DE69213049D1 - Isoquinolinderivate - Google Patents
IsoquinolinderivateInfo
- Publication number
- DE69213049D1 DE69213049D1 DE69213049T DE69213049T DE69213049D1 DE 69213049 D1 DE69213049 D1 DE 69213049D1 DE 69213049 T DE69213049 T DE 69213049T DE 69213049 T DE69213049 T DE 69213049T DE 69213049 D1 DE69213049 D1 DE 69213049D1
- Authority
- DE
- Germany
- Prior art keywords
- isoquinoline derivatives
- activity
- arrhythmia
- chem
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
- C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5591591 | 1991-02-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69213049D1 true DE69213049D1 (de) | 1996-10-02 |
DE69213049T2 DE69213049T2 (de) | 1997-04-03 |
Family
ID=13012408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69213049T Expired - Fee Related DE69213049T2 (de) | 1991-02-27 | 1992-02-21 | Isoquinolinderivate |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0501693B1 (de) |
KR (1) | KR920016425A (de) |
AT (1) | ATE141918T1 (de) |
CA (1) | CA2061260A1 (de) |
DE (1) | DE69213049T2 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ527276A (en) | 2001-03-27 | 2004-11-26 | Actelion Pharmaceuticals Ltd | 1,2,3,4-tetrahydroisoquinoline derivatives as urotensin II receptor antagonists |
US6908931B2 (en) | 2003-04-10 | 2005-06-21 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline derivatives as melatonin MT2 antagonists |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4613606A (en) * | 1985-12-02 | 1986-09-23 | Syntex (U.S.A.) Inc. | Tetrahydroisoquinoline derivatives |
WO1990002119A1 (en) * | 1988-08-18 | 1990-03-08 | Banyu Pharmaceutical Co., Ltd. | 1,2,3,4-tetrahydroisoquinoline derivatives |
-
1992
- 1992-02-14 CA CA002061260A patent/CA2061260A1/en not_active Abandoned
- 1992-02-21 AT AT92301467T patent/ATE141918T1/de not_active IP Right Cessation
- 1992-02-21 DE DE69213049T patent/DE69213049T2/de not_active Expired - Fee Related
- 1992-02-21 EP EP92301467A patent/EP0501693B1/de not_active Expired - Lifetime
- 1992-02-27 KR KR1019920003019A patent/KR920016425A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ATE141918T1 (de) | 1996-09-15 |
KR920016425A (ko) | 1992-09-24 |
EP0501693A1 (de) | 1992-09-02 |
AU1121892A (en) | 1992-09-03 |
DE69213049T2 (de) | 1997-04-03 |
CA2061260A1 (en) | 1992-08-28 |
AU644513B2 (en) | 1993-12-09 |
EP0501693B1 (de) | 1996-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |