DE69214180T2 - Verwendung von Bis-(p-Hydroxyphenylthio)methanderivaten zur Hemmung der fortschreitenden Entwicklung von insulinabhängingem Diabetes mellitus - Google Patents

Verwendung von Bis-(p-Hydroxyphenylthio)methanderivaten zur Hemmung der fortschreitenden Entwicklung von insulinabhängingem Diabetes mellitus

Info

Publication number
DE69214180T2
DE69214180T2 DE69214180T DE69214180T DE69214180T2 DE 69214180 T2 DE69214180 T2 DE 69214180T2 DE 69214180 T DE69214180 T DE 69214180T DE 69214180 T DE69214180 T DE 69214180T DE 69214180 T2 DE69214180 T2 DE 69214180T2
Authority
DE
Germany
Prior art keywords
insulin
diabetes mellitus
dependent diabetes
hydroxyphenylthio
inhibit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69214180T
Other languages
English (en)
Other versions
DE69214180D1 (de
Inventor
Keith M Robinson
Richard L Jackson
Eric W Heineke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE69214180D1 publication Critical patent/DE69214180D1/de
Application granted granted Critical
Publication of DE69214180T2 publication Critical patent/DE69214180T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/29Antimony or bismuth compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69214180T 1991-03-18 1992-03-17 Verwendung von Bis-(p-Hydroxyphenylthio)methanderivaten zur Hemmung der fortschreitenden Entwicklung von insulinabhängingem Diabetes mellitus Expired - Fee Related DE69214180T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67066891A 1991-03-18 1991-03-18
US72768791A 1991-07-10 1991-07-10

Publications (2)

Publication Number Publication Date
DE69214180D1 DE69214180D1 (de) 1996-11-07
DE69214180T2 true DE69214180T2 (de) 1997-02-06

Family

ID=27100370

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69214180T Expired - Fee Related DE69214180T2 (de) 1991-03-18 1992-03-17 Verwendung von Bis-(p-Hydroxyphenylthio)methanderivaten zur Hemmung der fortschreitenden Entwicklung von insulinabhängingem Diabetes mellitus

Country Status (8)

Country Link
EP (1) EP0504807B1 (de)
JP (1) JPH05229935A (de)
KR (1) KR920017661A (de)
AT (1) ATE143591T1 (de)
AU (1) AU651873B2 (de)
DE (1) DE69214180T2 (de)
DK (1) DK0504807T3 (de)
IE (1) IE920842A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6934558B1 (en) 1993-12-15 2005-08-23 Mlr, Llc Adaptive omni-modal radio apparatus and methods
US6961584B2 (en) 2000-03-22 2005-11-01 Mlr, Llc Tiered wireless, multi-modal access system and method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869202D1 (de) * 1987-03-17 1992-04-23 Merrell Dow Pharma Alkylidendithiobis (substituierte) phenolen zur hemmung der freisetzung von interleukin-1 und zur linderung von interleukin-1 vermittelten krankheiten.
US4900757A (en) * 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
US4959392A (en) * 1989-07-24 1990-09-25 Merrell Dow Pharmaceuticals Inc. Method of treating diabetes mellitus

Also Published As

Publication number Publication date
IE920842A1 (en) 1992-09-23
JPH05229935A (ja) 1993-09-07
EP0504807B1 (de) 1996-10-02
DE69214180D1 (de) 1996-11-07
AU651873B2 (en) 1994-08-04
AU1287892A (en) 1992-09-24
ATE143591T1 (de) 1996-10-15
EP0504807A1 (de) 1992-09-23
DK0504807T3 (da) 1996-11-18
KR920017661A (ko) 1992-10-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee