DE69221685D1 - Verfahren zur herstellung von optisch aktivem 3-chlor-1-phenyl-propan-1-ol und dessen derivat - Google Patents
Verfahren zur herstellung von optisch aktivem 3-chlor-1-phenyl-propan-1-ol und dessen derivatInfo
- Publication number
- DE69221685D1 DE69221685D1 DE69221685T DE69221685T DE69221685D1 DE 69221685 D1 DE69221685 D1 DE 69221685D1 DE 69221685 T DE69221685 T DE 69221685T DE 69221685 T DE69221685 T DE 69221685T DE 69221685 D1 DE69221685 D1 DE 69221685D1
- Authority
- DE
- Germany
- Prior art keywords
- propan
- chlorine
- phenyl
- derivative
- optically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
- C12N9/20—Triglyceride splitting, e.g. by means of lipase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/913—Aspergillus
- Y10S435/917—Aspergillus niger
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/921—Candida
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/933—Penicillium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/939—Rhizopus
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2452991 | 1991-02-19 | ||
PCT/JP1992/000159 WO1992014835A1 (en) | 1991-02-19 | 1992-02-18 | Process for producing optically active 3-chloro-1-phenyl-1-propanol and derivative thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69221685D1 true DE69221685D1 (de) | 1997-09-25 |
DE69221685T2 DE69221685T2 (de) | 1997-12-11 |
Family
ID=12140685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69221685T Expired - Fee Related DE69221685T2 (de) | 1991-02-19 | 1992-02-18 | Verfahren zur herstellung von optisch aktivem 3-chlor-1-phenyl-propan-1-ol und dessen derivat |
Country Status (4)
Country | Link |
---|---|
US (1) | US5457052A (de) |
EP (1) | EP0529085B1 (de) |
DE (1) | DE69221685T2 (de) |
WO (1) | WO1992014835A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3133480B2 (ja) * | 1992-04-15 | 2001-02-05 | 昭和シェル石油株式会社 | 光学活性ハロゲン含有アルコールの製造方法 |
DE4217506A1 (de) * | 1992-05-27 | 1993-12-02 | Boehringer Mannheim Gmbh | Mikrobielle Esterase zur enantioselektiven Spaltung von 1-Arylalkylestern |
FR2692909B1 (fr) * | 1992-06-24 | 1995-07-21 | Irceba | Procede de preparation d'aryl-1 alcanols substitues optiquement purs. |
US5841001A (en) * | 1996-02-28 | 1998-11-24 | Mitsubishi Chemical Corporation | Process for the preparation of optically active 2-halo-1-(substituted phenyl) ethanol |
US5959159A (en) * | 1997-10-24 | 1999-09-28 | Molecular Optoelectronics Corporation | Method for preparing optically active 5-hydroxy-3-(4'-hydroxyphenyl)-1,1,3-trimethylindane |
EP1407009A2 (de) * | 2000-12-01 | 2004-04-14 | Diversa Corporation | Hydrolasen enzyme und deren verwendungen auf kinetischer auflösung |
KR20080072105A (ko) * | 2004-08-26 | 2008-08-05 | 화이자 인코포레이티드 | 단백질 티로신 키나제 저해제 중간체의 제조를 위한거울상이성질선택적 생물학적 전환 |
CN105445384B (zh) * | 2014-08-26 | 2018-02-02 | 广州朗圣药业有限公司 | 3‑氯苯丙醇光学异构体的分离检测方法及其应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2707076B2 (ja) * | 1987-05-01 | 1998-01-28 | チッソ株式会社 | 光学活性化合物の製造法 |
DE3743824C2 (de) * | 1987-12-23 | 1997-03-06 | Hoechst Ag | Verfahren zur enzymatischen Racematspaltung von racemischen Alkoholen mit/in Vinylestern durch Umesterung |
US4868344A (en) * | 1988-03-30 | 1989-09-19 | Aldrich-Boranes, Inc. | Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein |
GB9005467D0 (en) * | 1990-03-12 | 1990-05-09 | Ici Plc | Process for the preparation of optically active intermediates for insecticidal compounds |
-
1992
- 1992-02-18 WO PCT/JP1992/000159 patent/WO1992014835A1/ja active IP Right Grant
- 1992-02-18 DE DE69221685T patent/DE69221685T2/de not_active Expired - Fee Related
- 1992-02-18 EP EP92905008A patent/EP0529085B1/de not_active Expired - Lifetime
-
1994
- 1994-04-25 US US08/232,589 patent/US5457052A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0529085A4 (en) | 1994-08-24 |
EP0529085B1 (de) | 1997-08-20 |
US5457052A (en) | 1995-10-10 |
EP0529085A1 (de) | 1993-03-03 |
DE69221685T2 (de) | 1997-12-11 |
WO1992014835A1 (en) | 1992-09-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |