | Broad spectrum antimicrobial compounds and methods of use |
PCT/US1992/004920 WO1992022308A1 (en) | 1991-06-14 | 1992-06-10 | Broad spectrum antimicrobial compounds and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69224524D1 DE69224524D1 (de) | 1998-04-02 |
DE69224524T2 true DE69224524T2 (de) | 1998-07-02 |
Family
ID=24873340
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69224524T Expired - Fee Related DE69224524T2 (de) | 1991-06-14 | 1992-06-10 | Antimikrobielle breitspektrum-verbindungen und verfahren zu deren verwendung |
Country Status (9)
Country | Link |
---|---|
US (1) | US5324716A (de) |
EP (1) | EP0590070B1 (de) |
JP (1) | JPH06510757A (de) |
AT (1) | ATE163429T1 (de) |
CA (1) | CA2111336C (de) |
DE (1) | DE69224524T2 (de) |
DK (1) | DK0590070T3 (de) |
ES (1) | ES2112909T3 (de) |
WO (1) | WO1992022308A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5547939A (en) * | 1991-06-14 | 1996-08-20 | The Regents Of The University Of California | Broad spectrum antimicrobial compounds and methods of use |
US5646119A (en) * | 1991-11-01 | 1997-07-08 | Periodontix, Inc. | D-amino acid histatin-based peptides as anti-fungal and anti-bacterial agents |
US5912230A (en) * | 1991-11-01 | 1999-06-15 | Periodontix, Inc. | Anti-fungal and anti-bacterial histatin-based peptides |
US5631228A (en) * | 1991-11-01 | 1997-05-20 | Periodontix, Inc. | Anti-fungal and anti-bacterial histatin-based peptides |
US5486503A (en) * | 1991-11-01 | 1996-01-23 | The Trustees Of Boston University | Anti-fungal histatin-based peptides |
US5885965A (en) * | 1991-11-01 | 1999-03-23 | Periodontix, Inc. | Anti-fungal D-amino acid histatin-based peptides |
US5830993A (en) * | 1995-04-10 | 1998-11-03 | Kansas State University Research Foundation | Synthetic antimicrobial peptide |
US6713605B1 (en) * | 1996-04-10 | 2004-03-30 | Kansas State University Research Foundation | Synthetic peptides that inhibit leukocyte superoxide anion production and/or attract leukocytes |
JP3860838B2 (ja) * | 1995-08-23 | 2006-12-20 | ユニバーシティー オブ ブリティッシュ コロンビア | 抗微生物性陽イオン性ペプチドおよびそのスクリーニング方法 |
US5994308A (en) * | 1996-02-28 | 1999-11-30 | Board Of Trustees Of Southern Illinois University | Broad spectrum antimicrobial peptides containing a tryptophan triplet and methods of use |
US6180604B1 (en) | 1996-08-21 | 2001-01-30 | Micrologix Biotech Inc. | Compositions and methods for treating infections using analogues of indolicidin |
US6503881B2 (en) * | 1996-08-21 | 2003-01-07 | Micrologix Biotech Inc. | Compositions and methods for treating infections using cationic peptides alone or in combination with antibiotics |
US6531573B1 (en) | 1997-12-18 | 2003-03-11 | Trustees Of Boston University | Antifungal and antibacterial peptides |
US6303575B1 (en) | 1998-05-12 | 2001-10-16 | The Regents Of The University Of California | Indolicidin analogs and methods of using same |
US6444645B1 (en) * | 1998-06-18 | 2002-09-03 | The Regents Of The University Of California | Crosslink-stabilized indolicidin analogs |
US6335318B1 (en) | 1999-05-10 | 2002-01-01 | The Regents Of The University Of California | Antimicrobial theta defensins and methods of using same |
US7550558B2 (en) * | 2001-06-01 | 2009-06-23 | Fundacao De Ampara A Pesquiso Do Estado De Sao Paolo (Fapesp) | Antimicrobial peptides and methods for identifying and using such peptides |
US6835536B2 (en) | 2001-08-21 | 2004-12-28 | Micrologix Biotech Inc. | Antimicrobial cationic peptides and formulations thereof |
CA2457885A1 (en) * | 2001-08-24 | 2003-03-06 | Micrologix Biotech Inc. | Antimicrobial and anti-inflammatory peptides |
US7119070B2 (en) * | 2002-04-30 | 2006-10-10 | The Regents Of The University Of California | Antimicrobial theta defensins, analogs thereof, and methods of use |
US7357956B2 (en) * | 2003-12-03 | 2008-04-15 | Unilever Bestfoods, North America, Division Of Conopco, Inc. | Tea beverage with improved flavor |
US7671028B2 (en) * | 2004-02-04 | 2010-03-02 | Postech Foundation | Peptides that antagonize FPR class receptor mediated signaling |
US20080255052A1 (en) * | 2004-12-23 | 2008-10-16 | The Regents Of The University Of California | Immunologic regulation by theta defensins |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54144367A (en) * | 1978-04-28 | 1979-11-10 | Suntory Ltd | Novel peptide |
US4543252A (en) * | 1982-01-21 | 1985-09-24 | The Regents Of The University Of California | Cationic oligopeptides having microbicidal activity |
JPS6236331A (ja) * | 1985-08-12 | 1987-02-17 | Kenji Suzuki | 抗感染症剤ならびに免疫賦活剤 |
-
1991
- 1991-06-14 US US07/715,271 patent/US5324716A/en not_active Expired - Lifetime
-
1992
- 1992-06-10 JP JP5501014A patent/JPH06510757A/ja active Pending
- 1992-06-10 DE DE69224524T patent/DE69224524T2/de not_active Expired - Fee Related
- 1992-06-10 CA CA002111336A patent/CA2111336C/en not_active Expired - Fee Related
- 1992-06-10 AT AT92914513T patent/ATE163429T1/de not_active IP Right Cessation
- 1992-06-10 DK DK92914513.4T patent/DK0590070T3/da active
- 1992-06-10 ES ES92914513T patent/ES2112909T3/es not_active Expired - Lifetime
- 1992-06-10 EP EP92914513A patent/EP0590070B1/de not_active Expired - Lifetime
- 1992-06-10 WO PCT/US1992/004920 patent/WO1992022308A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO1992022308A1 (en) | 1992-12-23 |
EP0590070B1 (de) | 1998-02-25 |
EP0590070A4 (de) | 1995-05-24 |
ES2112909T3 (es) | 1998-04-16 |
DE69224524D1 (de) | 1998-04-02 |
DK0590070T3 (da) | 1998-03-16 |
ATE163429T1 (de) | 1998-03-15 |
CA2111336C (en) | 1999-10-05 |
EP0590070A1 (de) | 1994-04-06 |
CA2111336A1 (en) | 1992-12-23 |
US5324716A (en) | 1994-06-28 |
JPH06510757A (ja) | 1994-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |