DE69224507D1 - Beta-Oxo-Beta-Benzenepropanthioamidderivate - Google Patents

Beta-Oxo-Beta-Benzenepropanthioamidderivate

Info

Publication number
DE69224507D1
DE69224507D1 DE69224507T DE69224507T DE69224507D1 DE 69224507 D1 DE69224507 D1 DE 69224507D1 DE 69224507 T DE69224507 T DE 69224507T DE 69224507 T DE69224507 T DE 69224507T DE 69224507 D1 DE69224507 D1 DE 69224507D1
Authority
DE
Germany
Prior art keywords
group
beta
hydrogen atom
alkyl
atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69224507T
Other languages
English (en)
Other versions
DE69224507T2 (de
Inventor
Tetsuo Sekiya
Mikio Tsutsui
Tetsuro Shimpuku
Tatsuo Nagano
Junko Hayashi
Asami Seino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Corp filed Critical Mitsubishi Chemical Corp
Publication of DE69224507D1 publication Critical patent/DE69224507D1/de
Application granted granted Critical
Publication of DE69224507T2 publication Critical patent/DE69224507T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/02Monothiocarboxylic acids
    • C07C327/04Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/12Monothiocarboxylic acids having carbon atoms of thiocarboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/38Amides of thiocarboxylic acids
    • C07C327/46Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/38Amides of thiocarboxylic acids
    • C07C327/40Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C327/44Amides of thiocarboxylic acids having carbon atoms of thiocarboxamide groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of an unsaturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
DE69224507T 1991-12-26 1992-12-09 Beta-Oxo-Beta-Benzenepropanthioamidderivate Expired - Fee Related DE69224507T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP34565791 1991-12-26

Publications (2)

Publication Number Publication Date
DE69224507D1 true DE69224507D1 (de) 1998-04-02
DE69224507T2 DE69224507T2 (de) 1998-08-20

Family

ID=18378084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224507T Expired - Fee Related DE69224507T2 (de) 1991-12-26 1992-12-09 Beta-Oxo-Beta-Benzenepropanthioamidderivate

Country Status (11)

Country Link
US (2) US5332833A (de)
EP (1) EP0548680B1 (de)
JP (1) JP2707936B2 (de)
KR (1) KR930012698A (de)
AT (1) ATE163410T1 (de)
CA (1) CA2086210A1 (de)
DE (1) DE69224507T2 (de)
DK (1) DK0548680T3 (de)
ES (1) ES2113399T3 (de)
GR (1) GR3026240T3 (de)
TW (1) TW242138B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0548680B1 (de) * 1991-12-26 1998-02-25 Mitsubishi Chemical Corporation Beta-Oxo-Beta-Benzenepropanthioamidderivate
WO1996022086A1 (fr) * 1995-01-17 1996-07-25 Mitsubishi Chemical Corporation MEDICAMENT CONTENANT UN DERIVE DE β-OXO-β-BENZENEPROPANE-THIOAMIDE
CN1162151C (zh) * 1998-01-14 2004-08-18 日本新药株式会社 钾通道激活剂
BR0208956A (pt) * 2001-04-16 2004-07-13 Tanabe Seiyaku Co Abridor de canais de k ativados por cálcio de grande condutância
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
CA2469435A1 (en) 2001-12-21 2003-07-24 X-Ceptor Therapeutics, Inc. Modulators of lxr
ES2600460T3 (es) 2005-05-10 2017-02-09 Intermune, Inc. Derivados de piridona-2-ona como moduladores del sistema de proteína cinasa activada por estrés
CA2726588C (en) 2008-06-03 2019-04-16 Karl Kossen Compounds and methods for treating inflammatory and fibrotic disorders
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
WO2015153683A1 (en) 2014-04-02 2015-10-08 Intermune, Inc. Anti-fibrotic pyridinones
US10112929B2 (en) 2015-03-09 2018-10-30 Bristol-Myers Squibb Company Lactams as inhibitors of rock
KR102512548B1 (ko) 2017-12-22 2023-03-22 삼성디스플레이 주식회사 유기 전계 발광 소자 및 유기 전계 발광 소자용 함질소 화합물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460909C2 (de) * 1974-12-21 1986-02-27 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von alpha- Oxothiodimethylamiden
JPS5444660A (en) * 1977-08-29 1979-04-09 Yamanouchi Pharmaceut Co Ltd Heterocyclic compound and its preparation
US4299845A (en) * 1980-04-14 1981-11-10 Schering Corporation Dermatological compositions and methods of use therefor
GB8530015D0 (en) * 1985-12-05 1986-01-15 Ici Plc Biologically active amide derivatives
US4851526A (en) * 1987-09-04 1989-07-25 Schering A.G. 1-(4-Substituted phenyl)-1H-imidazoles compounds
US5185375A (en) * 1987-12-18 1993-02-09 May & Baker Limited Thioformamide derivatives
EP0548680B1 (de) * 1991-12-26 1998-02-25 Mitsubishi Chemical Corporation Beta-Oxo-Beta-Benzenepropanthioamidderivate

Also Published As

Publication number Publication date
ATE163410T1 (de) 1998-03-15
DK0548680T3 (da) 1998-09-23
KR930012698A (ko) 1993-07-21
EP0548680B1 (de) 1998-02-25
TW242138B (de) 1995-03-01
JP2707936B2 (ja) 1998-02-04
US5332833A (en) 1994-07-26
JPH05246980A (ja) 1993-09-24
EP0548680A1 (de) 1993-06-30
ES2113399T3 (es) 1998-05-01
GR3026240T3 (en) 1998-05-29
CA2086210A1 (en) 1993-06-27
DE69224507T2 (de) 1998-08-20
US5439927A (en) 1995-08-08

Similar Documents

Publication Publication Date Title
DE3677452D1 (de) Chinazolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
FI892787A (fi) Analogiamenetelmä terapeuttisesti käyttökelpoisten 1-indolyylialkyyli-4-(substituoitu pyridinyyli)piperatsiinien valmistamiseksi
CA2119572A1 (en) Oxygen substituted derivatives of nucleophile-nitric oxide adducts as nitric oxide donor prodrugs
DE69224507D1 (de) Beta-Oxo-Beta-Benzenepropanthioamidderivate
DE69120100D1 (de) Annelierte Thiophen-Derivate, ihre Herstellung und Verwendung
FI943142A (fi) Amidi- ja ureajohdannaiset, joilla on veren korkeita kolesteroliarvoja vastustava vaikutus, niiden valmistus ja terapeuttiset käytöt
NO975666L (no) Pyrrolderivater og medisinsk sammensetning
DE3773415D1 (de) Flavonkarbonsaeure-derivate.
DE3777852D1 (de) Dekahydrochinolinderivate, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
TR199902495T2 (xx) Bile�imler.
DE69215694T2 (de) Benzamid-derivate
ATE18196T1 (de) 1,4-acyloxynaphthalenderivate, diese enthaltende kompositionen, verfahren fuer ihre herstellung und zwischenprodukte dafuer.
NO177995C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 1,3-dioksanderivater
DE60027908D1 (de) Harnstoff-verbindungen, ein verfahren zu deren herstellung und ihre verwendung
NO161493C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1,6-nafthyridinderivater.
EP0322153A3 (de) Heterozyklyl Oxophtalazynyl-Essigsäuren
RO115873B1 (ro) Derivaţi de acid hidroximic, procedee de obţinere a acestora, intermediari pentru realizarea unuia dintre procedee şi compoziţie farmaceutică
DE69130266D1 (de) Optisch wirksame Alkylendioxybenzolderivate und ihre Verwendung als Arzneimittel
DE69428206T2 (de) Chinolincarbonsäurederivate und ihre salze
ES2193168T3 (es) Nuevos derivados de acido parabanico como inhibidores de aldosa reductasa.
WO2003018564A1 (fr) Inhibiteur d'acat selectif de la paroi vasculaire
AU547599B2 (en) Tricyclic compounds
FR2823749B1 (fr) Phenyl- et pyridyl-piperidines, procede pour leur preparation et compositions pharmaceutiques les contenant
EA200200462A1 (ru) Производные 2-арилхинолина, их получение и терапевтическое применение
KR950032159A (ko) 티아디아지논 유도체

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee